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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 7,776–7,800 of 27,380 studies, newest first · page 312 of 1096.

April 2023 25

  1. 2023-04-12

    Serious Games for Learning Among Older Adults With Cognitive Impairment: Systematic Review and Meta-analysis

    ✓ Peer-reviewed Treatments Journal of medical Internet research

    Key finding: The results of the included studies were summarized using a narrative synthesis or meta-analysis, as appropriate. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2023-04-11

    Symptomatology in 4-repeat tauopathies is associated with data-driven topology of [18F]-PI-2620 tau-PET signal

    ✓ Peer-reviewed Brain scans and imaging NeuroImage. Clinical

    Key finding: As cerebral regions correlating with symptomatology differ depending on the clinical phenotype, a precise knowledge of clinical signs and symptoms is necessary when interpreting [18F]PI-2620 PET results.

    Full summary, score breakdown and related studies → Original source

  3. 2023-04-11

    Amyloid-beta aggregation implicates multiple pathways in Alzheimer's disease: Understanding the mechanisms

    ✓ Peer-reviewed Drug development Frontiers in neuroscience

    Key finding: It has been associated with neuronal damage, synaptic dysfunction, and cognitive deficits.

    Full summary, score breakdown and related studies → Original source

  4. 2023-04-11

    Utilization and performance of long-term care system for older people with disabilities and dementia in Zhejiang Province, China

    ✓ Peer-reviewed Health systems and care delivery Frontiers in psychiatry

    Key finding: Significant improvements were observed in most LTC performance indicators for OPWDD, such as input, process, and outcome, with notable enhancements in fairness, accessibility, and affordability of LTC services. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2023-04-10

    Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4

    ✓ Peer-reviewed Genetics Neuron

    Key finding: Aberrant low γ-secretase activity is associated with most of the presenilin mutations that underlie familial Alzheimer's disease (fAD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2023-04-10

    A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures

    ✓ Peer-reviewed TREM2 and immune genetics Nature metabolism

    Key finding: It is unclear how progression of NAFLD towards cirrhosis translates into systematic changes in circulating proteins. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2023-04-09

    The TREM2 H157Y Variant Influences Microglial Phagocytosis, Polarization, and Inflammatory Cytokine Release

    ✓ Peer-reviewed TREM2 and immune genetics Brain sciences

    Key finding: Previously, we reported that H157Y, a rare coding variant on exon 3 of the triggering receptor expressed on myeloid cells 2 gene (TREM2), was associated with Alzheimer's disease (AD) risk in a Han Chinese population. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2023-04-09

    Plasma p-tau181 and p-tau217 in discriminating PART, AD and other key neuropathologies in older adults

    ✓ Peer-reviewed Biomarkers Acta neuropathologica

    Key finding: Both p-tau markers were associated with greater odds of AD, but p-tau217 had higher accuracy (area under the ROC curve (AUC): 0.83) than p-tau181 (AUC: 0.76). +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2023-04-07

    Sleep and circadian rhythms in α-synucleinopathies-Perspectives for disease modification

    ✓ Peer-reviewed Risk factors Acta physiologica (Oxford, England)

    Key finding: Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) has been identified as a prodromal state of α-synucleinopathies, such as Parkinson's disease, Lewy body dementia, and multiple system atrophy offering a window for insights into the early development of these diseases. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2023-04-07

    Prognostic value of cerebrospinal fluid biomarkers in mild cognitive impairment due to Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers Neurologia

    Key finding: We selected patients diagnosed with mild cognitive impairment due to AD (National Institute on Aging-Alzheimer's Association clinical criteria), confirmed neuropsychological deficit, a Global Deterioration Scale score of 3, and an abnormal profile of cerebrospinal fluid biomarkers. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2023-04-07

    Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation

    ✓ Peer-reviewed TREM2 and immune genetics Science immunology

    Key finding: Identifying key macrophage populations found in human fibrotic tissues could lead to new treatments for fibrosis. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2023-04-06

    Cost effectiveness of non-drug interventions that reduce nursing home admissions for people living with dementia

    ✓ Peer-reviewed Costs and economics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: All four interventions cost less and are more effective (i.e., cost savings) than usual care from a societal perspective. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2023-04-06

    Retinal imaging in animal models: Searching for biomarkers of neurodegeneration

    ✓ Peer-reviewed Brain scans and imaging Frontiers in ophthalmology

    Key finding: We report on thickness variations of the retina and retinal layers/layer aggregates caused by healthy aging and AD-like conditions and discuss the implications of focusing research efforts solely on retinal thickness. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2023-04-06

    Vascular Risk Predicts Plasma Amyloid β 42/40 Through Cerebral Amyloid Burden in Apolipoprotein E ε4 Carriers

    ✓ Peer-reviewed Biomarkers Stroke

    Key finding: Vascular risk significantly predicted cerebral amyloid burden in Alzheimer's Disease Neuroimaging Initiative but not in the UCD-ADRC cohort. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2023-04-06

    Identifying modifiable factors and their joint effect on dementia risk in the UK Biobank

    ✓ Peer-reviewed Long-term cohort studies Nature human behaviour

    Key finding: However, the multiplicity and co-occurrence of risk factors have been underestimated. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2023-04-06

    A global view of the genetic basis of Alzheimer disease

    ✓ Peer-reviewed Genetics Nature reviews. Neurology

    Key finding: Rare, autosomal dominant forms of AD occur in middle age as a result of highly penetrant genetic mutations, but the most common form of AD occurs later in life. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2023-04-05

    Ambient air pollution and clinical dementia: systematic review and meta-analysis

    ✓ Peer-reviewed Prevention and risk BMJ

    Key finding: PM 2.5 might be a risk factor for dementia, as well as nitrogen dioxide and nitrogen oxide, although with more limited data. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2023-04-05

    The Relationship of Omega-3 Fatty Acids with Dementia and Cognitive Decline: Evidence from Prospective Cohort Studies of Supplementation, Dietary Intake, and Blood Markers

    ✓ Peer-reviewed Prevention and risk American Journal of Clinical Nutrition

    Key finding: After incorporating 48 longitudinal studies involving 103,651 participants, a moderate-to-high level of evidence suggested that dietary intake of omega-3 fatty acids could lower risk of all-cause dementia or cognitive decline by ∼20%, especially for docosahexaenoic acid (DHA) intake (relative risk [RR]: 0.82, I 2 = 63.6%, P = 0.001) and for studies that were adjusted for apolipoprotein APOE ε4 status (RR: 0.83, I 2 = 65%, P = 0.006). +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2023-04-04

    Multi-omic integration via similarity network fusion to detect molecular subtypes of ageing

    ✓ Peer-reviewed Genetics Brain communications

    Key finding: Fusion of all five data modalities (n = 111) yielded two subtypes (n S1 = 53, n S2 = 58), which were nominally associated with diffuse amyloid plaques; however, this effect was not significant after correction for multiple testing. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2023-04-04

    Role of Hydroxytyrosol and Oleuropein in the Prevention of Aging and Related Disorders: Focus on Neurodegeneration, Skeletal Muscle Dysfunction and Gut Microbiota

    ✓ Peer-reviewed Prevention trials Nutrients

    Key finding: Aging is a multi-faceted process caused by the accumulation of cellular damage over time, associated with a gradual reduction of physiological activities in cells and organs. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2023-04-04

    A Pilot to Implement Chronic Care Management Services at an Academic Medical Center

    ✓ Peer-reviewed Health systems and care delivery Gerontology & geriatric medicine

    Key finding: One thousand sixty-six dollars ($1,066) were collected for CCM. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2023-04-03

    Hospice Quality, Race, and Disenrollment in Hospice Enrollees With Dementia

    ✓ Peer-reviewed Disparities Journal of palliative medicine

    Key finding: The sample included 673,102 PWD (mean age 86, 66% female, 85% White, 7.3% Black, 6.3% Hispanic, 1.6% AAPI) enrolled in 4371 hospices nationwide. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2023-04-03

    Plasma phosphorylated tau 181 predicts amyloid status and conversion to dementia stage dependent on renal function

    ✓ Peer-reviewed Biomarkers Journal of neurology, neurosurgery, and psychiatry

    Key finding: Plasma P-tau181 effectively detects Aβ+ status and conversion to dementia, confirming the value of this blood biomarker for the management of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2023-04-03

    A randomized, open-label clinical trial in mild cognitive impairment with EGb 761 examining blood markers of inflammation and oxidative stress

    ✓ Peer-reviewed Inflammation and the immune system Scientific reports

    Key finding: The Olink Proteomics panel of inflammation markers ( https://www.olink.com/products/inflammation/ ) will be used to evaluate 92 proteins associated with inflammatory diseases and related biological processes. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2023-04-03

    Lecanemab for Patients With Early Alzheimer Disease: Bayesian Analysis of a Phase 2b Dose-Finding Randomized Clinical Trial

    ✓ Peer-reviewed Treatments JAMA network open

    Key finding: Innovations associated with the bayesian approach can improve the efficiency of drug development and the accuracy of clinical trials, even in the context of substantial data missingness. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →