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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 8,401–8,425 of 27,380 studies, newest first · page 337 of 1096.

October 2022 25

  1. 2022-10-09

    Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4

    ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The Alzheimer's Disease Neuroimaging Initiative (ADNI) aims to validate biomarkers for Alzheimer's disease (AD) clinical trials.

    Full summary, score breakdown and related studies → Original source

  2. 2022-10-08

    Aluminum neurotoxicity and autophagy: a mechanistic view

    ✓ Peer-reviewed Disease mechanisms Neurological research

    Key finding: It is strongly believed that aluminum is one of the insalubrious agents because of its neurotoxicity effects and influences on amyloid β (Aβ) production and tau protein hyperphosphorylation following oxidative stress, as one of the initial events in neurotoxicity. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2022-10-08

    Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease

    ✓ Peer-reviewed Genetics Communications biology

    Key finding: Genome-wide and transcriptome-wide association studies have identified various genes and genetic variants in lipid metabolism that are associated with Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  4. 2022-10-07

    Growth of Fee-for-Service Medicare Home-Based Medical Care Within Private Residences and Domiciliary Care Settings in the U.S., 2012-2019

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Medical Directors Association

    Key finding: The median (interquartile range) state-level HBMC utilization rate per 1000 FFS population was 67.6 (34.1-151.3) visits overall, 17.3 (7.9-41.9) visits in private residences, and 47.7 (23.1-86.6) visits in domiciliary settings. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2022-10-06

    Serum lipid traits and the risk of dementia: A cohort study of 254,575 women and 214,891 men in the UK Biobank

    ✓ Peer-reviewed Long-term cohort studies EClinicalMedicine

    Key finding: Serum lipid traits are associated with cardiovascular disease, but uncertainty remains regarding their associations with dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2022-10-05

    Diabetes and dementia: Clinical perspective, innovation, knowledge gaps

    ✓ Peer-reviewed Risk factors Journal of diabetes and its complications

    Key finding: It concluded, along with other studies, that diabetes as well as obesity and the metabolic syndrome more broadly, which are frequently comorbid, raise the risk of developing dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2022-10-05

    Biomarkers of neurodegeneration in neural autoantibody-associated psychiatric syndromes: A retrospective cohort study

    ✓ Peer-reviewed Tau biomarkers Journal of translational autoimmunity

    Key finding: Autoantibody-associated psychiatric syndromes are a novel disease entity that is not fully understood. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2022-10-03

    Limbic-Predominant Age-Related TDP-43 Encephalopathy: LATE-Breaking Updates in Clinicopathologic Features and Biomarkers

    ✓ Peer-reviewed Brain tissue and pathology Current neurology and neuroscience reports

    Key finding: Limbic-predominant age-related TDP-43 encephalopathy (LATE) is a recently defined neurodegenerative disease characterized by amnestic phenotype and pathological inclusions of TAR DNA-binding protein 43 (TDP-43). +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2022-10-03

    Interaction between autophagy and the NLRP3 inflammasome in Alzheimer's and Parkinson's disease

    ✓ Peer-reviewed Inflammation and the immune system Frontiers in aging neuroscience

    Key finding: However, the related mechanism is not entirely clear. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2022-10-03

    Long-term particulate matter 2.5 exposure and dementia: a systematic review and meta-analysis

    ✓ Peer-reviewed Risk factors Public health

    Key finding: In total, 20 articles were selected for review; 18 included results on the long-term effects of PM2.5 on dementia, 13 on AD, and eight on VaD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2022-10-03

    Therapeutic drug repositioning with special emphasis on neurodegenerative diseases: Threats and issues

    ✓ Peer-reviewed Drug development Frontiers in pharmacology

    Key finding: Kinase inhibitors, for example, which were developed for various oncology indications, demonstrated significant neuroprotective effects in neurodegenerative diseases.

    Full summary, score breakdown and related studies → Original source

  12. 2022-10-03

    Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive Individuals

    ✓ Peer-reviewed Tau biomarkers Neurology

    Key finding: In this retrospective study, GAP-43 was measured in participants from the AD Neuroimaging Initiative (ADNI) cohort using an in-house ELISA method, and levels were compared between groups, both cross-sectionally and longitudinally. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2022-10-03

    Effect of Exercise Training or Complex Mental and Social Activities on Cognitive Function in Adults With Chronic Stroke: A Randomized Clinical Trial

    ✓ Peer-reviewed Treatments JAMA network open

    Key finding: One-hundred and twenty participants, with a mean (range) of 1.2 (1-4) strokes, a mean (SD) of 66.5 (53.8) months since the most recent stroke, mean (SD) baseline age of 70 (8) years, mean (SD) baseline ADAS-Cog-Plus of 0.22 (0.81), and 74 (62%) male participants, were randomized to EX (34 participants), ENRICH (34 participants), or BAT (52 participants). +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2022-10-03

    Association of Plasma and Cerebrospinal Fluid Alzheimer Disease Biomarkers With Race and the Role of Genetic Ancestry, Vascular Comorbidities, and Neighborhood Factors

    ✓ Peer-reviewed Biomarkers JAMA network open

    Key finding: In this cross-sectional study of plasma biomarkers by race and genetic ancestry, the results indicated that plasma p-tau181, Aβ40, and NFL were lower in African American individuals based on self-reported race but not genetic ancestry. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2022-10-03

    Racial and Ethnic Differences in Amyloid PET Positivity in Individuals With Mild Cognitive Impairment or Dementia: A Secondary Analysis of the Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Cohort Study

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: Data from 17 107 individuals (321 Asian, 635 Black, 829 Hispanic, and 15 322 White) with MCI or dementia and amyloid PET were analyzed between April 2020 and January 2022. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2022-10-02

    Comparison of plasma and CSF biomarkers in predicting cognitive decline

    ✓ Peer-reviewed Biomarkers Annals of clinical and translational neurology

    Key finding: Both plasma and CSF measures of Aβ42/Aβ40 and NfL predicted cognitive decline. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2022-10 month only

    Association between depression, gender and Alzheimer's neuropathology in older adults without dementia

    ✓ Peer-reviewed Risk factors International journal of geriatric psychiatry

    Key finding: This study included 407 participants (96 Thal, 405 Braak, and 406 CERAD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2022-10 month only

    Blood based biomarkers for movement disorders

    ✓ Peer-reviewed Biomarkers Acta neurologica Scandinavica

    Key finding: NfL is also a prognostic biomarker, in that the level of baseline or cross-sectional plasma/serum NfL is associated with a worse prognosis in PD and PSP.

    Full summary, score breakdown and related studies → Original source

  19. 2022-10-01

    Effects of postoperative cognitive training on neurocognitive decline after heart surgery: a randomized clinical trial

    ✓ Peer-reviewed Prevention trials European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    Key finding: Since our cognitive training showed beneficial effects, it could be a promising method to prevent POCD.

    Full summary, score breakdown and related studies → Original source

  20. 2022-10-01

    The Blondes of Wisconsin

    ✓ Peer-reviewed Risk factors Polish American Studies

    Key finding: Still, there's something earnest and noble in his face” (p. 126). +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2022-10-01

    CSF Alzheimer Disease Biomarkers: Time-Varying Relationships With MCI Symptom Onset and Associations With Age, Sex, and ApoE4

    ✓ Peer-reviewed Tau biomarkers Neurology

    Key finding: This study aimed to examine whether baseline CSF measures of Alzheimer disease (AD)-related pathology are associated with the time to onset of mild cognitive impairment (MCI) and whether these associations differ by age, sex, Apolipoprotein E ( ApoE4 ) status, and proximal (≤7 years) vs distal (>7 years) time to symptom onset. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2022-10-01

    TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways

    ✓ Peer-reviewed TREM2 and immune genetics Cell

    Key finding: Microglia that adhere to Aβ plaques acquire a transcriptional signature, "disease-associated microglia" (DAM), which largely emanates from the TREM2-DAP12 receptor complex that transmits intracellular signals through the protein tyrosine kinase SYK. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2022-10-01

    Association of Elevated Amyloid and Tau Positron Emission Tomography Signal With Near-Term Development of Alzheimer Disease Symptoms in Older Adults Without Cognitive Impairment

    ✓ Peer-reviewed Brain scans and imaging JAMA neurology

    Key finding: Among 580 participants (PREVENT-AD, 128; HABS, 153; AIBL, 48; Knight ADRC, 251), mean (SD) age ranged from 67 (5) to 76 (6) years across cohorts, with between 55% (137/251) and 74% (95/128) female participants. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2022-10-01

    Association of Amyloid Reduction After Donanemab Treatment With Tau Pathology and Clinical Outcomes: The TRAILBLAZER-ALZ Randomized Clinical Trial

    ✓ Peer-reviewed Treatments JAMA neurology

    Key finding: The primary study randomized 272 participants (mean [SD] age, 75.2 [5.5] years; 145 female participants [53.3%]). +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2022-10-01

    Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology

    ✓ Peer-reviewed Biomarkers Brain : a journal of neurology

    Key finding: The extent to which the pathophysiology of autosomal dominant Alzheimer's disease corresponds to the pathophysiology of 'sporadic' late onset Alzheimer's disease is unknown, thus limiting the extrapolation of study findings and clinical trial results in autosomal dominant Alzheimer's disease to late onset Alzheimer's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →