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Home › Research › Clinical trials

Clinical trials

Every Alzheimer's trial in our copy of the ClinicalTrials.gov registry — completed, running and abandoned. Filter it, then follow the link to the official record.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

Clear filters Download all 7,816 as CSV

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 1–25 of 7,816 matching trials · page 1 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's
NCT03649724
Placebo; Eligard 22.5Mg Suspension for Injection
Runs in: United States · 3 sites 		PHASE2
symptomatic-cholinergic		 COMPLETED 86 Weill Medical College of Cornell University
OTHER		 2026-09-21
The Revitalize Study in Older Adults at Risk for Alzheimer's Disease
NCT04018092
Active NIR-PBM; Sham NIR-PBM
Runs in: United States · 2 sites 		PHASE2
other		 COMPLETED 168 University of Florida
OTHER		 2026-09-21
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
NCT04031469
There is no intervention in this study
Runs in: United States · 1 site 		NA
other		 SUSPENDED 1,000 ProgenaBiome
OTHER		 2026-09-21
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)
NCT04374136
Part 1 Blinded - AL001; Part 1 Blinded - Placebo; Part 2 (OLE Treat...
Runs in: Argentina; Australia; Belgium; Canada; France; Germany; G... · 44 sites 		PHASE3
other		 TERMINATED 119 Alector Inc.
INDUSTRY		 2026-09-21
Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons
NCT05048966
Group Wellness Class 1; Group Wellness Class 2
Runs in: United States · 1 site 		NA
other		 RECRUITING 360 Kessler Foundation
OTHER		 2026-09-21
SYNERGIC-2 Trial (SYNchronizing, Exercises and Remedies to GaIn Cognition@Home)
NCT05375513
PMI@Home; Brain Health Pro
Runs in: Canada · 8 sites 		NA
other		 RECRUITING 250 London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
OTHER		 2026-09-21
PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620
NCT05456503
[18F]-PI-2620
Runs in: United States · 1 site 		PHASE3
other		 RECRUITING 72 University of Pennsylvania
OTHER		 2026-09-21
Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers
NCT05596760
Jumpstart Guide
Runs in: United States · 3 sites 		NA
other		 ACTIVE_NOT_RECRUITING 1,802 University of Washington
OTHER		 2026-09-21
Effect of Acetylcholinesterase Inhibitors on Bone Metabolism
NCT06041789
Donepezil; Memantine
Runs in: United States · 1 site 		PHASE2
symptomatic-cholinergic		 RECRUITING 45 Duke University
OTHER		 2026-09-21
Promoting Physical Activity in Older Hispanic/Latino(a) Adults
NCT06362824
De Pie Intervention; Active Comparison Group: Healthy Actions And L...
Runs in: United States · 2 sites 		NA
other		 ACTIVE_NOT_RECRUITING 130 Kaiser Permanente
OTHER		 2026-09-21
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
NCT06847321
LHP588; LHP588; Placebo Drug
Runs in: United States · 39 sites 		PHASE2
other		 RECRUITING 300 Lighthouse Pharmaceuticals, Inc.
INDUSTRY		 2026-09-21
Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging
NCT07099053
Runs in: United States · 1 site 		NA
other		 RECRUITING 400 National Institute on Aging (NIA)
NIH		 2026-09-21
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
NCT07169630
18F-PF974; 18F-florbetaben
Runs in: United States · 1 site 		PHASE1
other		 RECRUITING 90 National Institute of Mental Health (NIMH)
NIH		 2026-09-21
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
NCT07177352
No Intervention
Runs in: Argentina; Australia; Brazil; Canada; Chile; China; Denma... · 229 sites 		PHASE3
other		 RECRUITING 80,000 Hoffmann-La Roche
INDUSTRY		 2026-09-21
Improving Neurological Health With Acetylcholine Via Neuroplasticity-based Computerized Exercise in Mild Cognitive Impairment
NCT07243600
Computerized speed-based cognitive training; Computerized executive...
Runs in: Canada · 1 site 		NA
other		 RECRUITING 84 Posit Science Corporation
INDUSTRY		 2026-09-21
Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease
NCT07378644
SKY-0515; SKY-0515 Placebo
Runs in: Argentina; Brazil; Canada; Chile; Colombia; Georgia; Germ... · 24 sites 		PHASE2|PHASE3
other		 RECRUITING 400 Skyhawk Therapeutics, Inc.
INDUSTRY		 2026-09-21
The Gut - PRO Study
NCT07413744
Probiotic; Placebo
Runs in: United States · 1 site 		PHASE1
other		 RECRUITING 40 University of Wisconsin, Madison
OTHER		 2026-09-21
Escalating Doses of Memantine in Down Syndrome (MEDS-123)
NCT07531940
Memantine
Runs in: United States · 1 site 		PHASE1
symptomatic-cholinergic		 NOT_YET_RECRUITING 25 University Hospitals Cleveland Medical Center
OTHER		 2026-09-21
Adapting Behavioral Interventions for Dementia to Address NCDs and Mental Health
NCT07543341
BECOME-D Intervention
Runs in: Nepal · 1 site 		NA
other		 COMPLETED 12 Possible
OTHER		 2026-09-21
Music for Pain and Dementia
NCT07602283
Drumming session; Music-listening session
Runs in: United States · 1 site 		NA
other		 RECRUITING 60 Yale University
OTHER		 2026-09-21
Comparing Two Acute Care Transition Programs for Older Adults and Their Family Caregivers
NCT07661355
Patient-Centered Program; Family Caregiver Enhanced Program
Runs in: United States · 4 sites 		NA
other		 RECRUITING 2,560 Wake Forest University Health Sciences
OTHER		 2026-09-21
A Retrospective Database Study for the Development and Validation of Algorithms for Intracerebral Hemorrhage and Seizures in Alzheimer's Disease
NCT07723950
No intervention
Runs in: United States · 1 site 		NA
other		 ACTIVE_NOT_RECRUITING 600 Eisai Inc.
INDUSTRY		 2026-09-21
Study to Test Effects and Safety of RO7568282 in Early Symptomatic Alzheimer's Disease
NCT07781657
RO7568282; Placebo 		PHASE2
other		 NOT_YET_RECRUITING 450 Hoffmann-La Roche
INDUSTRY		 2026-09-21
Microbiome in Aging of Gut and Brain
NCT07799402
Runs in: United States · 1 site 		NA
other		 RECRUITING 700 University of South Florida
OTHER		 2026-09-21
Virtual Reality Training to Support Daily Activities for People Living With Dementia
NCT07829913
At-Home VR-Based IADL Training; Cognitive Stimulation Activities 		NA
other		 NOT_YET_RECRUITING 40 Indiana University
OTHER		 2026-09-21

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →