Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 7,151–7,175 of 27,380 studies, newest first · page 287 of 1096.
November 2023 25
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2023-11-27
Alzheimer's disease and inflammatory biomarkers positively correlate in plasma in the UK-ADRC cohort
57/100 ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: Unique AD-inflammatory biomarker correlations in a community-based cohort reveal a new avenue for utilizing plasma-based biomarkers in the assessment of AD and related dementias. +1 more finding
Full summary, score breakdown and related studies → Original source
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2023-11-27
Association Between Triglycerides and Risk of Dementia in Community-Dwelling Older Adults: A Prospective Cohort Study
77/100 ✓ Peer-reviewed Treatments Neurology
Key finding: Older adults with higher triglyceride levels within the normal to high-normal range had a lower dementia risk and slower cognitive decline over time compared with individuals with lower triglyceride levels. +4 more findings
Full summary, score breakdown and related studies → Original source
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2023-11-25
The role of nutrition in the prevention of cognitive decline
43/100 ✓ Peer-reviewed Prevention and risk Current opinion in clinical nutrition and metabolic care
Key finding: Dementia is a growing concern and underscores the urgent need for effective preventive measures targeting modifiable risk factors.
Full summary, score breakdown and related studies → Original source
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2023-11-24
Ambroxol as a disease-modifying treatment to reduce the risk of cognitive impairment in GBA-associated Parkinson's disease: a multicentre, randomised, double-blind, placebo-controlled, phase II trial. The AMBITIOUS study protocol
45/100 ✓ Peer-reviewed Clinical trials BMJ neurology open
Key finding: GBA-related PD (GBA-PD) patients have higher risk of dementia and reduced survival than non-carriers. +2 more findings
Full summary, score breakdown and related studies → Original source
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2023-11-24
Social and Behavior Factors of Alzheimer's Disease and Related Dementias: A National Study in the U.S
39/100 ✓ Peer-reviewed Risk factors American journal of preventive medicine
Key finding: Lifestyle factors ranked highly in non-disadvantaged counties compared to more environmental factors in disadvantaged counties.
Full summary, score breakdown and related studies → Original source
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2023-11-23
A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment
79/100 ✓ Peer-reviewed Genetics GeroScience
Key finding: Walking speed in the placebo group significantly improved across the study duration suggestive of a practice effect but did not change in the NR group (p = 0.0402 and p = 0.4698, respectively). +1 more finding
Full summary, score breakdown and related studies → Original source
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2023-11-23
How to engage patients in computerized cognitive training: a cognitive rehabilitation expert's perspective
43/100 ✓ Peer-reviewed Cognitive tests and assessment Disability and rehabilitation. Assistive technology
Key finding: Two major themes were identified: (1) facilitating factors and (2) difficulties related to use. +4 more findings
Full summary, score breakdown and related studies → Original source
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2023-11-23
Efficacy of smartphone application-based multi-domain cognitive training in older adults without dementia
52/100 ✓ Peer-reviewed Cognitive tests and assessment Frontiers in aging neuroscience
Key finding: Of 101 participants, 85 older adults without dementia (84.1%) who completed the study protocol were included in the statistical analysis. +4 more findings
Full summary, score breakdown and related studies → Original source
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2023-11-23
Serum biomarkers associated with aging and neurodegeneration in common marmosets (Callithrix jacchus)
50/100 ✓ Peer-reviewed Biomarkers Neuroscience letters
Key finding: Aged marmosets (>7 years) had significantly higher GFAP, NfL, UCH-L1, and T-tau than adult marmosets.
Full summary, score breakdown and related studies → Original source
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2023-11-23
Imaging of Amyloid-Related Imaging Abnormalities (ARIA)
41/100 ✓ Peer-reviewed Treatments RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
Key finding: In asymptomatic patients, discontinuation of the drug might be sufficient. +4 more findings
Full summary, score breakdown and related studies → Original source
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2023-11-22
[Alzheimer's disease. Current evidence on the preventive role of nutrition]
41/100 ✓ Peer-reviewed Prevention and risk Nutricion hospitalaria
Key finding: several dietary components have been positively associated with AD prevention, including intake of complex carbohydrates, fiber, omega-3, plant-based proteins, vitamins (folates, choline, vitamin D, C, B6 and B9), zinc, some bioactive compounds such as flavonols and probiotics. +1 more finding
Full summary, score breakdown and related studies → Original source
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2023-11-22
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist
43/100 ✓ Peer-reviewed Genetics Neuron
Key finding: In the P301S mouse model of tauopathy, ApoE4 increases tau pathology and neurodegeneration when compared with ApoE3 or the absence of ApoE. +1 more finding
Full summary, score breakdown and related studies → Original source
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2023-11-21
Five lessons from Alzheimer disease
24/100 ✓ Peer-reviewed Risk factors JAAPA
Key finding: First, family members bear witness to the behavioral debility, memory decline, and loss of expression associated with Alzheimer disease.
Full summary, score breakdown and related studies → Original source
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2023-11-20
A limbic-predominant amnestic neurodegenerative syndrome associated with TDP-43 pathology
16/100 ⚠ Preprint — not yet peer-reviewed Brain tissue and pathology medRxiv : the preprint server for health sciences
Key finding: When seen in isolation, LATE-NC have been associated with a predominantly amnestic profile and slow clinical progression. +3 more findings
Scored 35 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2023-11-20
Biological variation estimates of Alzheimer's disease plasma biomarkers in healthy individuals
55/100 ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: BV estimates for AD plasma biomarkers can potentially refine their clinical and research interpretation. +4 more findings
Full summary, score breakdown and related studies → Original source
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2023-11-20
Consensus definition of advance care planning in dementia: A 33-country Delphi study
48/100 ✓ Peer-reviewed End-of-life care Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: A communication and relationship-centered definitional framework of ACP in dementia evolved through international consensus supporting inclusiveness of persons with dementia and their family.
Full summary, score breakdown and related studies → Original source
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2023-11-20
Greater socioenvironmental risk factors and higher chronic pain stage are associated with thinner bilateral temporal lobes
42/100 ✓ Peer-reviewed Risk factors Brain and Behavior
Key finding: Regression analyses showed that with the inclusion of socioenvironmental factors, the model was significant (p < .001), and sociodemographic (ethnic/race) group differences were not significant (p = .118). +3 more findings
Full summary, score breakdown and related studies → Original source
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2023-11-19
Food Insecurity, Race and Ethnicity, and Cognitive Function Among United States Older Adults
59/100 ✓ Peer-reviewed Disparities The Journal of nutrition
Key finding: Compared with food secure older adults, those reporting food insecurity experienced worsened cognitive functioning over time (B = -0.63, p < .001), and they were more likely to have onset of cognitive impairment (OR= 1.46, p < .001) in the 6-y observation. +4 more findings
Full summary, score breakdown and related studies → Original source
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2023-11-18
Neurochemical Ameliorating of the Hippocampus in Dyslipidemic Alzheimer Patients Following Silymarin; a Double-Blind Placebo-Controlled Randomized Clinical Trial
39/100 ✓ Peer-reviewed Treatments Medical journal of the Islamic Republic of Iran
Key finding: Donepezil and silymarin improved lipid profile associated with increased NAA/Cr, and decreased mI/Cr, in AD patients. +3 more findings
Full summary, score breakdown and related studies → Original source
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2023-11-17
Efficacy of anti-amyloid-ß monoclonal antibody therapy in early Alzheimer's disease: a systematic review and meta-analysis
86/100 ✓ Peer-reviewed Treatments Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Key finding: Anti-amyloid-ß mAbs attenuate cognitive and functional decline compared with placebo in early AD; whether the magnitude of this effect is clinically important remains uncertain, especially relative to the safety profile of these medications. +4 more findings
Full summary, score breakdown and related studies → Original source
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2023-11-17
A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's disease
62/100 ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: UGOT p-tau217 can be an easily accessible and efficient way to screen and monitor patients with suspected AD pathophysiology, even in the early stages of the continuum.
Full summary, score breakdown and related studies → Original source
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2023-11-16
Predicting amyloid PET positivity using plasma p-tau181 and other blood-based biomarkers
66/100 ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia (Amsterdam, Netherlands)
Key finding: In the Asan cohort, after adjusting for age and sex, p-tau181 (AUC = 0.854) or APOE ε4 status (AUC = 0.769) distinguished Aβ status with high accuracy. +4 more findings
Full summary, score breakdown and related studies → Original source
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2023-11-16
A review of the flortaucipir literature for positron emission tomography imaging of tau neurofibrillary tangles
46/100 ✓ Peer-reviewed Brain scans and imaging Brain communications
Key finding: We found 474 relevant peer-reviewed publications, which were organized into the following categories based on their primary focus: typical Alzheimer's disease, mild cognitive impairment and pre-symptomatic populations; atypical Alzheimer's disease; non-Alzheimer's disease neurodegenerative conditions; head-to-head comparisons with other Tau positron emission tomography tracers; and technical considerations.
Full summary, score breakdown and related studies → Original source
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2023-11-16
Capturing learning curves with the multiday Boston Remote Assessment of Neurocognitive Health (BRANCH): Feasibility, reliability, and validity
41/100 ✓ Peer-reviewed Cognitive tests and assessment Neuropsychology
Key finding: Multiday BRANCH is a feasible, reliable, and valid cognitive measure that may be useful for identifying subtle changes in learning and memory processes in older adults.
Full summary, score breakdown and related studies → Original source
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2023-11-16
Explainable AI-based Alzheimer's prediction and management using multimodal data
53/100 ✓ Peer-reviewed Digital health tools PloS one
Key finding: According to the World Health Organization (WHO), dementia is the seventh leading reason of death among all illnesses and one of the leading causes of disability among the world's elderly people.
Full summary, score breakdown and related studies → Original source
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