Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 20,276–20,300 of 27,380 studies, newest first · page 812 of 1096.
February 2011 25
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2011-02-09
Caregiver support groups in patients with dementia: a meta-analysis
59/100 ✓ Peer-reviewed Caregiving International journal of geriatric psychiatry
Key finding: Support groups benefit caregivers and findings of this meta-analysis serve as immediate guidance for group facilitators. +2 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-08
Adherence to a Mediterranean diet and plasma fatty acids: data from the Bordeaux sample of the Three-City study
57/100 ✓ Peer-reviewed Prevention trials The British journal of nutrition
Key finding: After adjusting for age, sex, energy intake, physical activity, smoking status, BMI, plasma TAG and apoE-ɛ4 genotype, plasma palmitoleic acid was significantly inversely associated with MeDi adherence, whereas plasma DHA, the EPA+DHA index and total n-3 PUFA were positively associated with MeDi adherence. +3 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-08
Epidemiology of Alzheimer disease
54/100 ✓ Peer-reviewed Getting a diagnosis Nature reviews. Neurology
Key finding: The neuropathological hallmarks of the AD brain are diffuse and neuritic extracellular amyloid plaques-which are frequently surrounded by dystrophic neurites-and intracellular neurofibrillary tangles. +4 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-07
Relation of late-life social activity with incident disability among community-dwelling older adults
64/100 ✓ Peer-reviewed Prevention trials The journals of gerontology. Series A, Biological sciences and medical sciences
Key finding: Social activity is associated with a decreased risk of incident disability in activities of daily living, mobility, and instrumental activities of daily living, among community-dwelling older adults. +3 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-07
IScore: a risk score to predict death early after hospitalization for an acute ischemic stroke
51/100 ✓ Peer-reviewed Vascular contributions Circulation
Key finding: Among patients with ischemic stroke, factors identifiable within hours of hospital presentation predicted mortality risk at 30 days and 1 year.
Full summary, score breakdown and related studies → Original source
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2011-02-07
Treatment of advanced Parkinson's disease
37/100 ✓ Peer-reviewed Digital health tools Parkinson's disease
Key finding: These complications include motor fluctuations, dyskinesia, unpredictable or absent response to medications, falls, dysautonomia, dementia, hallucinations, sleep disorders, depression, and psychosis. +4 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-05
The redox basis of epigenetic modifications: from mechanisms to functional consequences
36/100 ✓ Peer-reviewed Genetics Antioxidants & redox signaling
Key finding: Recent research is revealing that redox metabolism is an increasingly important determinant of epigenetic control that may have significant ramifications in both human health and disease.
Full summary, score breakdown and related studies → Original source
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2011-02-04
Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases
36/100 ✓ Peer-reviewed Genetics The Journal of biological chemistry
Key finding: Hypomethylation of CpG islands at intron 1 of the SNCA gene has recently been reported to result in overexpression of α-synuclein in Parkinson disease (PD) and related disorders. +2 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-04
Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study
57/100 ✓ Peer-reviewed Mild cognitive impairment The Lancet. Neurology
Key finding: The cognitive profile was predominantly amnestic and was associated with multiple domains.
Full summary, score breakdown and related studies → Original source
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2011-02-02
Leukocyte telomere length and mortality in the Cardiovascular Health Study
50/100 ✓ Peer-reviewed Vascular contributions The journals of gerontology. Series A, Biological sciences and medical sciences
Key finding: These data weakly corroborate prior findings of associations between LTL and mortality in the elderly. +2 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-02
Retinal vascular caliber and risk of dementia: the Rotterdam study
54/100 ✓ Peer-reviewed Long-term cohort studies Neurology
Key finding: Retinal vessels provide a unique opportunity to study both systemic and cerebrovascular disease. +3 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-01
Association of hospice agency profit status with patient diagnosis, location of care, and length of stay
62/100 ✓ Peer-reviewed End-of-life care JAMA
Key finding: Compared with nonprofit hospice agencies, for-profit hospice agencies had a higher percentage of patients with diagnoses associated with lower-skilled needs and longer lengths of stay. +4 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-01
[Efficacy of cognitive training programs based on new software technologies in patients with Alzheimer-type dementia]
64/100 ✓ Peer-reviewed Prevention trials Psicothema
Key finding: The study aims to assess the efficacy of the Big Brain Academy (BBA), a computerized cognitive training program (CT) based on video games, compared to the Integrated Psychostimulation Program (IPP), a classical CT tool for patients with Alzheimer's disease (AD). +2 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-01
Mediterranean diet and magnetic resonance imaging-assessed cerebrovascular disease
47/100 ✓ Peer-reviewed Prevention trials Annals of neurology
Key finding: Higher adherence to the MeDi is associated with reduced cerebrovascular disease burden. +2 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-01
The frontotemporal dementia mutation R406W blocks tau's interaction with the membrane in an annexin A2-dependent manner
40/100 ✓ Peer-reviewed Disease mechanisms The Journal of cell biology
Key finding: Loss of binding is associated with decreased trapping at the tip of neurites and increased length fluctuations during process growth. +1 more finding
Full summary, score breakdown and related studies → Original source
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2011-02-01
Astrocytes: implications for neuroinflammatory pathogenesis of Alzheimer's disease
40/100 ✓ Peer-reviewed Inflammation and the immune system Current Alzheimer research
Key finding: Neuroinflammation is involved in the onset of several neurodegenerative disorders. +3 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-01
Diagnostic criteria for apathy in clinical practice
57/100 ✓ Peer-reviewed Cognitive tests and assessment International journal of geriatric psychiatry
Key finding: Apathy is an important and distressing behavioural symptom in Alzheimer's disease and in various neuropsychiatric disorders. +3 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-01
Assessment of cerebrospinal fluid (CSF) beta-amyloid (1-42), phosphorylated tau (ptau-181) and total Tau protein in patients with Alzheimer's disease (AD) and other dementia at Siriraj Hospital, Thailand
40/100 ✓ Peer-reviewed Tau biomarkers Journal of the Medical Association of Thailand = Chotmaihet thangphaet
Key finding: The combination of decreased cerebrospinal fluid (CSF) levels of beta-amyloid (1-42) and increased levels of phosphorylated tau (ptau-181) or total tau protein are known to be biomarkers ofAlzheimer's disease (AD). +3 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-01
Review: cerebral microvascular pathology in ageing and neurodegeneration
46/100 ✓ Peer-reviewed Lewy body dementia Neuropathology and applied neurobiology
Key finding: Current evidence suggests that there is decreased vascular density in ageing, Alzheimer's disease and leukoaraiosis, and cerebrovascular dysfunction precedes and accompanies cognitive dysfunction and neurodegeneration.
Full summary, score breakdown and related studies → Original source
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2011-02-01
Cognitive function, dementia and type 2 diabetes mellitus in the elderly
53/100 ✓ Peer-reviewed Risk factors Nature reviews. Endocrinology
Key finding: Type 2 diabetes mellitus is associated with a 1.5-2.5-fold increased risk of dementia. +1 more finding
Full summary, score breakdown and related studies → Original source
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2011-02-01
Trends in antipsychotic use in dementia 1999-2007
54/100 ✓ Peer-reviewed Disparities Archives of general psychiatry
Key finding: In 1999, 17.7% (95% confidence interval [CI], 17.2-18.1) of patients with dementia were using atypical or conventional antipsychotics. +2 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-01
Determinants of medical expenditures in the last 6 months of life
47/100 ✓ Peer-reviewed Disparities Annals of internal medicine
Key finding: It was hypothesized that race or ethnicity, social support, and functional status are independently associated with treatment intensity and controlling for regional characteristics, and that individual characteristics account for a substantial proportion of expenditure variation. +4 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-01
Local amygdala structural differences with 3T MRI in patients with Alzheimer disease
50/100 ✓ Peer-reviewed Brain scans and imaging Neurology
Key finding: Histologic studies show that the amygdala is affected by Alzheimer disease (AD) pathology, and its medial aspect is the most involved.
Full summary, score breakdown and related studies → Original source
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2011-02-01
In vivo fibrillar beta-amyloid detected using [11C]PiB positron emission tomography and neuropathologic assessment in older adults
57/100 ✓ Peer-reviewed Brain scans and imaging Archives of neurology
Key finding: In older adults, variable agreement between in vivo imaging and CERAD NP score was observed. +2 more findings
Full summary, score breakdown and related studies → Original source
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2011-02-01
Review: sporadic cerebral amyloid angiopathy
43/100 ✓ Peer-reviewed Getting a diagnosis Neuropathology and applied neurobiology
Key finding: Cerebral amyloid angiopathy (CAA) may result from focal to widespread amyloid-β protein (Aβ) deposition within leptomeningeal and intracortical cerebral blood vessels. +1 more finding
Full summary, score breakdown and related studies → Original source
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