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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,276–10,300 of 27,380 studies, newest first · page 412 of 1096.

April 2021 25

  1. 2021-04-26

    Dementia with Lewy bodies: emerging drug targets and therapeutics

    ✓ Peer-reviewed Drug development Expert opinion on investigational drugs

    Key finding: Dementia with Lewy bodies (DLB) is characterized by the toxic accumulation of α-synuclein protein inside neural cells; this results in neurodegeneration which is clinically accompanied by behavioral and psychological changes.

    Full summary, score breakdown and related studies → Original source

  2. 2021-04-26

    Role of triggering receptor expressed on myeloid cells 2 (TREM2) in neurodegenerative dementias

    ✓ Peer-reviewed TREM2 and immune genetics The European journal of neuroscience

    Key finding: In the process of underlining the pathogenesis of NDD, growing evidence has related genetic variations in the triggering receptor expressed on myeloid cells 2 (TREM2). +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-04-26

    Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Acta neuropathologica communications

    Key finding: Increasing evidence suggests that neuroinflammation mediated by microglia and astrocytes contributes to disease progression and severity in AD and other neurodegenerative disorders. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-04-26

    Identifying Medicare beneficiaries with dementia

    ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society

    Key finding: Beneficiaries had an average age of 75.3 years and were predominately female (59%) and non-Hispanic whites (93%). +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2021-04-25

    Reduced Synaptic Density in Patients with Lewy Body Dementia: An [11 C]UCB-J PET Imaging Study

    ✓ Peer-reviewed Disease mechanisms Movement disorders : official journal of the Movement Disorder Society

    Key finding: Widespread cortical reduction of synaptic density was documented in a cohort of DLB/PDD subjects using in vivo [11C]UCB-J PET. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-04-23

    Haemodynamic impairment along the Alzheimer's disease continuum

    ✓ Peer-reviewed Tau biomarkers European journal of neurology

    Key finding: The breath-holding index was reduced in the AD continuum and was inversely correlated to CSF amyloid β42 levels. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-04-23

    Remote monitoring technologies in Alzheimer's disease: design of the RADAR-AD study

    ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's research & therapy

    Key finding: Our study is well placed to evaluate the clinical utility of RMT assessments. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2021-04-23

    Serum BDNF as a Potential Biomarker of Alzheimer's Disease: Verification Through Assessment of Serum, Cerebrospinal Fluid, and Medial Temporal Lobe Atrophy

    ✓ Peer-reviewed Biomarkers Frontiers in neurology

    Key finding: Although it has been speculated that brain-derived neurotrophic factor (BDNF) is associated with AD, whether it can be used as a blood biomarker has yet to be determined. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-04-22

    Palliative Care in Advanced Dementia: Comparison of Strategies in Three Countries

    ✓ Peer-reviewed End-of-life care Geriatrics (Basel, Switzerland)

    Key finding: We found that most people with advanced dementia live in nursing homes in the US and The Netherlands, and in the community in Israel. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-04-22

    Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome

    ✓ Peer-reviewed Disease mechanisms Cell

    Key finding: We conclude that functional CMA is essential for neuronal proteostasis through the maintenance of a subset of the proteome with a higher risk of misfolding than the general proteome.

    Full summary, score breakdown and related studies → Original source

  11. 2021-04-22

    Low MoCA performances correlate with suicidal ideation in late-life depression

    ✓ Peer-reviewed Risk factors Psychiatry research

    Key finding: The results show that suicidal patients demonstrated significantly worse performance on the MoCA total score and the delayed recall subtest in comparison to non-suicidal controls. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-04-22

    GLP-1 improves the neuronal supportive ability of astrocytes in Alzheimer's disease by regulating mitochondrial dysfunction via the cAMP/PKA pathway

    ✓ Peer-reviewed Drug development Biochemical pharmacology

    Key finding: Astrocytic mitochondrial abnormalities have been revealed to constitute important pathologies. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2021-04-22

    Usability and User Experience of Cognitive Intervention Technologies for Elderly People With MCI or Dementia: A Systematic Review

    ✓ Peer-reviewed Prevention trials Frontiers in psychology

    Key finding: Measuring usability and UX in cognitive intervention technologies for older adults with MCI or dementia provides an integrated view that can contribute to their development according to the needs and characteristics of the target population.

    Full summary, score breakdown and related studies → Original source

  14. 2021-04-22

    Herpes simplex virus 1 and the risk of dementia: a population-based study

    ✓ Peer-reviewed Long-term cohort studies Scientific reports

    Key finding: Previous studies are inconsistent in their findings regarding the link between HSV1 and dementia, therefore, we investigated how HSV1 relates to cognitive decline and dementia risk using data from a population-based study. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-04-21

    Air Pollution Is Associated with Cognitive Deterioration of Alzheimer's Disease

    ✓ Peer-reviewed Risk factors Gerontology

    Key finding: The PSI was higher in Kaohsiung and compared with Pingtung patients, Kaohsiung patients were exposed to higher average annual concentrations of CO, NO2, PM10, and SO2. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-04-21

    TREM2 expression in the brain and biological fluids in prion diseases

    ✓ Peer-reviewed TREM2 and immune genetics Acta neuropathologica

    Key finding: Its soluble form (sTREM2) results from shedding of the TREM2 ectodomain. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2021-04-21

    Diagnostic and prognostic value of plasma neurofilament light and total-tau in sporadic Creutzfeldt-Jakob disease

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: Among diagnostic groups, highest plasma Nfl and t-tau concentrations were detected in CJD (fold changes of 38 and 18, respectively, compared to HC). +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021-04-21

    A Scoping Review of Cognitive Training in Neurodegenerative Diseases via Computerized and Virtual Reality Tools: What We Know So Far

    ✓ Peer-reviewed Prevention trials Brain sciences

    Key finding: Most prevalent neurodegenerative diseases such as Alzheimer's disease, frontotemporal dementia, Parkinson's disease and multiple sclerosis are heterogeneous in their clinical profiles and underlying pathophysiology, although they typically share the presence of cognitive impairment that worsens significantly during the course of the disease.

    Full summary, score breakdown and related studies → Original source

  19. 2021-04-21

    Dementia is an age-independent risk factor for severity and death in COVID-19 inpatients

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Dementia has been associated with COVID-19 prevalence, but whether this reflects higher infection, older age of patients, or disease severity remains unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-04-20

    Telemedicine and Dementia Care: A Systematic Review of Barriers and Facilitators

    ✓ Peer-reviewed Risk factors Journal of the American Medical Directors Association

    Key finding: Telemedicine is well received among patients and care partners, but successful delivery incorporates support staff and the care partners to navigate technologies. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2021-04-20

    Association of sleep duration in middle and old age with incidence of dementia

    ✓ Peer-reviewed How common it is Nature communications

    Key finding: Sleep dysregulation is a feature of dementia but it remains unclear whether sleep duration prior to old age is associated with dementia incidence. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021-04-20

    Association of sleep duration in middle and old age with incidence of dementia

    ✓ Peer-reviewed Prevention and risk Nature Communications

    Key finding: 7,959 participants followed up to 25 years, 521 dementia cases +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021-04-19

    Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications

    ✓ Peer-reviewed Genetics Molecular psychiatry

    Key finding: Critical neural circuits, biological pathways, and molecular players that go awry in these mental illnesses have been revealed by integrated electrophysiological, optogenetic, biochemical, and transcriptomic studies of PFC.

    Full summary, score breakdown and related studies → Original source

  24. 2021-04-19

    An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank

    ✓ Peer-reviewed Genetics Nature neuroscience

    Key finding: Previously, we found 148 replicated clusters of associations between genetic variants and imaging phenotypes; in this study, we found 692, including 12 on the X chromosome.

    Full summary, score breakdown and related studies → Original source

  25. 2021-04-17

    Treatment of Parkinson's Disease with Cognitive Impairment: Current Approaches and Future Directions

    ✓ Peer-reviewed Treatments Behavioral sciences (Basel, Switzerland)

    Key finding: Cognitive impairment risk in Parkinson's disease increases with disease progression and poses a significant burden to the patients, their families and society.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →