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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,051–19,075 of 27,380 studies, newest first · page 763 of 1096.

December 2012 13

  1. 2012-12-01

    Cognitive deficits and delayed neuronal loss in a mouse model of multiple microinfarcts

    ✓ Peer-reviewed Inflammation and the immune system The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: However, the natural history of these lesions remains largely unexplored. +3 more findings

  2. 2012-12-01

    The neuropathology and neurobiology of traumatic brain injury

    ✓ Peer-reviewed Brain tissue and pathology Neuron

    Key finding: In this Review, we discuss the neuropathology and neural mechanisms associated with TBI, drawing on findings from sports-induced TBI in athletes, in whom acute TBI damages axons and elicits both regenerative and degenerative tissue responses in the brain and in whom repeated concussions may initiate a long-term neurodegenerative process called dementia pugilistica or chronic traumatic encephalopathy (CTE). +2 more findings

  3. 2012-12-01

    Confirmatory factor analysis of the ADNI Neuropsychological Battery

    ✓ Peer-reviewed Long-term cohort studies Brain imaging and behavior

    Key finding: Detailed neuropsychological testing was conducted on all participants. +3 more findings

  4. 2012-12-01

    A composite score for executive functioning, validated in Alzheimer's Disease Neuroimaging Initiative (ADNI) participants with baseline mild cognitive impairment

    ✓ Peer-reviewed Long-term cohort studies Brain imaging and behavior

    Key finding: This study investigates whether a composite executive function measure based on these multiple indicators has better psychometric characteristics than the widely used individual components. +3 more findings

  5. 2012-12-01

    The Alzheimer's Disease Assessment Scale-Cognitive-Plus (ADAS-Cog-Plus): an expansion of the ADAS-Cog to improve responsiveness in MCI

    ✓ Peer-reviewed Cognitive tests and assessment Brain imaging and behavior

    Key finding: The Alzheimer's Disease Assessment Scale cognitive subscale (ADAS-Cog) is widely used in AD, but may be less responsive to change when used in people with mild cognitive impairment (MCI). +3 more findings

  6. 2012-12-01
  7. 2012-12-01

    Development and assessment of a composite score for memory in the Alzheimer's Disease Neuroimaging Initiative (ADNI)

    ✓ Peer-reviewed Cognitive tests and assessment Brain imaging and behavior

    Key finding: We used modern psychometric approaches to analyze longitudinal Rey Auditory Verbal Learning Test (RAVLT, 2 versions), AD Assessment Schedule - Cognition (ADAS-Cog, 3 versions), Mini-Mental State Examination (MMSE), and Logical Memory data to develop ADNI-Mem, a composite memory score. +3 more findings

  8. 2012-12-01

    Alzheimer's Disease in Down Syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's European journal of neurodegenerative disease

    Key finding: A key challenge to adults with Down syndrome (DS) as they age is an increased risk for cognitive decline, dementia, and Alzheimer disease (AD). +1 more finding

  9. 2012-12-01

    Regional white matter hyperintensity volume, not hippocampal atrophy, predicts incident Alzheimer disease in the community

    ✓ Peer-reviewed Caregiving Archives of neurology

    Key finding: The findings highlight the regional specificity of the association of WMHs with AD. +1 more finding

  10. 2012-12-01

    Practical lessons from amyloid immunotherapy trials in Alzheimer disease

    ✓ Peer-reviewed Treatments Current Alzheimer research

    Key finding: More open debates of practical experiences from different trial centres and sponsors are essential for optimizing trial designs and improving conditions for participants. +1 more finding

  11. 2012-12-01

    Personality factors moderate the associations between apolipoprotein genotype and cognitive function as well as late onset Alzheimer disease

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Phenotypic personality dimensions, primarily neuroticism and extraversion, moderate the relationship between APOE [Latin Small Letter Open E]-4 genotype and cognitive outcomes among older adults.

  12. 2012-12-01

    Cognitive outcomes after sertaline treatment in patients with depression of Alzheimer disease

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Treatment with sertraline in patients with dAD is not associated with greater improvement in cognition at week 24 than treatment with placebo. +1 more finding

  13. 2012-12-01

    Investigation of c9orf72 in 4 neurodegenerative disorders

    ✓ Peer-reviewed Genetics Archives of neurology

    Key finding: The C9orf72 expansion is a common cause of ALS and FTLD, but not of AD or PD. +3 more findings

November 2012 12

  1. 2012-11-30

    Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias

    ✓ Peer-reviewed Brain tissue and pathology Brain : a journal of neurology

    Key finding: This study investigated the frequency and severity of atherosclerotic plaques in the circle of Willis in Alzheimer's disease and multiple other neurodegenerative diseases. +3 more findings

  2. 2012-11-30

    Expression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains

    ✓ Peer-reviewed Brain tissue and pathology PloS one

    Key finding: Large-scale genome wide association studies (GWAS) for LOAD have identified 10 novel risk genes: ABCA7, BIN1, CD2AP, CD33, CLU, CR1, EPHA1, MS4A6A, MS4A6E, and PICALM. +3 more findings

  3. 2012-11-29

    Nerve growth factor: from the early discoveries to the potential clinical use

    ✓ Peer-reviewed Brain scans and imaging Journal of translational medicine

    Key finding: NGF plays its trophic role both during development and in adulthood, ensuring the maintenance of phenotypic and functional characteristic of several populations of neurons as well as immune cells. +4 more findings

  4. 2012-11-28

    Deficiency in mural vascular cells coincides with blood-brain barrier disruption in Alzheimer's disease

    ✓ Peer-reviewed Vascular contributions Brain pathology (Zurich, Switzerland)

    Key finding: Moreover, loss of pericytes was associated with BBB breakdown in patients with amyotrophic lateral sclerosis. +2 more findings

  5. 2012-11-28

    Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis

    ✓ Peer-reviewed Genetics Human molecular genetics

    Key finding: Common diseases such as endometriosis (ED), Alzheimer's disease (AD) and multiple sclerosis (MS) account for a significant proportion of the health care burden in many countries. +2 more findings

  6. 2012-11-28

    Does case conferencing for people with advanced dementia living in nursing homes improve care outcomes: evidence from an integrative review?

    ✓ Peer-reviewed End-of-life care International journal of nursing studies

    Key finding: Case conferencing provides opportunities to improve care palliative care outcomes for older people with dementia by engaging family and all relevant internal and external health providers in prospective care planning. +3 more findings

  7. 2012-11-27

    100 years of Lewy pathology

    ✓ Peer-reviewed Brain tissue and pathology Nature reviews. Neurology

    Key finding: In 1912, Fritz Heinrich Lewy identified the protein aggregates that define Parkinson disease (PD) in some brain regions outside the substantia nigra. +4 more findings

  8. 2012-11-27

    Deciphering the mechanism underlying late-onset Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Nature reviews. Neurology

    Key finding: A potential problem underlying these failures is the assumption that the molecular mechanism mediating the genetically determined form of the disease is identical to the one resulting in late-onset AD. +3 more findings

  9. 2012-11-27

    Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons

    ✓ Peer-reviewed Lewy body dementia The Journal of biological chemistry

    Key finding: The accumulation of Tau into aggregates is associated with key pathological events in frontotemporal lobe degeneration (FTD-Tau) and Alzheimer disease (AD). +2 more findings

  10. 2012-11-24

    Patterns of comorbidity and multimorbidity in the oldest old: the Octabaix study

    ✓ Peer-reviewed Risk factors European journal of internal medicine

    Key finding: The large majority of oldest old subjects had multimorbidity. +2 more findings

  11. 2012-11-22

    Prognostic indicators of 6-month mortality in elderly people with advanced dementia: a systematic review

    ✓ Peer-reviewed End-of-life care Palliative medicine

    Key finding: Although the majority of studies agreed that the Functional Assessment Staging 7c criterion was not a reliable predictor of 6-month mortality, we found a lack of prognosticator concordance across the literature. +2 more findings

  12. 2012-11-22

    Long-term anticholinergic use and the aging brain

    ✓ Peer-reviewed Caregiving Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Exposure to medications with severe AC cognitive burden may be a risk factor for developing MCI. +1 more finding

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