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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 20,301–20,325 of 27,380 studies, newest first · page 813 of 1096.

February 2011 6

  1. 2011-02-01
  2. 2011-02-01

    Hearing loss and incident dementia

    ✓ Peer-reviewed Prevention and risk Archives of neurology

    Key finding: Hearing loss is independently associated with incident all-cause dementia. +3 more findings

  3. 2011-02-01

    A new proposal for randomized start design to investigate disease-modifying therapies for Alzheimer disease

    ✓ Peer-reviewed Treatments Clinical trials (London, England)

    Key finding: The greatest advantage of the RSD proposed in this article is its ability to critically address the question on a DM effect.

  4. 2011-02-01

    Preservation of the capacity to appoint a proxy decision maker: implications for dementia research

    ✓ Peer-reviewed Treatments Archives of general psychiatry

    Key finding: A substantial proportion of persons with AD who were thought incapable of consenting to lower-risk or higher-risk studies have preserved capacity for appointing a research proxy. +1 more finding

  5. 2011-02-01

    Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study)

    ✓ Peer-reviewed Treatments Archives of medical science : AMS

    Key finding: The primary planned analyses did not show a significant treatment effect, but were confounded by unexplained variance. +4 more findings

  6. 2011-02-01

    The role of clusterin, complement receptor 1, and phosphatidylinositol binding clathrin assembly protein in Alzheimer disease risk and cerebrospinal fluid biomarker levels

    ✓ Peer-reviewed Genetics Archives of general psychiatry

    Key finding: Furthermore, the CSF biomarker analyses provide a first insight into the potentially predominant pathogenetic mechanism(s) underlying the association between AD risk and PICALM.

January 2011 19

  1. 2011-01-31

    Exercise training increases size of hippocampus and improves memory

    ✓ Peer-reviewed Prevention and risk Proceedings of the National Academy of Sciences of the United States of America

    Key finding: The hippocampus shrinks in late adulthood, leading to impaired memory and increased risk for dementia. +3 more findings

  2. 2011-01-29

    The Montreal Cognitive Assessment and the mini-mental state examination as screening instruments for cognitive impairment: item analyses and threshold scores

    ✓ Peer-reviewed Cognitive tests and assessment Dementia and geriatric cognitive disorders

    Key finding: 135 subjects enrolled in a longitudinal clinicopathologic study were administered the MoCA by a single physician and the MMSE by a trained research assistant. +3 more findings

  3. 2011-01-28

    Predictors of non-invasive ventilation tolerance in amyotrophic lateral sclerosis

    ✓ Peer-reviewed End-of-life care Journal of the neurological sciences

    Key finding: Our study shows that an intensive educational training and adaptation on non-invasive ventilation, when performed in a hospital multidisciplinary setting, increases compliance and tolerance over time, even in those patients with severe bulbar impairment. +1 more finding

  4. 2011-01-27

    Characterizing Alzheimer's disease using a hypometabolic convergence index

    ✓ Peer-reviewed Mild cognitive impairment NeuroImage

    Key finding: HCIs were significantly different in the probable AD, MCI converter, MCI stable and NC groups (p=9e-17) and correlated with clinical disease severity. +1 more finding

  5. 2011-01-26

    The effect of cognitive impairment on the accuracy of the presenting complaint and discharge instruction comprehension in older emergency department patients

    ✓ Peer-reviewed Risk factors Annals of emergency medicine

    Key finding: Proportional odds logistic regression was performed to determine whether cognitive impairment was associated with presenting complaint accuracy and discharge instruction comprehension. +4 more findings

  6. 2011-01-26

    Peripheral insulin-sensitizer drug metformin ameliorates neuronal insulin resistance and Alzheimer's-like changes

    ✓ Peer-reviewed Drug development Neuropharmacology

    Key finding: Currently there is widening recognition that AD is closely associated with impaired insulin signaling and glucose metabolism in brain, suggesting it to be a brain-specific form of diabetes and so also termed as "type 3 diabetes". +3 more findings

  7. 2011-01-26

    Impaired regulation of synaptic actin cytoskeleton in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Brain research reviews

    Key finding: Numerous studies analyzing human postmortem tissue, animal models and cellular paradigms indicate that AD pathology has a deleterious effect on the pathways governing actin cytoskeleton stability.

  8. 2011-01-26

    The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies

    ✓ Peer-reviewed Risk factors BMC medical genomics

    Key finding: The eMERGE (electronic MEdical Records and GEnomics) Network is an NHGRI-supported consortium of five institutions to explore the utility of DNA repositories coupled to Electronic Medical Record (EMR) systems for advancing discovery in genome science. eMERGE also includes a special emphasis on the ethical, legal and social issues related to these endeavors. +1 more finding

  9. 2011-01-25

    CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease

    ✓ Peer-reviewed Inflammation and the immune system Journal of neuroinflammation

    Key finding: Parkinson's disease is characterized by a progressive loss of dopaminergic neurons in the substantia nigra. +3 more findings

  10. 2011-01-25

    Naturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanism

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Alterations in protein homeostasis and mTOR activity and signaling have been reported in several neurodegenerative disorders, including Alzheimer disease (AD); however, the causes of such deregulations remain elusive. +3 more findings

  11. 2011-01-25
  12. 2011-01-21

    Whole transcriptome sequencing reveals gene expression and splicing differences in brain regions affected by Alzheimer's disease

    ✓ Peer-reviewed Genetics PloS one

    Key finding: Recent studies strongly indicate that aberrations in the control of gene expression might contribute to the initiation and progression of Alzheimer's disease (AD). +4 more findings

  13. 2011-01-21

    Neuropsychiatric and cognitive profile of patients with DSM-IV delirium referred to an old age psychiatry consultation-liaison service

    ✓ Peer-reviewed End-of-life care International psychogeriatrics

    Key finding: Delirium is a complex neuropsychiatric syndrome with generalized cognitive impairment and disproportionate inattention. +2 more findings

  14. 2011-01-21

    Depression and hypothalamic-pituitary-adrenal activation: a quantitative summary of four decades of research

    ✓ Peer-reviewed Risk factors Psychosomatic medicine

    Key finding: The current study suggests that the degree of HPA hyperactivity can vary considerably across patient groups. +4 more findings

  15. 2011-01-21

    Assessing end-of-life preferences for advanced dementia in rural patients using an educational video: a randomized controlled trial

    ✓ Peer-reviewed Disparities Journal of palliative medicine

    Key finding: Rural subjects with higher health literacy were more likely to want comfort care compared to those with lower levels of health literacy. +4 more findings

  16. 2011-01-20

    Family caregiving in dementia: the Asian perspective of a global problem

    ✓ Peer-reviewed Caregiving Dementia and geriatric cognitive disorders

    Key finding: A full understanding of the specific way that culture could influence family caregivers' burdens may play an important part in the development of a holistic model for family-centered care. +4 more findings

  17. 2011-01-20

    REST regulates DYRK1A transcription in a negative feedback loop

    ✓ Peer-reviewed Down syndrome and Alzheimer's The Journal of biological chemistry

    Key finding: Here, we found that REST can activate DYRK1A transcription via a neuron-restrictive silencer element at bp -833 to -815 of human DYRK1A promoter. +2 more findings

  18. 2011-01-19

    Beneficial effect of repetitive transcranial magnetic stimulation combined with cognitive training for the treatment of Alzheimer's disease: a proof of concept study

    ✓ Peer-reviewed Brain scans and imaging Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: Primary objectives were average improvement of Alzheimer Disease Assessment Scale-Cognitive (ADAS-cog) and Clinical Global Impression of Change (CGIC) (after 6 weeks and 4.5 months, compared to baseline).

  19. 2011-01-19

    Classification of Alzheimer disease, mild cognitive impairment, and normal cognitive status with large-scale network analysis based on resting-state functional MR imaging

    ✓ Peer-reviewed Brain scans and imaging Radiology

    Key finding: LSN analysis revealed that interconnectivity patterns of brain regions can be used to classify subjects with AD, those with aMCI, and CN subjects. +4 more findings

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