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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,301–19,325 of 27,380 studies, newest first · page 773 of 1096.

August 2012 18

  1. 2012-08-02

    The genetics and neuropathology of amyotrophic lateral sclerosis

    ✓ Peer-reviewed Lewy body dementia Acta neuropathologica

    Key finding: For several years, only one gene was known to have a role in ALS pathogenesis, SOD1. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2012-08-02

    Rates of decline in Alzheimer disease decrease with age

    ✓ Peer-reviewed Brain scans and imaging PloS one

    Key finding: These results imply that the phenotypic expression of AD is relatively mild in individuals older than approximately 85 years, and this may affect the ability to distinguish AD from normal aging in the very old. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2012-08-01

    Two new combination pediatric vaccines advancing to use in infants

    ✓ Peer-reviewed Clinical trials Human vaccines & immunotherapeutics

    Key finding: Two new combination pediatric vaccines advancing to use in infants Oncolytic viruses successfully delivered intravenously Cuba eliminates hepatitis B among minors under 15 Alzheimer's vaccine trial a success Study: Shingles vaccine safe for patients on immune-suppressing drugs Therapeutic cancer vaccine against metastatic renal cell carcinoma enters Phase 3 Pfizer’s Men B vaccine shows promise in Phase 2 Biovest initiates formal regulatory approval process for BiovaxID in Europe

    Full summary, score breakdown and related studies → Original source

  4. 2012-08-01

    Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update

    ✓ Peer-reviewed Getting a diagnosis Biomarkers in medicine

    Key finding: Cerebrospinal fluid (CSF) biomarkers can be a good tool for early diagnosis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2012-08-01

    Tau alternative splicing in familial and sporadic tauopathies

    ✓ Peer-reviewed Disease mechanisms Biochemical Society transactions

    Key finding: Advanced RNA analysis methods have suggested that levels of exon 10-containing MAPT mRNA are elevated in Alzheimer's disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2012-08-01

    TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways

    ✓ Peer-reviewed Brain tissue and pathology The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Mutations in the progranulin gene (GRN) causing impaired production or secretion of progranulin are a common Mendelian cause of FTLD-TDP; additionally, common variants at chromosome 7p21 in the uncharacterized gene TMEM106B were recently linked by genome-wide association to FTLD-TDP with and without GRN mutations. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2012-08-01

    The integration of frailty into clinical practice: preliminary results from the Gérontopôle

    ✓ Peer-reviewed Cognitive tests and assessment The journal of nutrition, health & aging

    Key finding: Disability is commonly considered as an irreversible condition of advanced age. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2012-08-01

    Progression of Alzheimer's disease as measured by Clinical Dementia Rating Sum of Boxes scores

    ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: This study examined rates of dementia progression as ascertained by the Clinical Dementia Rating Sum of Boxes (CDR-SB) for symptomatic Alzheimer's disease (sAD), and assessed participant characteristics as predictors of CDR-SB progression. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2012-08-01

    Comparison of cerebrospinal fluid levels of tau and Aβ 1-42 in Alzheimer disease and frontotemporal degeneration using 2 analytical platforms

    ✓ Peer-reviewed Tau biomarkers Archives of neurology

    Key finding: Cerebrospinal fluid values of total tau (T-tau) and β-amyloid 1-42 (Aβ 1-42) obtained using the Innotest enzyme-linked immunosorbent assay were transformed using a linear regression model to equivalent values obtained using the INNO-BIA AlzBio3 (xMAP; Luminex) assay. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2012-08-01

    Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Here we investigate whether APP contributes to ER Ca²⁺ homeostasis and whether ER Ca²⁺ could in turn influence Aβ production. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2012-08-01

    [Function of intersectin in endocytosis and exocytosis]

    ✓ Peer-reviewed Down syndrome and Alzheimer's Sheng li xue bao : [Acta physiologica Sinica]

    Key finding: Intersectin is an evolutionarily conserved multifunctional adaptor protein with multifunctional domains. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2012-08-01

    Epidemiology of Alzheimer disease

    ✓ Peer-reviewed How common it is Cold Spring Harbor perspectives in medicine

    Key finding: The etiology of Alzheimer disease remains unclear, but it is likely to be the result of both genetic and environmental factors.

    Full summary, score breakdown and related studies → Original source

  13. 2012-08-01

    A mutation in APP protects against Alzheimer's disease and age-related cognitive decline

    ✓ Peer-reviewed How common it is Nature

    Key finding: Here, to search for low-frequency variants in the amyloid-β precursor protein (APP) gene with a significant effect on the risk of Alzheimer's disease, we studied coding variants in APP in a set of whole-genome sequence data from 1,795 Icelanders. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2012-08-01

    Plasma long-chain omega-3 fatty acids and atrophy of the medial temporal lobe

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: The long-chain ω-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are potential candidates for interventions to delay Alzheimer disease (AD), but evidence from clinical studies is mixed.

    Full summary, score breakdown and related studies → Original source

  15. 2012-08-01

    Cognitive impairment in patients with Parkinson's disease: diagnosis, biomarkers, and treatment

    ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology

    Key finding: The underlying mechanisms of dementia associated with Parkinson's disease are only partly known and no mechanism-based treatments are available. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2012-08-01

    The impact of inflammation on cognitive function in older adults: implications for healthcare practice and research

    ✓ Peer-reviewed Prevention and risk The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses

    Key finding: Accumulating evidence suggests that levels of inflammation, an immune response, increase with age throughout the body and the brain. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2012-08-01

    Effect of immunotherapy with bapineuzumab on cerebrospinal fluid biomarker levels in patients with mild to moderate Alzheimer disease

    ✓ Peer-reviewed Treatments Archives of neurology

    Key finding: Cerebrospinal fluid biomarkers may be useful to monitor the effects of novel disease-modifying anti-Aβ drugs in clinical trials. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2012-08-01

    Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Four plasma analytes were consistently associated with the diagnosis of very mild dementia/MCI/AD in 3 independent clinical cohorts. +2 more findings

    Full summary, score breakdown and related studies → Original source

July 2012 7

  1. 2012-07-30

    Dysphagia in the elderly: management and nutritional considerations

    ✓ Peer-reviewed Clinical safety Clinical interventions in aging

    Key finding: Though increasing age facilitates subtle physiologic changes in swallow function, age-related diseases are significant factors in the presence and severity of dysphagia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2012-07-28

    Cognitive correlates of cerebrospinal fluid biomarkers in frontotemporal dementia

    ✓ Peer-reviewed Tau biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: After correction for age, sex, and education, CSF tau levels were found to be negatively related to the Visual Association Test (standardized β = -0.3, P < .05), whereas CSF Aβ1-42 levels were found to be positively related to the Mini-Mental State Examination (β = 0.3, P < .05), the frontal assessment battery (β = 0.5, P < .05), and digit span backwards test (β = 0.3, P = .01). +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2012-07-27

    Population based study on patients with traumatic brain injury suggests increased risk of dementia

    ✓ Peer-reviewed Costs and economics Journal of neurology, neurosurgery, and psychiatry

    Key finding: The findings of this study suggest an increased risk of dementia among individuals with TBI. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2012-07-27

    Health and aging in elderly farmers: the AMI cohort

    ✓ Peer-reviewed Disparities BMC public health

    Key finding: AMI is the first French longitudinal study on health and aging set up in a population of elderly farmers living in rural area through a multidisciplinary approach. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2012-07-26

    From mitochondrial dysfunction to amyloid beta formation: novel insights into the pathogenesis of Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Molecular neurobiology

    Key finding: Taken together, a vicious cycle is initiated that originates from mitochondrial dysfunction, implying that AD can be viewed as an age-associated mitochondrial disorder.

    Full summary, score breakdown and related studies → Original source

  6. 2012-07-26

    In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson's disease

    ✓ Peer-reviewed Inflammation and the immune system Parkinsonism & related disorders

    Key finding: Reactive microgliosis, hallmark of neuroinflammation, may contribute to neuronal degeneration, as shown in several neurodegenerative diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2012-07-25

    Carotid atherosclerosis and 10-year changes in cognitive function

    ✓ Peer-reviewed Risk factors Atherosclerosis

    Key finding: In this population-based longitudinal study, carotid IMT was associated with a higher risk of developing cognitive impairment during the 10-year follow-up, and was associated with poorer performance in a test of executive function 10 years later. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →