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Mild cognitive impairment in moderate to severe COPD: a preliminary study
Villeneuve S, Pepin V, Rahayel S, Bertrand JA, de Lorimier M, Rizk A, Desjardins C, Parenteau S et al.. Chest, 2012-12-01
Topic: Risk, prevention and care in population studies
Background Cognitive impairment is a frequent feature of COPD. However, the proportion of patients with COPD with mild cognitive impairment (MCI) is still unknown, and no screening test has been validated to date for detecting MCI in this population. The goal of this study was to determine the frequency and subtypes of MCI in patients with COPD and to assess the validity of two cognitive screening tests, the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA), in detecting MCI in patients with COPD.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Villeneuve, S., Pepin, V., Rahayel, S., Bertrand, J. A., de Lorimier, M., Rizk, A., et al. (2012). Mild cognitive impairment in moderate to severe COPD: a preliminary study. Chest. https://doi.org/10.1378/chest.11-3035
Vancouver
Villeneuve S, Pepin V, Rahayel S, Bertrand JA, de Lorimier M, Rizk A, et al. Mild cognitive impairment in moderate to severe COPD: a preliminary study. Chest. 2012. doi:10.1378/chest.11-3035. PMID: 23364388.
BibTeX
@article{villeneuve2012-23364388,
author = {Villeneuve, S. and Pepin, V. and Rahayel, S. and Bertrand, J. A. and de Lorimier, M. and Rizk, A. and Desjardins, C. and Parenteau, S. and others},
title = {{Mild cognitive impairment in moderate to severe COPD: a preliminary study}},
journal = {Chest},
year = {2012},
doi = {10.1378/chest.11-3035},
pmid = {23364388},
url = {https://doi.org/10.1378/chest.11-3035}
}
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Key findings
- However, the proportion of patients with COPD with mild cognitive impairment (MCI) is still unknown, and no screening test has been validated to date for detecting MCI in this population.
- The goal of this study was to determine the frequency and subtypes of MCI in patients with COPD and to assess the validity of two cognitive screening tests, the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA), in detecting MCI in patients with COPD.
- Methods Forty-five patients with moderate to severe COPD and 50 healthy control subjects underwent a comprehensive neuropsychologic assessment using standard MCI criteria.
- Receiver operating characteristic curves were obtained to assess the validity of the MMSE and the MoCA to detect MCI in patients with COPD.
Why it matters
This preliminary study of 45 patients with moderate to severe COPD examined how common mild cognitive impairment was and whether the MMSE or MoCA could detect it. It is a small screening study and does not test any treatment, cure, or prevention for Alzheimer's disease.
Study details
- Study designlongitudinal study
- Evidence strengthModerate
How this study scored 54/100
Published in a peer-reviewed journal, and it is a longitudinal study following the same people over time. Scored zero for sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Chest) |
| Journal's citation record | 3 / 4 | CHEST Journal: journal h-index 407 (OpenAlex, 2026-10-29) |
| Study design | 7 / 12 | A longitudinal study following the same people over time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2012 — within 20 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 178 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 11.1 citations a year over 16 year(s) since 2012 |
| Impact for its field and year | 3 / 6 | Cited 7.4× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 3 other studies in this library |
| Still being cited | 2 / 4 | Cited 31 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Jean‐François Gagnon: h-index 62 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Université de Montréal: institution h-index 1,020 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 6 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 23364388) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 54 / 100 | — |
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