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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 25,301–25,325 of 27,380 studies, newest first · page 1013 of 1096.

January 2001 8

  1. 2001-01-01

    Thiamine for Alzheimer's disease

    ✓ Peer-reviewed Treatments The Cochrane database of systematic reviews

    Key finding: The cross-over studies did not report results from the first phase. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2001-01-01

    Statins for the reduction of risk of Alzheimer's disease

    ✓ Peer-reviewed Treatments The Cochrane database of systematic reviews

    Key finding: There were no randomized trials found in the search. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2001-01-01

    Piracetam for dementia or cognitive impairment

    ✓ Peer-reviewed Treatments The Cochrane database of systematic reviews

    Key finding: Selection criteria All unconfounded trials specified as randomized in which treatment with piracetam was administered for more than a day and compared with placebo in patients with dementia of Alzheimer type, vascular dementia,or mixed vascular and Alzheimer's disease, or unclassified dementia, or cognitive impairment not fulfilling the criteria for dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2001-01-01

    Statins for the prevention of Alzheimer's disease

    ✓ Peer-reviewed Treatments The Cochrane database of systematic reviews

    Key finding: There were no randomized trials found in the search. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2001-01-01

    Physostigmine for Alzheimer's disease

    ✓ Peer-reviewed Treatments The Cochrane database of systematic reviews

    Key finding: Studies conducted more than 20 years ago suggested that physostigmine could improve memory in people with or without dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2001-01-01

    A pilot randomized trial of carbamazepine for behavioral symptoms in treatment-resistant outpatients with Alzheimer disease

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Overall, carbamazepine showed modest clinical benefit in these subjects, who had not responded to antipsychotics, and particular benefit for hostility.

    Full summary, score breakdown and related studies → Original source

  7. 2001-01-01

    Categorizing genetic tests to identify their ethical, legal, and social implications

    ✓ Peer-reviewed Genetics American journal of medical genetics

    Key finding: Taken together, these examples suggest that genetic tests can be categorized by a joint consideration of clinical validity and availability of effective treatment for persons who test positive.

    Full summary, score breakdown and related studies → Original source

  8. 2001-01-01

    Neuropathological analysis of pathological forms of astroglia in Wilson's disease

    ✓ Peer-reviewed Biomarkers Folia neuropathologica

    Key finding: On conventional staining, each of the studied abnormal cell types retained common morphological characteristics of astroglia, and concurrently demonstrated its own distinctive features, specific only for a given cell type. +4 more findings

    Full summary, score breakdown and related studies → Original source

December 2000 17

  1. 2000-12-12

    Hippocampal and cortical atrophy predict dementia in subcortical ischemic vascular disease

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Among the three lacune groups, severity of cognitive impairment correlated with atrophy of the hippocampus and cortical gray matter, but not with any lacune measure. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2000-12-01

    Interleukin 1 in the brain: biology, pathology and therapeutic target

    ✓ Peer-reviewed Risk factors Trends in neurosciences

    Key finding: In normal brain the IL-1 system is expressed at low levels and is upregulated rapidly in response to local or peripheral insults. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2000-12-01

    Site-directed antisense oligonucleotide decreases the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice

    ✓ Peer-reviewed Drug development Peptides

    Key finding: We found that intracerebroventricular (ICV) administration of antibody with either of two AOs directed at the midregion of Abeta improved acquisition and retention in a footshock avoidance paradigm, whereas two AOs directed more toward the C-terminal, a random AO, and vehicle were without effect. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2000-12-01

    Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice

    ✓ Peer-reviewed Drug development The Journal of biological chemistry

    Key finding: Phosphorylated protein tau migrates slower during electrophoretic separation and is revealed by phosphorylation-dependent anti-tau antibodies in Western blot analysis. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2000-12-01

    A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE Nature

    Key finding: Much evidence indicates that abnormal processing and extracellular deposition of amyloid-beta peptide (A beta), a proteolytic derivative of the beta-amyloid precursor protein (betaAPP), is central to the pathogenesis of Alzheimer's disease (reviewed in ref. 1).

    Full summary, score breakdown and related studies → Original source

  6. 2000-12-01

    Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

    ✓ Peer-reviewed Genetics The Journal of clinical investigation

    Key finding: As compared to adult wild-type mice, clearance was significantly reduced in young and old apolipoprotein E (apoE) knockout mice, and in old wild-type mice. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2000-12-01

    Early DAT is distinguished from aging by high-dimensional mapping of the hippocampus. Dementia of the Alzheimer type

    ✓ Peer-reviewed Hippocampus size on brain scans Neurology

    Key finding: Assessments of hippocampal volume and shape derived from HDBM may be useful in distinguishing early DAT from healthy aging. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2000-12-01

    Assessment of pain in cognitively impaired older adults: a comparison of pain assessment tools and their use by nonprofessional caregivers

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: The mean age of the CI subjects was 83, and 83% were women. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2000-12-01

    Cell death or synaptic loss in Alzheimer disease

    ✓ Peer-reviewed Disease mechanisms Journal of neuropathology and experimental neurology

    Key finding: It is an erroneous but common assumption that loss of neuronal perikarya causes the cognitive change in Alzheimer disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2000-12-01

    Neurotoxicity of advanced glycation end-products for cultured cortical neurons

    ✓ Peer-reviewed Disease mechanisms Journal of neuropathology and experimental neurology

    Key finding: The structural epitope designated AGE-2 was found to have the greatest cytopathic effect and the neurotoxicity of AGE-2 was neutralized by the addition of an anti-AGE-2-specific antibody, but not by other types of anti-AGE antibodies. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2000-12-01

    Changes in cognitive functioning following treatment of late-life depression

    ✓ Peer-reviewed Brain tissue and pathology The American journal of psychiatry

    Key finding: Knowledge of the relationship between various clinical characteristics and cognitive functioning is advancing, but little is known about the cognitive response to treatment for geriatric depression. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2000-12-01

    Subclinical hyperthyroidism and the risk of dementia. The Rotterdam study

    ✓ Peer-reviewed Long-term cohort studies Clinical endocrinology

    Key finding: Thyroid status was measured at baseline (1990-93), through assessment of serum antibodies to thyroid peroxidase (TPO-Abs, positive: >10 IU/ml), serum TSH levels, and when TSH was abnormal ( 4.0 mU/l), serum thyroxin levels (T4). +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2000-12-01

    The FAB: a Frontal Assessment Battery at bedside

    ✓ Peer-reviewed Lewy body dementia Neurology

    Key finding: The designed battery consists of six subtests exploring the following: conceptualization, mental flexibility, motor programming, sensitivity to interference, inhibitory control, and environmental autonomy.

    Full summary, score breakdown and related studies → Original source

  14. 2000-12-01

    Sequence of cognitive decline in dementia in adults with Down's syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of intellectual disability research : JIDR

    Key finding: In a longitudinal study in which all participants were healthy at the time of their entry into the study, the present authors compared the amount of decline on the subtests of the WISC-R to determine the sequence of cognitive decline associated with varying stages of dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2000-12-01

    Cognitive dysfunction in older subjects with diabetes mellitus: impact on diabetes self-management and use of care services. All Wales Research into Elderly (AWARE) Study

    ✓ Peer-reviewed Risk factors Diabetes research and clinical practice

    Key finding: Routine screening of cognition in older subjects with diabetes is recommended. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2000-12-01

    Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment

    ✓ Peer-reviewed Risk factors Lipids

    Key finding: Fatty acid differences, including docosahexaenoic acid (DHA; 22:6n-3) have been shown in the brains of Alzheimer's patients (AD) as compared with normal age-matched individuals. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2000-12-01

    A brief cognitive test battery to differentiate Alzheimer's disease and frontotemporal dementia

    ✓ Peer-reviewed How common it is Neurology

    Key finding: The ACE is a brief and reliable bedside instrument for early detection of dementia, and offers a simple objective index to differentiate AD and FTD in mildly demented patients. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →