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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,076–19,100 of 27,380 studies, newest first · page 764 of 1096.

November 2012 25

  1. 2012-11-21

    A qualitative study: professionals' experiences of advance care planning in dementia and palliative care, 'a good idea in theory but ...'

    ✓ Peer-reviewed End-of-life care Palliative medicine

    Key finding: This study has identified the professional, organisational and legal factors that influence advance care planning implementation; professional training should target these specific areas. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2012-11-21

    Cognitive impairment in Parkinson disease: impact on quality of life, disability, and caregiver burden

    ✓ Peer-reviewed Caregiving Journal of geriatric psychiatry and neurology

    Key finding: Both quality of life and caregiver burden were similar in the 2 groups without dementia but were significantly different in those with PDD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2012-11-20

    Multiple effects of physical activity on molecular and cognitive signs of brain aging: can exercise slow neurodegeneration and delay Alzheimer's disease?

    ✓ Peer-reviewed Prevention and risk Molecular psychiatry

    Key finding: This paper reviews studies that have explored the relationship between physical activity and cognitive function, cognitive decline, AD/dementia risk and AD-associated biomarkers and processes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2012-11-19

    Zolpidem is independently associated with increased risk of inpatient falls

    ✓ Peer-reviewed Clinical safety Journal of hospital medicine

    Key finding: Zolpidem use was a strong, independent, and potentially modifiable risk factor for inpatient falls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2012-11-19

    Amyloid-β Imaging with Pittsburgh Compound B and Florbetapir: Comparing Radiotracers and Quantification Methods

    ✓ Peer-reviewed Brain scans and imaging Journal of Nuclear Medicine

    PiB and florbetapir retention ratios were strongly associated in the same individuals, and this relationship was consistent across several data analysis methods, despite scan-rescan intervals of more than a year.

    Full summary, score breakdown and related studies → Original source

  6. 2012-11-19

    The Impact of Semantic Dementia on Everyday Actions: Evidence from an Ecological Study

    ✓ Peer-reviewed Risk factors Journal of the International Neuropsychological Society

    Key finding: In theory, semantic memory may trigger and support the execution of everyday activities. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2012-11-17

    Selecting the best instruments to measure quality of end-of-life care and quality of dying in long term care

    ✓ Peer-reviewed End-of-life care Journal of the American Medical Directors Association

    Key finding: We recommend the EOLD-SWC to measure QOC, and the EOLD-CAD and MSSE to measure QOD in populations with dementia and in mixed long term care populations of nursing home or residential care home/assisted living residents, because they performed best in both countries. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2012-11-16

    The prevalence and course of neuropsychiatric symptoms in nursing home patients with dementia: a systematic review

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Medical Directors Association

    Key finding: This review confirms that clinically significant NPSs are common in NH patients with dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2012-11-16

    Impact of molecular imaging on the diagnostic process in a memory clinic

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: [(11)C]PIB scans were positive in 40 of 66 (61%) patients with a clinical diagnosis of Alzheimer's disease (AD), 5 of 18 (28%) patients with frontotemporal dementia (FTD), 4 of 5 (80%) patients with Lewy body dementia, and 3 of 10 (30%) patients with other dementias. [(18)F]FDG uptake patterns matched the clinical diagnosis in 38 of 66 (58%) of AD patients, and in 6 of 18 (33%) FTD patients. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2012-11-15

    Epidemiology of dementias and Alzheimer's disease

    ✓ Peer-reviewed Clinical safety Archives of medical research

    Key finding: There are a substantial number of people with dementia worldwide and these numbers will continue to increase mainly in LMIC, producing a wide range of impacts.

    Full summary, score breakdown and related studies → Original source

  11. 2012-11-15

    Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: The role of glycogen synthase kinase-3 (GSK-3) in Alzheimer disease pathogenesis has been debated. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2012-11-14

    Mild cognitive impairment: cerebrospinal fluid tau biomarker pathologic levels and longitudinal changes in white matter integrity

    ✓ Peer-reviewed Tau biomarkers Radiology

    Key finding: Thirty patients with MCI and nonpathologic CSF total tau levels, nine patients with MCI and pathologic CSF total tau levels, and 16 age-matched healthy control subjects underwent diffusion-tensor imaging at baseline and after a mean follow-up of 2.6 years ± 0.54 (standard deviation), with range of 1.58-3.98 years. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2012-11-14

    Variant of TREM2 associated with the risk of Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics The New England journal of medicine

    Key finding: Sequence variants, including the ε4 allele of apolipoprotein E, have been associated with the risk of the common late-onset form of Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2012-11-14

    TREM2 variants in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics The New England journal of medicine

    Key finding: Homozygous loss-of-function mutations in TREM2, encoding the triggering receptor expressed on myeloid cells 2 protein, have previously been associated with an autosomal recessive form of early-onset dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2012-11-13

    The neural basis of semantic cognition: converging evidence from neuropsychology, neuroimaging and TMS

    ✓ Peer-reviewed Vascular contributions Cortex; a journal devoted to the study of the nervous system and behavior

    Key finding: Recent studies suggest that a complex, distributed neural network underpins semantic cognition. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2012-11-13

    APP mutations in the Aβ coding region are associated with abundant cerebral deposition of Aβ38

    ✓ Peer-reviewed Down syndrome and Alzheimer's Acta neuropathologica

    Key finding: Immunohistochemistry, confocal microscopy, immunoelectron microscopy, immunoprecipitation and the electrophoresis separation of low molecular weight aggregates revealed that Aβ38 accumulates consistently in the brains of patients carrying APP mutations in the Aβ coding region, but was not detected in the patients with APP mutations outside the Aβ domain, in the patients with presenilin mutations or in subjects with Down syndrome. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2012-11-12

    Structures of human acetylcholinesterase in complex with pharmacologically important ligands

    ✓ Peer-reviewed Treatments Journal of medicinal chemistry

    Key finding: Human acetylcholinesterase (AChE) is a significant target for therapeutic drugs.

    Full summary, score breakdown and related studies → Original source

  18. 2012-11-10

    Translation and cross-cultural adaptation of a family booklet on comfort care in dementia: sensitive topics revised before implementation

    ✓ Peer-reviewed End-of-life care Journal of medical ethics

    Key finding: Providing artificial feeding and fluids and discussing euthanasia may be particularly sensitive topics, and guidance on these subjects needs careful consideration of ethical aspects and possible adaptations to local standards and practice.

    Full summary, score breakdown and related studies → Original source

  19. 2012-11-10

    Meta-analysis based SVM classification enables accurate detection of Alzheimer's disease across different clinical centers using FDG-PET and MRI

    ✓ Peer-reviewed Long-term cohort studies Psychiatry research

    Key finding: To validate this approach for the most frequent dementia syndrome AD, and to test its applicability to multicenter data, we randomly extracted FDG-PET and MRI data of 28 AD patients and 28 healthy control subjects from the database provided by the Alzheimer's Disease Neuroimaging Initiative (ADNI) and compared them to data of 21 patients with AD and 13 control subjects from our own Leipzig cohort. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2012-11-09

    Cerebral amyloid angiopathy

    ✓ Peer-reviewed Vascular contributions The neuroradiology journal

    Key finding: Magnetic resonance imaging was requested due to the presence of small hyperdense lesions on CT, and revealed multiple diffuse hypodense parenchymal lesions with hemosiderin deposits, indicative of cerebral amyloid angiopathy. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2012-11-09

    Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation

    ✓ Peer-reviewed Vascular contributions Fluids and barriers of the CNS

    Key finding: The barrier properties of these specialized endothelial cells notably depend on tight junctions (TJs) between adjacent cells: TJs are dynamic structures consisting of a number of transmembrane and membrane-associated cytoplasmic proteins, which are assembled in a multimolecular complex and acting as a platform for intracellular signaling. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2012-11-09

    Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Acta neuropathologica

    Key finding: Importantly, we found that this PS1 conformational shift is associated with amyloid pathology and precedes amyloid-β deposition in the brain. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2012-11-09

    Hippocampal volume varies with educational attainment across the life-span

    ✓ Peer-reviewed Hippocampus size on brain scans Frontiers in human neuroscience

    Key finding: Socioeconomic disparities-and particularly differences in educational attainment-are associated with remarkable differences in cognition and behavior across the life-span. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2012-11-09

    Reduced hippocampal volume in healthy young ApoE4 carriers: an MRI study

    ✓ Peer-reviewed Hippocampus size on brain scans PloS one

    Key finding: The E4 allele of the ApoE gene has consistently been shown to be related to an increased risk of Alzheimer's disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2012-11-09

    Application of Resource Utilization in Dementia (RUD) instrument in a global setting

    ✓ Peer-reviewed Caregiving Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Several minor changes were made to the RUD instrument to improve the accuracy and precision of the data while maintaining comparability with the original version and reflecting current medical practice.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →