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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,176–19,200 of 27,380 studies, newest first · page 768 of 1096.

October 2012 16

  1. 2012-10-01

    The role of DNA methylation in aging, rejuvenation, and age-related disease

    ✓ Peer-reviewed Genetics Rejuvenation research

    Key finding: These changes in the epigenetic landscape represent potential disease biomarkers and are thought to contribute to age-related pathologies, such as cancer, osteoarthritis, and neurodegeneration. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2012-10-01

    Transthyretin decrease in plasma of MCI and AD patients: investigation of mechanisms for disease modulation

    ✓ Peer-reviewed Biomarkers Current Alzheimer research

    Key finding: We investigated TTR levels in plasma samples from 55 patients with mild-cognitive impairment (MCI), 56 patients with AD and 41 non-demented controls, and found that TTR is decreased in both MCI and AD groups, suggesting that TTR might be used for staging early AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2012-10-01

    The quality of advanced dementia care in the nursing home: the role of special care units

    ✓ Peer-reviewed End-of-life care Medical care

    Key finding: Residence in an SCU is associated with some, but not all, markers of better quality end-of-life care among nursing home residents with advanced dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2012-10-01

    The impact of autonomic dysfunction on survival in patients with dementia with Lewy bodies and Parkinson's disease with dementia

    ✓ Peer-reviewed Clinical safety PloS one

    Key finding: According to our findings, the identification of autonomic dysfunction seems to be of great importance in clinical practice, not only to avoid falls and other complications, but also as a possible predictor of survival. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2012-10-01

    Mild cognitive impairment as a predictor of falls in community-dwelling older people

    ✓ Peer-reviewed Clinical safety The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Of the participants, 342 (81.6%) had normal cognitive functioning, 58 (13.8%) had nonamnestic MCI, and 19 (4.5%) had amnestic MCI. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2012-10-01

    Pathologic accumulation of α-synuclein and Aβ in Parkinson disease patients with dementia

    ✓ Peer-reviewed Disease mechanisms Archives of neurology

    Key finding: Dementia associated with PD has 2 major pathologic subgroups: neocortical synucleinopathy and neocortical synucleinopathy with Aβ deposition. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2012-10-01

    Dementia resulting from traumatic brain injury: what is the pathology?

    ✓ Peer-reviewed Brain tissue and pathology Archives of neurology

    Key finding: It is estimated that 2% of the US population lives with long-term disabilities due to a prior TBI, and incidence and prevalence rates are even higher in developing countries. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2012-10-01

    Amyloid deposition, hypometabolism, and longitudinal cognitive decline

    ✓ Peer-reviewed Brain tissue and pathology Annals of neurology

    Key finding: Using data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) population, we examined (1) cross-sectional relationships between amyloid deposition, hypometabolism, and cognition, and (2) associations between amyloid and hypometabolism measurements and longitudinal cognitive measurements. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2012-10-01

    Cerebrospinal fluid proteins predict longitudinal hippocampal degeneration in early-stage dementia of the Alzheimer type

    ✓ Peer-reviewed Tau biomarkers Alzheimer disease and associated disorders

    Key finding: Biomarkers are needed to improve the sensitivity and accuracy of diagnosis, and also prognosis, in individuals with early Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2012-10-01

    Frontotemporal lobar degeneration: epidemiology, pathology, diagnosis and management

    ✓ Peer-reviewed Digital health tools CNS drugs

    Key finding: Additionally, there is a significant clinical, pathological and genetic overlap between FTD and motor neuron disease/amyotrophic lateral sclerosis (FTD-ALS) and the atypical parkinsonian syndromes, progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS). bvFTD is characterized by progressive behavioural impairment and a decline in executive function with frontal lobe-predominant atrophy, SD by a loss of object knowledge with prominent anomia and asymmetrical atrophy of the anterior temporal lobes and PNFA by expressive or motor speech deficits with predominantly left peri-sylvian atrophy.

    Full summary, score breakdown and related studies → Original source

  11. 2012-10-01

    My belief or yours? Differential theory of mind deficits in frontotemporal dementia and Alzheimer's disease

    ✓ Peer-reviewed Disparities Brain : a journal of neurology

    Key finding: It has been suggested that a theory of mind deficit may account for some of the abnormalities in interpersonal behaviour that characterize patients affected by behavioural variant frontotemporal dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2012-10-01

    Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide

    ✓ Peer-reviewed Caregiving The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Here, we found that the level of Aβ oligomers in APOE ε4/ε4 AD patient brains is 2.7 times higher than those in APOE ε3/ε3 AD patient brains, matched for total plaque burden, suggesting that apoE4 impacts the metabolism of Aβ oligomers. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2012-10-01

    Effects of liraglutide on neurodegeneration, blood flow and cognition in Alzheimer´s disease - protocol for a controlled, randomized double-blinded trial

    ✓ Peer-reviewed Treatments Danish medical journal

    Key finding: No registered drug affects the deposition of Aβ in the brain of AD patients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2012-10-01

    Comprehensive search for Alzheimer disease susceptibility loci in the APOE region

    ✓ Peer-reviewed Genetics Archives of neurology

    Key finding: APOE alleles ε2, ε3, and ε4 account for essentially all the inherited risk of AD associated with this region. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2012-10-01

    The genetics of Alzheimer disease

    ✓ Peer-reviewed Genetics Cold Spring Harbor perspectives in medicine

    Key finding: Twin and family studies indicate that genetic factors are estimated to play a role in at least 80% of AD cases.

    Full summary, score breakdown and related studies → Original source

  16. 2012-10-01

    Plasma biomarkers associated with the apolipoprotein E genotype and Alzheimer disease

    ✓ Peer-reviewed Biomarkers Archives of neurology

    Key finding: Plasma biomarker results confirm cerebrospinal fluid studies reporting increased levels of pancreatic polypeptide and N-terminal protein B-type brain natriuretic peptide in patients with AD and mild cognitive impairment. +2 more findings

    Full summary, score breakdown and related studies → Original source

September 2012 9

  1. 2012-09-30

    Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

    ✓ Peer-reviewed Lewy body dementia Nature neuroscience

    Key finding: We found that FUS/TLS binds to RNAs from >5,500 genes in mouse and human brain, primarily through a GUGGU-binding motif.

    Full summary, score breakdown and related studies → Original source

  2. 2012-09-29

    Patients with chronic kidney disease are at an elevated risk of dementia: a population-based cohort study in Taiwan

    ✓ Peer-reviewed Digital health tools BMC nephrology

    Key finding: Patients with CKD could have an elevated dementia risk. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2012-09-29

    Progressive supranuclear palsy presenting as primary lateral sclerosis but lacking parkinsonism, gaze palsy, aphasia, or dementia

    ✓ Peer-reviewed Digital health tools Journal of the neurological sciences

    Key finding: These findings suggest that when tau pathology is prominent in the motor cortex but is minimal in the basal ganglia and brain stem nuclei, a PSP case can lack all classic clinical features of PSP and show only slowly progressive upper motor syndrome, consistent with clinical picture of primary lateral sclerosis.

    Full summary, score breakdown and related studies → Original source

  4. 2012-09-28

    Apolipoprotein E genotype and neurological disease onset in Niemann-Pick disease, type C1

    ✓ Peer-reviewed Genetics American journal of medical genetics. Part A

    Key finding: Niemann-Pick disease, type C1 (NPC1) is a lipid storage disorder that results in progressive neurological impairment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2012-09-28

    Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Previously, we showed that the cysteine protease cathepsin B (CatB) degrades Aβ, most likely by C-terminal truncation, in mice expressing human amyloid precursor protein with familial AD-linked mutations (hAPP(FAD)). +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2012-09-28

    Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice

    ✓ Peer-reviewed Risk genes beyond APOE The American journal of pathology

    Key finding: In APP mice, mutant presenilin 1 (PS1) enhances generation of Aβ42 and inhibits cell survival pathways. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2012-09-28

    Decreased levels of circulating adiponectin in mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Neuromolecular medicine

    Key finding: The aim of the present work was to evaluate adiponectin serum levels in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) as compared to cognitively healthy elders and to correlate these levels with clinical and cognitive parameters. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2012-09-26

    α-Synuclein as CSF and Blood Biomarker of Dementia with Lewy Bodies

    ✓ Peer-reviewed Biomarkers International journal of Alzheimer's disease

    Key finding: Although α-synuclein was initially considered to be an exclusively intracellular protein, it has been found to be secreted into biological fluids. α-Synuclein in biological fluids such as cerebrospinal fluid (CSF) and blood has been discussed as a potential biomarker of DLB and α-synuclein-related disorders, because α-synuclein is characteristically accumulated in the brain of patients with these disorders. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2012-09-26

    Reversion from mild cognitive impairment to normal or near-normal cognition: risk factors and prognosis

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: Even in a cohort of patients seen at dementia research centers, reversion from MCI was fairly common. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →