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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,751–17,775 of 27,380 studies, newest first · page 711 of 1096.

July 2014 23

  1. 2014-07-08

    Plasma proteins predict conversion to dementia from prodromal disease

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: We have identified 10 plasma proteins strongly associated with disease severity and disease progression. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2014-07-07

    Development of a practice guideline for optimal symptom relief for patients with pneumonia and dementia in nursing homes using a Delphi study

    ✓ Peer-reviewed End-of-life care International journal of geriatric psychiatry

    Key finding: We developed a mostly consensus-based practice guideline for patients with dementia and pneumonia and mapped controversial issues for future investigation.

    Full summary, score breakdown and related studies → Original source

  3. 2014-07-04

    How proteomic ApoE serotyping could impact Alzheimer's disease risk assessment: genetic testing by proteomics

    ✓ Peer-reviewed Genetics Expert review of proteomics

    Key finding: Serotyping ApoE using mass spectrometry promises highly accurate results while requiring minimal amounts of blood and reagents, resulting in lower costs, which suggest that proteomic-based ApoE serotyping may eventually become a routine clinical laboratory test.

    Full summary, score breakdown and related studies → Original source

  4. 2014-07-03

    Alzheimer's disease drug-development pipeline: few candidates, frequent failures

    ✓ Peer-reviewed Clinical trials Alzheimer's research & therapy

    Key finding: The Clinicaltrials.gov database demonstrates that relatively few clinical trials are undertaken for AD therapeutics, considering the magnitude of the problem. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2014-07-03

    Association between the Mediterranean diet and cognitive decline in a biracial population

    ✓ Peer-reviewed Prevention trials The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Stronger adherence to the Mediterranean diet may reduce the rate of cognitive decline among black, but not white older adults. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2014-07-03

    Associations between cognitively stimulating leisure activities, cognitive function and age-related cognitive decline

    ✓ Peer-reviewed Prevention trials International journal of geriatric psychiatry

    Key finding: The results also suggest that grammatical reasoning and episodic memory should be targeted in developing appropriate outcome measures to assess efficacy of future interventions, and in developing cognitive training programmes to prevent or delay cognitive decline. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2014-07-02

    Interleukin-6 and C-reactive protein as predictors of cognitive decline in late midlife

    ✓ Peer-reviewed Cognitive tests and assessment Neurology

    Key finding: Peripheral inflammatory markers are elevated in patients with dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2014-07-01

    O4‐11‐06: A RANDOMIZED, DOUBLE‐BLIND, PLACEBO‐CONTROLLED PHASE 2 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF CRENEZUMAB IN PATIENTS WITH MILD TO MODERATE ALZHEIMER'S DISEASE

    ✓ Peer-reviewed Treatments Alzheimer s & Dementia

    Key finding: The co-primary efficacy outcome measures were the changes in the ADAS-Cog12 and CDR-SOB scores from baseline to Week 73. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2014-07-01

    The default mode network is disrupted in Parkinson's disease with visual hallucinations

    ✓ Peer-reviewed Brain scans and imaging Human brain mapping

    Key finding: There were no group differences in cortical thickness but functional coactivation within components of the DMN was significantly lower in both PDVH and PDnonVH groups compared to HC. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2014-07-01

    Validating the 8 CPCSSN case definitions for chronic disease surveillance in a primary care database of electronic health records

    ✓ Peer-reviewed Digital health tools Annals of family medicine

    Key finding: The CPCSSN diagnostic algorithms showed excellent sensitivity and specificity for hypertension, diabetes, epilepsy, and parkinsonism and acceptable values for the other conditions.

    Full summary, score breakdown and related studies → Original source

  11. 2014-07-01

    Alzheimer's disease genetics: from the bench to the clinic

    ✓ Peer-reviewed Genetics Neuron

    Key finding: Several genes have been associated with AD risk for nearly 20 years. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2014-07-01

    Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis

    ✓ Peer-reviewed Biomarkers The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: This resulted in significantly accelerated uptake of exogenously applied Aβ42, with increased localization to and degradation within lysosomes in C17.2 cells and primary astrocytes, indicating that TFEB is sufficient to coordinately enhance uptake, trafficking, and degradation of Aβ. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2014-07-01

    Medial temporal lobe structures and hippocampal subfields in psychotic disorders: findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study

    ✓ Peer-reviewed Hippocampus size on brain scans JAMA psychiatry

    Key finding: Alterations in the hippocampus were evident across psychotic disorders. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2014-07-01

    TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

    ✓ Peer-reviewed Lewy body dementia Science translational medicine

    Key finding: We report that missense mutations associated with FTD and FTD-like syndrome reduce TREM2 maturation, abolish shedding by ADAM proteases, and impair the phagocytic activity of TREM2-expressing cells. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2014-07-01

    mTOR Hyperactivation in down syndrome hippocampus appears early during development

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of neuropathology and experimental neurology

    Key finding: Increased expression of phosphorylated S6, phosphorylated S6 kinase, phosphorylated eukaryotic initiation factor 4E binding protein 1, and phosphorylated mTOR was observed in DS hippocampus compared with controls. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2014-07-01

    Frontotemporal dementia and its subtypes: a genome-wide association study

    ✓ Peer-reviewed How common it is The Lancet. Neurology

    Key finding: Frontotemporal dementia (FTD) is a complex disorder characterised by a broad range of clinical manifestations, differential pathological signatures, and genetic variability. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2014-07-01

    Analysis of burden in caregivers of people with Alzheimer's disease using self-report and supervision hours

    ✓ Peer-reviewed Disparities The journal of nutrition, health & aging

    Key finding: However, interventions that minimize caregiver distress and improve patient functioning may impact on both subjective and objective burden. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2014-07-01

    Resting-state functional MR imaging: a new window to the brain

    ✓ Peer-reviewed Brain scans and imaging Radiology

    Key finding: This suggests that neurologic and psychiatric diseases are characterized by altered interactions between RSNs and therefore the whole brain should be examined as an integral network (with subnetworks), for example, using graph analysis.

    Full summary, score breakdown and related studies → Original source

  19. 2014-07-01

    Multidimensional frailty score for the prediction of postoperative mortality risk

    ✓ Peer-reviewed Getting a diagnosis JAMA surgery

    Key finding: Twenty-five patients (9.1%) died during the follow-up period (median [interquartile range], 13.3 [11.5-16.1] months), including 4 in-hospital deaths after surgery. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2014-07-01

    Diagnostic criteria for vascular cognitive disorders: a VASCOG statement

    ✓ Peer-reviewed Getting a diagnosis Alzheimer disease and associated disorders

    Key finding: The proposed criteria for VCD provide a coherent approach to the diagnosis of this diverse group of disorders, with a view to stimulating clinical and pathologic validation studies.

    Full summary, score breakdown and related studies → Original source

  21. 2014-07-01

    Caregivers' male gender is associated with poor nutrient intake in AD families (NuAD-trial)

    ✓ Peer-reviewed Treatments The journal of nutrition, health & aging

    Key finding: The mean age of caregivers and AD spouses was 75.2 (SD 7.0) and 77.4 years (SD 5.6), respectively.

    Full summary, score breakdown and related studies → Original source

  22. 2014-07-01

    Clinical predictors of severe cerebral amyloid angiopathy and influence of APOE genotype in persons with pathologically verified Alzheimer disease

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: Persons with severe CAA compared with those without CAA were more likely to carry an APOE ε4 allele (64.9% vs 42.8%, respectively; P Conclusions and relevance Being Hispanic and having had a transient ischemic attack-like episode were predictors of CAA in persons with AD.

    Full summary, score breakdown and related studies → Original source

  23. 2014-07-01

    Associations between cerebral small-vessel disease and Alzheimer disease pathology as measured by cerebrospinal fluid biomarkers

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: Microbleed presence was associated with lower CSF Aβ42 in AD and vascular dementia (standardized beta = -0.09, P = .003; standardized beta = -0.30, P = .01), and higher CSF tau in controls (standardized beta = 0.10, P = .03). +3 more findings

    Full summary, score breakdown and related studies → Original source

June 2014 2

  1. 2014-06-29

    GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Nature medicine

    Key finding: In the postmortem brain of individuals with AD, astrocytic GABA and MAOB are significantly upregulated.

    Full summary, score breakdown and related studies → Original source

  2. 2014-06-29

    Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

    ✓ Peer-reviewed Lewy body dementia Nature chemical biology

    Key finding: These findings indicate that the levels and localization of TDP43 critically determine neurotoxicity and show that autophagy induction mitigates neurodegeneration by acting directly on TDP43 clearance.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →