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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,876–17,900 of 27,380 studies, newest first · page 716 of 1096.

May 2014 8

  1. 2014-05-01

    Baseline neuropsychiatric symptoms and the risk of incident mild cognitive impairment: a population-based study

    ✓ Peer-reviewed Clinical safety The American journal of psychiatry

    Key finding: An increased incidence of mild cognitive impairment was observed in community-dwelling elderly adults who had nonpsychotic psychiatric symptoms at baseline. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2014-05-01

    Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

    ✓ Peer-reviewed Disparities Science (New York, N.Y.)

    Key finding: To extend our understanding of the genetic basis of human immune function and dysfunction, we performed an expression quantitative trait locus (eQTL) study of purified CD4(+) T cells and monocytes, representing adaptive and innate immunity, in a multi-ethnic cohort of 461 healthy individuals. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2014-05-01

    The intersection of amyloid beta and tau at synapses in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Neuron

    Key finding: The collapse of neural networks important for memory and cognition, including death of neurons and degeneration of synapses, causes the debilitating dementia associated with Alzheimer's disease (AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2014-05-01

    GSK-3 as potential target for therapeutic intervention in cancer

    ✓ Peer-reviewed Risk factors Oncotarget

    Key finding: In some cases, suppression of GSK-3 activity by phosphorylation by Akt and other kinases has been associated with cancer progression. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2014-05-01

    The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases

    ✓ Peer-reviewed Brain scans and imaging Global advances in health and medicine

    Key finding: Several studies have demonstrated that TUDCA serves as an anti-apoptotic agent for a number of neurodegenerative diseases, including amyotrophic lateral sclerosis, Alzheimer's disease, Parkinson's disease, and Huntington's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2014-05-01

    Therapeutic modulation of Notch signalling--are we there yet?

    ✓ Peer-reviewed Vascular contributions Nature reviews. Drug discovery

    Key finding: The Notch signalling pathway is evolutionarily conserved and is crucial for the development and homeostasis of most tissues. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2014-05-01

    Investigation of TREM2, PLD3, and UNC5C variants in patients with Alzheimer's disease from mainland China

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: To examine whether these variants are genetic risk factors in patients with AD from mainland China, we sequenced exon 2 of TREM2, exon 9 of PLD3, and exon 15 of UNC5C in Chinese Han population including 360 patients with AD and 400 control individuals. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2014-05-01

    A prospective study of chronic obstructive pulmonary disease and the risk for mild cognitive impairment

    ✓ Peer-reviewed Mild cognitive impairment JAMA neurology

    Key finding: A diagnosis of COPD is associated with an increased risk for MCI, particularly NA-MCI. +4 more findings

    Full summary, score breakdown and related studies → Original source

April 2014 17

  1. 2014-04-29

    Role of early life exposure and environment on neurodegeneration: implications on brain disorders

    ✓ Peer-reviewed Risk factors Translational neurodegeneration

    Key finding: Although genetic analysis of these diseases has also been described, yet the mechanisms governing the extent of vulnerability to such diseases remains unresolved. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2014-04-29

    Age-dependent neurovascular dysfunction and damage in a mouse model of cerebral amyloid angiopathy

    ✓ Peer-reviewed Risk genes beyond APOE Stroke

    Key finding: Accumulation of amyloid-β in cerebral blood vessels occurs in familial and sporadic forms of cerebral amyloid angiopathy and is a prominent feature of Alzheimer disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2014-04-27

    ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

    ✓ Peer-reviewed Long-term cohort studies Acta neuropathologica

    Key finding: We report the first genome-wide association study (GWAS) with HS-Aging pathology as an endophenotype. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2014-04-25

    Cognitive reserve and clinical expression of Alzheimer's disease: evidence and implications for brain PET imaging

    ✓ Peer-reviewed Risk factors American journal of nuclear medicine and molecular imaging

    Key finding: Cognitive reserve (CR) refers to the hypothesized capacity of an adult brain to cope with brain damage in order to minimize symptomatology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2014-04-24

    O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond

    ✓ Peer-reviewed Mild cognitive impairment Chemical Society reviews

    Key finding: Despite significant efforts, no therapeutics are available that stop or slow progression of AD, which has driven interest in the basic causes of AD and the search for new therapeutic strategies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2014-04-23

    Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

    ✓ Peer-reviewed Risk genes beyond APOE Frontiers in genetics

    Key finding: We begin with a brief overview of the neuropathological changes seen in the AD brain and an outline of some of the clinical neuropsychological assessments used to measure cognitive deficits associated with the disease.

    Full summary, score breakdown and related studies → Original source

  7. 2014-04-23

    Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans Frontiers in aging neuroscience

    Key finding: These findings suggest that PA may help to preserve hippocampal volume in individuals at increased genetic risk for AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2014-04-22

    The role of apolipoprotein E in neurodegeneration and cardiovascular disease

    ✓ Peer-reviewed Genetics Expert review of proteomics

    Key finding: Research has revealed many other roles for this multifunctional protein. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2014-04-22

    Neuroinflammation in the pathogenesis of Alzheimer's disease. A rational framework for the search of novel therapeutic approaches

    ✓ Peer-reviewed How common it is Frontiers in cellular neuroscience

    Key finding: In the search for new targets to search for novel therapeutic avenues, clinical studies in patients who used anti-inflammatory drugs indicating a lower incidence of AD have been of value to support the neuroinflammatory hypothesis of the neurodegenerative processes and the role of innate immunity in this disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2014-04-19

    Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neurochemistry

    Key finding: BACE1 is a major drug target for Alzheimer's disease because BACE1-mediated cleavage of APP is the first step in the generation of the pathogenic amyloid-β peptides. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2014-04-18

    CSF Aβ42 predicts early-onset dementia in Parkinson disease

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: These in vivo data support the role of Aβ pathology in the etiology and highlight the potential utility of CSF Aβ42 as an early prognostic biomarker of dementia associated with PD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2014-04-18

    Homozygous TREM2 mutation in a family with atypical frontotemporal dementia

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: Recently, homozygous and compound heterozygous TREM2 mutations were identified in rare families with frontotemporal lobar degeneration (FTLD) but without bone involvement. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2014-04-18

    Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease

    ✓ Peer-reviewed Genetics Neurology

    Key finding: High Aβ participants were more likely to be APOE ε4+ than low Aβ participants. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2014-04-16

    Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models

    ✓ Peer-reviewed Brain scans and imaging Stem cell research & therapy

    Key finding: Our data suggest that genetically-modified NSCs could provide a powerful combinatorial approach to not only enhance synaptic plasticity but to also target and modify underlying Alzheimer's disease pathology. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2014-04-15

    The effect of a pre- and postoperative orthogeriatric service on cognitive function in patients with hip fracture: randomized controlled trial (Oslo Orthogeriatric Trial)

    ✓ Peer-reviewed Prevention and risk BMC medicine

    Key finding: Pre- and postoperative orthogeriatric care given in an acute geriatric ward was not effective in reducing delirium or long-term cognitive impairment in patients with hip fracture. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2014-04-14

    Value of serum nonceruloplasmin copper for prediction of mild cognitive impairment conversion to Alzheimer disease

    ✓ Peer-reviewed Genetics Annals of neurology

    Key finding: Among the evaluated parameters, the only significant predictor of conversion to AD was non-Cp copper (hazard ratio = 1.23, 95% confidence interval = 1.03-1.47, p = 0.022); for each additional micromole per liter unit (μmol/l) of non-Cp copper, the hazard increased by ~20%. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2014-04-14

    Sex modifies the APOE-related risk of developing Alzheimer disease

    ✓ Peer-reviewed Genetics Annals of neurology

    Key finding: APOE4 confers greater AD risk in women. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →