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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,001–18,025 of 27,380 studies, newest first · page 721 of 1096.

March 2014 17

  1. 2014-03-01

    Cerium oxide nanoparticle: a remarkably versatile rare earth nanomaterial for biological applications

    ✓ Peer-reviewed Risk factors NPG Asia Materials

    Key finding: Cerium oxide nanoparticles (CeONPs) have attracted much attention because they possess multi-enzyme mimetic properties and have been used in bioanalysis, biomedicine, drug delivery, bioscaffold and so on. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2014-03-01

    Cognition in Late Life Depression: Treatment Considerations

    ✓ Peer-reviewed Risk factors Current treatment options in psychiatry

    Key finding: Late life depression (LLD) frequently presents with cognitive impairment, and growing evidence suggests that these disease processes are "linked" in multiple ways. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2014-03-01

    Beyond comorbidity: expanding the definition and measurement of complexity among older adults using administrative claims data

    ✓ Peer-reviewed Digital health tools Medical care

    Key finding: Claims data studies that include indicators of potentially diminished patient functional status better capture heterogeneity of patients with multiple chronic conditions.

    Full summary, score breakdown and related studies → Original source

  4. 2014-03-01

    Deaths in the United States among persons with Alzheimer's disease (2010-2050)

    ✓ Peer-reviewed End-of-life care Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Individuals with AD comprise a substantial number of older adult deaths in the United States, a number expected to rise considerably in coming decades.

    Full summary, score breakdown and related studies → Original source

  5. 2014-03-01

    Amyloid-ß-directed immunotherapy for Alzheimer's disease

    ✓ Peer-reviewed Treatments Journal of internal medicine

    Key finding: A potential disadvantage is the variability in the antibody response across patients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2014-03-01

    Pathways to Alzheimer's disease

    ✓ Peer-reviewed Treatments Journal of internal medicine

    Key finding: Recent trials of anti-amyloid agents have not produced convincing improvements in clinical outcome in Alzheimer's disease; however, the reason for these poor or inconclusive results remains unclear.

    Full summary, score breakdown and related studies → Original source

  7. 2014-03-01

    Problem-Solving Therapy in the Elderly

    ✓ Peer-reviewed End-of-life care Current treatment options in psychiatry

    Key finding: Our results indicate that PST led to greater reduction in depressive symptoms of late-life major depression than supportive therapy (ST) and reminiscence therapy. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2014-03-01

    Treatment of psychosis and dementia in Parkinson's disease

    ✓ Peer-reviewed Clinical safety Current treatment options in neurology

    Key finding: Psychosis and dementia, in particular, greatly affect quality of life for both patients and caregivers and are associated with poor outcomes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2014-03-01

    Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014

    ✓ Peer-reviewed Brain tissue and pathology Journal of internal medicine

    Key finding: Since then, despite the evaluation of numerous potential treatments in clinical trials, only four cholinesterase inhibitors and memantine have shown sufficient safety and efficacy to allow marketing approval at an international level. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2014-03-01

    Mild cognitive impairment: a concept in evolution

    ✓ Peer-reviewed Mild cognitive impairment Journal of internal medicine

    Key finding: Major controversial issues that remain to be further explored are algorithmic versus clinical classification, reliability of clinical judgment, temporal changes in cognitive performances and predictivity of putative biomarkers.

    Full summary, score breakdown and related studies → Original source

  11. 2014-03-01

    Development and evaluation of a decision aid on mammography screening for women 75 years and older

    ✓ Peer-reviewed Disparities JAMA internal medicine

    Key finding: The median age of participants was 79 years, 69% (31 of 45) were of non-Hispanic white race/ethnicity, and 60% (27 of 45) had attended at least some college. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2014-03-01

    2014 Alzheimer's disease facts and figures

    ✓ Peer-reviewed Caregiving Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: This report discusses the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality rates, costs of care, and overall effect on caregivers and society. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2014-03-01

    Caregiver burden: a clinical review

    ✓ Peer-reviewed Caregiving JAMA

    Key finding: Physicians have a responsibility to recognize caregiver burden. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2014-03-01

    Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Science translational medicine

    Key finding: Clinicopathological evidence suggests that the pathology of Alzheimer's disease (AD) begins many years before the appearance of cognitive symptoms. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2014-03-01

    Advances in the prevention of Alzheimer's disease and dementia

    ✓ Peer-reviewed Prevention and risk Journal of internal medicine

    Key finding: Building infrastructures for international collaborations is necessary for managing the worldwide public health problem of AD and dementia.

    Full summary, score breakdown and related studies → Original source

  16. 2014-03-01

    The A4 study: stopping AD before symptoms begin?

    ✓ Peer-reviewed Prevention and risk Science translational medicine

    Key finding: A new secondary prevention trial in older people with amyloid accumulation at high risk for Alzheimer's disease dementia should provide insights into whether anti-amyloid therapy can delay cognitive decline.

    Full summary, score breakdown and related studies → Original source

  17. 2014-03-01

    Elevated serum pesticide levels and risk for Alzheimer disease

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: Levels of DDE were 3.8-fold higher in the serum of those with AD (mean [SEM], 2.64 [0.35] ng/mg cholesterol) when compared with control participants (mean [SEM], 0.69 [0.1] ng/mg cholesterol; P Conclusions and relevance Elevated serum DDE levels are associated with an increased risk for AD and carriers of an APOE4 ε4 allele may be more susceptible to the effects of DDE. +1 more finding

    Full summary, score breakdown and related studies → Original source

February 2014 8

  1. 2014-02-28

    Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: targets for disease modification?

    ✓ Peer-reviewed Drug development Progress in neurobiology

    Key finding: Growing evidence suggests that dysfunction of these pathways contribute to the progressive loss of neurons in Alzheimer's disease (AD) and Parkinson's disease (PD), the two most frequent neurodegenerative disorders. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2014-02-28

    Logopenic and nonfluent variants of primary progressive aphasia are differentiated by acoustic measures of speech production

    ✓ Peer-reviewed Digital health tools PloS one

    Key finding: Discriminant function analyses revealed that a measure of relative vowel duration differentiated nfvPPA cases from both control and lvPPA cases (r(2) = 0.47) with 88% agreement with expert judgment of presence of apraxia of speech in nfvPPA cases. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2014-02-27

    The ubiquitin-proteasome system in neurodegeneration

    ✓ Peer-reviewed Disease mechanisms Antioxidants & redox signaling

    Key finding: Impairment of the ubiquitin-proteasome system (UPS) has been implicated in the pathogenesis of a wide variety of neurodegenerative disorders, including Alzheimer's, Parkinson's, and Huntington's diseases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2014-02-27

    Lixisenatide rescues spatial memory and synaptic plasticity from amyloid β protein-induced impairments in rats

    ✓ Peer-reviewed Drug development Neuroscience

    Key finding: We found that: (1) bilateral intrahippocampal injection of Aβ25-35 resulted in a significant decline in spatial learning and memory of rats, as well as a suppression of in vivo hippocampal long-term potentiation (LTP); (2) lixisenatide treatment effectively prevented the Aβ25-35-induced impairments; (3) lixisenatide inhibited the Aβ25-35 injection-induced activation of glycogen synthase kinase 3β (GSK3β), with a significant increase in the phosphorylation of ser9 and a significant decrease in the phosphorylation of Y216. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2014-02-27

    Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition

    ✓ Peer-reviewed Hippocampus size on brain scans Alzheimer's research & therapy

    Key finding: Potential mechanisms by which HDAC6 inhibitors might benefit the rTg4510 mouse include stabilization of microtubules secondary to increased tubulin acetylation, increased degradation of tau secondary to increased acetylation of HSP90 or both. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2014-02-26

    A novel presenilin 1 mutation (Ala275Val) as cause of early-onset familial Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers Neuroscience letters

    Key finding: Here, we report on a 50-year-old patient presenting with progressive deterioration of his short-term memory and a family history of early-onset dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2014-02-26

    Subjective cognitive concerns and neuropsychiatric predictors of progression to the early clinical stages of Alzheimer disease

    ✓ Peer-reviewed Mild cognitive impairment The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: From a total sample of 559 older adults from the Massachusetts Alzheimer's Disease Research Center longitudinal cohort, 454 were included in the primary analysis: 283 with clinically normal cognition (CN), 115 with mild cognitive impairment (MCI), and 56 with subjective cognitive concerns (SCC) but no objective impairment, a proposed transitional group between CN and MCI.

    Full summary, score breakdown and related studies → Original source

  8. 2014-02-26

    Neurodegenerative disorder risk in idiopathic REM sleep behavior disorder: study in 174 patients

    ✓ Peer-reviewed Getting a diagnosis PloS one

    Key finding: In a large IRBD cohort diagnosed in a tertiary referal sleep center, prolonged follow-up indicated that the majority of patients are eventually diagnosed with the synucleinopathies PD, DLB and less frequently MSA. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →