Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 14,426–14,450 of 27,380 studies, newest first · page 578 of 1096.
January 2018 25
-
2018-01-01
Association of Long-Term Adherence to the MIND Diet with Cognitive Function and Cognitive Decline in American Women
69/100 ✓ Peer-reviewed Prevention trials The journal of nutrition, health & aging
Key finding: Long-term adherence to the MIND diet was moderately associated with better verbal memory in later life. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2018-01-01
The neuropathology of chronic traumatic encephalopathy
38/100 ✓ Peer-reviewed Disease mechanisms Handbook of clinical neurology
Key finding: Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with repetitive head trauma, including concussion and subconcussion. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2018 no date recorded — placed by publication year
Inflammation as a central mechanism in Alzheimer's disease
54/100 ✓ Peer-reviewed Inflammation and the immune system Alzheimer s & Dementia Translational Research & Clinical Interventions
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized by cognitive decline and the presence of two core pathologies, amyloid β plaques and neurofibrillary tangles.
Full summary, score breakdown and related studies → Original source
-
2018 no date recorded — placed by publication year
Nutritional Status is Associated With Severe Dementia and Mortality
40/100 ✓ Peer-reviewed Risk factors Alzheimer Disease & Associated Disorders
Key finding: Compared with “well-nourished,” “malnourished” PWD had 3-4 times the hazard of severe dementia [hazard ratio (HR), 4.31; P =0.014] and death (HR, 3.04; P <0.001). +2 more findings
Full summary, score breakdown and related studies → Original source
-
2018 no date recorded — placed by publication year
Abstract 9: Alirocumab Prior Authorization Approval and Prescription Fill Rates Among Medicare Advantage Patients in a Large US Managed Care Plan
48/100 ✓ Peer-reviewed Health systems and care delivery Circulation: Cardiovascular Quality and Outcomes
Key finding: A total of 2,098 MAPD patients meeting study inclusion/exclusion criteria and with a PA for alirocumab were identified between March 1, 2016 and February 28, 2017. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
The new paradigm in community-based care: Managing mindset and expectations
31/100 ✓ Peer-reviewed Health systems and care delivery Journal of Emergencies Trauma and Shock
Key finding: Some of the considerations that need to be taken into account in coming to a decision include: Disease prevalence and burden in the country The existing health-care model and system The ratio of health-care providers to patient Cost and health-care funding in the country The current and projected health-care demand and needs The perception of the population on FP s and primary care providers versus that of specialists in hospitals and The networks and strengths of the primary care model in the country. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain
46/100 ✓ Peer-reviewed Inflammation and the immune system EMBO molecular medicine
Key finding: The molecular basis for the overlap of these disorders is not well established. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Probiotic Supplementation in Patients with Alzheimer's Dementia - An Explorative Intervention Study
51/100 ✓ Peer-reviewed Inflammation and the immune system Current Alzheimer research
Key finding: Dysbiosis of intestinal microbiota in the elderly can cause a leaky gut, which may result in silent systemic inflammation and promote neuroinflammation - a relevant pathomechanism in the early course of Alzheimer's disease. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Role of Blood-Brain Barrier in Alzheimer's Disease
46/100 ✓ Peer-reviewed Inflammation and the immune system Journal of Alzheimer's disease : JAD
Key finding: BBB is a highly selective semipermeable structural and chemical barrier which ensures a stable internal environment of the brain and prevents foreign objects invading the brain tissue. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Deep Brain Stimulation of Frontal Lobe Networks to Treat Alzheimer's Disease
47/100 ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD
Key finding: This is a non-randomized phase I prospective open label interventional trial of three subjects with matched comparison groups. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia
62/100 ✓ Peer-reviewed Cognitive tests and assessment JAMA psychiatry
Key finding: Cerebral amyloid-β aggregation is an early event in Alzheimer disease (AD). +3 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
The Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog): Modifications and Responsiveness in Pre-Dementia Populations. A Narrative Review
51/100 ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD
Key finding: Advancements in the research field have shifted focus toward pre-dementia populations, and use of the ADAS-Cog has extended into these pre-dementia studies despite concerns about its ability to detect important changes at these milder stages of disease progression. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Trial of Solanezumab for Mild Dementia Due to Alzheimer's Disease
82/100 ✓ Peer-reviewed Treatments The New England journal of medicine
Key finding: Alzheimer's disease is characterized by amyloid-beta (Aβ) plaques and neurofibrillary tangles. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Hypercapnic and Hypoxic Respiratory Response During Wakefulness and Sleep in a Streptozotocin Model of Alzheimer's Disease in Rats
34/100 ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD
Key finding: These symptoms are aggravated with the progression of the disease. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Bi-directional Association of Cerebrospinal Fluid Immune Markers with Stage of Alzheimer's Disease Pathogenesis
50/100 ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD
Key finding: Yet, studies comparing cerebrospinal fluid (CSF) and plasma immune marker levels of healthy and demented individuals have yielded conflicting results. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Behavioral and transcriptomic analysis of Trem2-null mice: not all knockout mice are created equal
47/100 ✓ Peer-reviewed TREM2 and immune genetics Human molecular genetics
Key finding: Human genetic studies have demonstrated that triggering receptor expressed in myeloid cells 2 (TREM2) coding variants have a strong association with Alzheimer's disease (AD) and other neurodegenerative diseases. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline
54/100 ✓ Peer-reviewed TREM2 and immune genetics Journal of Alzheimer's disease : JAD
Key finding: There are multiple approaches to untangling the genetic architecture of these phenotypes. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Risk of Conversion to Dementia in a Mild Behavioral Impairment Group Compared to a Psychiatric Group and to a Mild Cognitive Impairment Group
49/100 ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD
Key finding: From 348 patients, 126 evolved to dementia (36.2%). +1 more finding
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Estimating Alzheimer's Disease Progression Rates from Normal Cognition Through Mild Cognitive Impairment and Stages of Dementia
62/100 ✓ Peer-reviewed Mild cognitive impairment Current Alzheimer research
Key finding: Transition probabilities from normal cognition through AD severity states are important for understanding patient progression across the AD spectrum.
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer's Disease
50/100 ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD
Key finding: One source of oxidative stress in AD and aMCI brains is that associated with amyloid-β peptide, Aβ1-42 oligomers.
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Repeat expansion diseases
49/100 ✓ Peer-reviewed Lewy body dementia Handbook of clinical neurology
Key finding: I conclude with a brief clinical and genetic description of individual repeat expansion diseases that are most relevant to neurologists.
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Alzheimer-Like Pattern of Hypometabolism Emerges with Elevated Amyloid-β Burden in Down Syndrome
40/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of Alzheimer's disease : JAD
Key finding: In adults with DS, early amyloid-β accumulation in the striatum is divergent from sporadic AD; however, despite the early striatal amyloid-β, glucose hypometabolism was confined to the typical AD-associated regions, which occurs similarly in autosomal dominant AD.
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Advances on Automatic Speech Analysis for Early Detection of Alzheimer Disease: A Non-linear Multi-task Approach
37/100 ✓ Peer-reviewed Digital health tools Current Alzheimer research
Key finding: Finally, the most relevant features are selected by means of the non-parametric Mann- Whitney U-test. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Network pharmacology-based analysis of Chinese herbal Naodesheng formula for application to Alzheimer's disease
37/100 ✓ Peer-reviewed Digital health tools Chinese journal of natural medicines
Key finding: Firstly, we collected the constituents in NDS formula and key targets toward AD. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2018-01-01
Gait in Mild Alzheimer's Disease: Feasibility of Multi-Center Measurement in the Clinic and Home with Body-Worn Sensors: A Pilot Study
50/100 ✓ Peer-reviewed Digital health tools Journal of Alzheimer's disease : JAD
Key finding: Gait is emerging as a potential diagnostic tool for cognitive decline. +1 more finding
Full summary, score breakdown and related studies → Original source
Browse the library by subject, with the full score breakdown →