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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 13,176–13,200 of 27,380 studies, newest first · page 528 of 1096.

February 2019 9

  1. 2019-02-01

    Associations of the Mediterranean diet with cognitive and neuroimaging phenotypes of dementia in healthy older adults

    ✓ Peer-reviewed Disparities The American journal of clinical nutrition

    Key finding: When compared with the Low MedDiet group, the High MedDiet group was associated with better L&M performance and larger dentate gyri. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-02-01

    Psychosocial Pathways to Racial/Ethnic Inequalities in Late-Life Memory Trajectories

    ✓ Peer-reviewed Disparities The journals of gerontology. Series B, Psychological sciences and social sciences

    Key finding: Depression and external locus of control partially mediate racial/ethnic differences in memory trajectories. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2019-02-01

    Visceral obesity relates to deep white matter hyperintensities via inflammation

    ✓ Peer-reviewed Caregiving Annals of neurology

    Key finding: Mediation analyses proposed that visceral obesity contributes to deep white matter lesions through increases in proinflammatory cytokines, suggesting a pathomechanistic link.

    Full summary, score breakdown and related studies → Original source

  4. 2019-02-01

    Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial

    ✓ Peer-reviewed Getting a diagnosis JAMA

    Key finding: Among ambulatory adults with hypertension, treating to a systolic blood pressure goal of less than 120 mm Hg compared with a goal of less than 140 mm Hg did not result in a significant reduction in the risk of probable dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-02-01

    Longitudinal plasma metabolomics of aging and sex

    ✓ Peer-reviewed Prevention and risk Aging

    Key finding: Of 1,097 metabolites tested, 623 (56.8%) were associated with age and 695 (63.4%) with sex after correcting for multiple testing. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2019-02-01

    Late-onset Alzheimer Disease

    ✓ Peer-reviewed Genetics Continuum (Minneapolis, Minn.)

    Key finding: Vascular risk factors, sleep disorders, and traumatic brain injury are associated with an increased risk of AD, while increased cognitive and physical activity throughout the lifespan reduce the risk of disease.

    Full summary, score breakdown and related studies → Original source

  7. 2019-02-01

    Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: Dementia was associated with mortality in 70% of older adults with DS. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2019-02-01

    Early-onset Alzheimer Disease and Its Variants

    ✓ Peer-reviewed Genetics Continuum (Minneapolis, Minn.)

    Key finding: Neuroimaging features of early-onset AD in comparison to late-onset AD include greater frequency of hippocampal sparing and posterior neocortical atrophy, increased tau burden, and greater connectomic changes affecting frontoparietal networks rather than the default mode network. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2019-02 month only

    Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease

    ✓ Peer-reviewed Laboratory science Nature Medicine

    Key finding: 405 people (243 mutation carriers, 162 non-carrier controls) from the DIAN study had serum NfL measured +3 more findings

    Full summary, score breakdown and related studies → Original source

January 2019 16

  1. 2019-01-31

    Atrial Fibrillation and Risk of Dementia: Epidemiology, Mechanisms, and Effect of Anticoagulation

    ✓ Peer-reviewed Risk factors Frontiers in neuroscience

    Key finding: Several longitudinal studies have reported an association between AF and dementia independently of stroke history. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-01-31

    Synergistic Effect of Amyloid-β and Tau Disrupts Neural Circuits

    ✓ Peer-reviewed Drug development ACS chemical neuroscience

    Key finding: Although studies have shown that the interaction between Aβ and tau causes enhanced AD pathology; there is a lack of precise understanding of the functional consequences for integrated neural circuits. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2019-01-31

    Mutation profile of APP, PSEN1, and PSEN2 in Chinese familial Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE Neurobiology of aging

    Key finding: For the sake of characterizing mutations, index patients from 148 families with FAD were enrolled from mainland China. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2019-01-31

    18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes

    ✓ Peer-reviewed Disease mechanisms Alzheimer's research & therapy

    Key finding: All patients underwent MRI and β-amyloid biomarker testing via 11 C-PiB or cerebrospinal fluid. 18 F-flortaucipir uptake in patients was compared to 53 β-amyloid negative normal controls using voxelwise and pre-specified region of interest approaches. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-01-31

    Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Translational psychiatry

    Key finding: Rare coding variants in TREM2, PLCG2, and ABI3 were recently associated with the susceptibility to Alzheimer's disease (AD) in Caucasians. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2019-01-31

    The temporal trend and distribution characteristics in mortality of Alzheimer's disease and other forms of dementia in China: Based on the National Mortality Surveillance System (NMS) from 2009 to 2015

    ✓ Peer-reviewed Risk factors PLoS ONE

    Key finding: In China, the crude mortality from AD and other forms of dementia increased from 2009 to 2015, but the age-standardized mortality decreased. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2019-01-31

    Inferior and medial temporal tau and cortical amyloid are associated with daily functional impairment in Alzheimer's disease

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's research & therapy

    Key finding: A decline in instrumental activities of daily living (IADL) correlates with the progression from mild cognitive impairment (MCI) to Alzheimer's disease (AD) dementia and has been associated with frontal and parietal hypometabolism, lower cerebrospinal fluid amyloid β 1-42 , and inferior temporal cortical thinning. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2019-01-30

    Recent advances in the genetics of frontotemporal dementia

    ✓ Peer-reviewed TREM2 and immune genetics Current genetic medicine reports

    Key finding: In this review we highlight recent advances in the human genetics of frontotemporal dementia (FTD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2019-01-30

    Analysis of the relationship between the gut microbiome and dementia: a cross-sectional study conducted in Japan

    ✓ Peer-reviewed Prevention and risk Scientific reports

    Key finding: Dysregulation of the gut microbiome is associated with several life-threatening conditions and thus might represent a useful target for the prevention of dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2019-01-30

    Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease

    ✓ Peer-reviewed Biomarkers The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Double-mutant 5xF:pGB mice displayed improvements in cognitive tasks compared with 5xFAD littermates. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2019-01-29

    Genetic screening in early-onset Alzheimer's disease identified three novel presenilin mutations

    ✓ Peer-reviewed Risk genes beyond APOE Neurobiology of aging

    Key finding: Our findings extend the mutation spectrum of EOAD and underline the clinical heterogeneity among PSEN1 and PSEN2 mutation carriers.

    Full summary, score breakdown and related studies → Original source

  12. 2019-01-29

    A Biophysical Approach to the Identification of Novel ApoE Chemical Probes

    ✓ Peer-reviewed Genetics Biomolecules

    Key finding: The hypothesis that a structural difference between ApoE4 and ApoE3 (and ApoE2) is the cause of the ApoE4-associated increased risk for AD forms the basis of a therapeutic approach to modulate ApoE4 structure, and we were therefore interested in screening to identify new chemical probes for ApoE4.

    Full summary, score breakdown and related studies → Original source

  13. 2019-01-29

    Claudin-5: gatekeeper of neurological function

    ✓ Peer-reviewed Risk factors Fluids and barriers of the CNS

    Key finding: Simultaneously, this protective barrier hinders the therapeutic effectiveness of central nervous system acting drugs with over 95% of small molecule therapeutics unable to bypass the blood-brain barrier. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-01-29

    Chitosan oligosaccharide (COS): An overview

    ✓ Peer-reviewed Drug development International journal of biological macromolecules

    Key finding: Innumerable studies have revealed in the recent decade that COS has various promising biomedical implications in the past analysis, current developments and potential applications in a biomedical, pharmaceutical and agricultural sector. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-01-28

    PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model

    ✓ Peer-reviewed Disease mechanisms Nature communications

    Key finding: Single cell RNA-seq revealed that the homing macrophages expressed unique scavenger molecules including macrophage scavenger receptor 1 (MSR1), which was shown here to be required for the effect of PD-L1 blockade in disease modification. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2019-01-28

    Chronic Obstructive Pulmonary Disease and Risk of Dementia and Mortality in Lower to Middle Income Countries

    ✓ Peer-reviewed Risk factors Journal of Alzheimer s Disease

    Key finding: Over the 3-year follow-up, almost 10% of participants developed dementia and 14% were deceased. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →