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49/100

✓ Peer-reviewed alzhub usefulness score 49 out of 100. Mild cognitive impairment

Topic: Risk, prevention and care in population studies

Background There is insufficient available information on behavioral changes in the absence of cognitive impairment as factors increasing the risk of conversion to dementia. Objective To observe and analyze patients with mild behavioral impairment (MBI), mild cognitive impairment (MCI), and a psychiatry group (PG) to compare the risk of progression to dementia. Methods From 677 initially assessed ≥60-year-old patients, a series of 348 patients was studied for a five-year period until censoring or conversion to dementia: 96 with MBI, 87 with MCI, and 165 with general psychiatry disorders, including 4 subgroups: Anxiety, Depression, Psychosis and Others. All patients were assessed with clinical, psychiatric, neurological, neuropsychological, and neuroimaging studies. Results From 348 patients, 126 evolved to dementia (36.2%). Conversion was significantly higher in MBI (71.5%), followed by the MCI-MBI overlap (59.6%) and MCI (37.8%) groups, compared to PG (13.9%) (Log-rank p Conclusion Conversion to dementia is significantly higher in patients with neuropsychiatric symptoms. The MBI concept generates a new milestone in the refining of diagnosis of neurodegenerative diseases and the possibility of creating neuropsychiatric profiles. Its earlier identification will allow new possibilities for therapeutic intervention.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Taragano, F. E., Allegri, R. F., Heisecke, S. L., Martelli, M. I., Feldman, M. L., Sánchez, V., et al. (2018). Risk of Conversion to Dementia in a Mild Behavioral Impairment Group Compared to a Psychiatric Group and to a Mild Cognitive Impairment Group. Journal of Alzheimer's disease : JAD. https://doi.org/10.3233/jad-170632

Vancouver

Taragano FE, Allegri RF, Heisecke SL, Martelli MI, Feldman ML, Sánchez V, et al. Risk of Conversion to Dementia in a Mild Behavioral Impairment Group Compared to a Psychiatric Group and to a Mild Cognitive Impairment Group. Journal of Alzheimer's disease : JAD. 2018. doi:10.3233/jad-170632. PMID: 29439333.

BibTeX

@article{taragano2018-29439333,
  author  = {Taragano, F. E. and Allegri, R. F. and Heisecke, S. L. and Martelli, M. I. and Feldman, M. L. and Sánchez, V. and García, V. A. and Tufro, G. and others},
  title   = {{Risk of Conversion to Dementia in a Mild Behavioral Impairment Group Compared to a Psychiatric Group and to a Mild Cognitive Impairment Group}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2018},
  doi     = {10.3233/jad-170632},
  pmid    = {29439333},
  url     = {https://doi.org/10.3233/jad-170632}
}

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Key findings

Results From 348 patients, 126 evolved to dementia (36.2%).
Conversion was significantly higher in MBI (71.5%), followed by the MCI-MBI overlap (59.6%) and MCI (37.8%) groups, compared to PG (13.9%) (Log-rank p Conclusion Conversion to dementia is significantly higher in patients with neuropsychiatric symptoms.

Why it matters

This study followed patients with mild behavioral impairment, mild cognitive impairment, and psychiatric disorders for five years to compare conversion to dementia. Conversion was significantly higher in the mild behavioral impairment group, suggesting that earlier identification of neuropsychiatric symptoms could allow new possibilities for therapeutic intervention.

Study details

Participants348
Effect size36.2%; 71.5%; 59.6%
Evidence strengthLow

How this study scored 49/100

Published in a peer-reviewed journal. Scored zero for study design and randomized / blinded because the record does not state it.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Journal of Alzheimer's disease : JAD)
Journal's citation record	2 / 4	Journal of Alzheimer s Disease: journal h-index 218 (OpenAlex, 2026-10-29)
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	2 / 5	2018 — within 10 year(s) of the newest study here
Sample size	2 / 4	348 participants
Effect reported	2 / 3	Effect reported as a number, without an interval or test
Studied in people	3 / 3	Studied in people (participant count stated)
Randomized / blinded	0 / 2	No randomization or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	5 / 7	Cited 143 times (OpenAlex, 2026-10-10)
Citations per year	3 / 5	14.3 citations a year over 10 year(s) since 2018
Impact for its field and year	4 / 6	Cited 11.0× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	2 / 6	Cited by 9 other studies in this library
Still being cited	2 / 4	Cited 42 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	1 / 4	Last-listed author Carol Dillon: h-index 13 (OpenAlex, whole career)
Institution's track record	0 / 3	Consejo Nacional de Investigaciones Científicas y Técnicas: institution h-index 639 (OpenAlex)
Multicenter collaboration	1 / 3	OpenAlex lists 2 institution(s) in 1 country
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 29439333)
Free to read	0 / 2	Behind a paywall — scores zero
Total	49 / 100	—

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