alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 14,451–14,475 of 27,380 studies, newest first · page 579 of 1096.

January 2018 23

  1. 2018-01-01

    Asymmetry of post-mortem neuropathology in behavioural-variant frontotemporal dementia

    ✓ Peer-reviewed Digital health tools Brain : a journal of neurology

    Key finding: Antemortem behavioural and anatomic abnormalities have largely been associated with right hemisphere disease in behavioural-variant frontotemporal dementia, but post-mortem neuropathological examination of bilateral hemispheres remains to be defined. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2018-01-01

    Use of Speech Analyses within a Mobile Application for the Assessment of Cognitive Impairment in Elderly People

    ✓ Peer-reviewed Digital health tools Current Alzheimer research

    Key finding: Our results indicate the potential value of vocal analytics and the use of a mobile application for accurate automatic differentiation between SCI, MCI and AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2018-01-01

    Differences Between Women and Men in Incidence Rates of Dementia and Alzheimer's Disease

    ✓ Peer-reviewed How common it is Journal of Alzheimer's disease : JAD

    Key finding: This pattern is consistent with women's survival to older ages compared to men. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2018-01-01

    Religious Orders Study and Rush Memory and Aging Project

    ✓ Peer-reviewed How common it is Journal of Alzheimer's disease : JAD

    Key finding: Complexity at multiple levels needs to be understood and overcome to develop effective treatments and preventions for cognitive decline and AD dementia.

    Full summary, score breakdown and related studies → Original source

  5. 2018-01-01

    Body Mass Index and Decline in Cognitive Function in Older Black and White Persons

    ✓ Peer-reviewed Disparities The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Late-life lower BMI relates to faster rates of decline in cognition, specifically semantic memory and episodic memory, in both blacks and whites. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2018-01-01

    G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo

    ✓ Peer-reviewed Caregiving EMBO molecular medicine

    Key finding: We performed a screen that identified three structurally related small molecules that specifically stabilise GGGGCC repeat G-quadruplex RNA We investigated their effect in C9orf72 patient iPSC-derived motor and cortical neurons and show that they significantly reduce RNA foci burden and the levels of dipeptide repeat proteins. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2018-01-01

    Neuropathologic Correlates of Psychiatric Symptoms in Alzheimer's Disease

    ✓ Peer-reviewed Caregiving Journal of Alzheimer's disease : JAD

    Key finding: In Braak I/II, significantly increased odds were detected for agitation, anxiety, appetite changes, depression, and sleep disturbances, compared to controls. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2018-01-01

    Dementia After Moderate-Severe Traumatic Brain Injury: Coexistence of Multiple Proteinopathies

    ✓ Peer-reviewed Brain scans and imaging Journal of neuropathology and experimental neurology

    Key finding: Neuropathological evaluation revealed abundant β-amyloid neuritic and cored plaques, diffuse β-amyloid plaques, and frequent hyperphosphorylated-tau neurofibrillary tangles (NFT) involving much of the cortex, including insula and mammillary bodies in both cases. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2018-01-01

    The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases

    ✓ Peer-reviewed Brain scans and imaging Journal of neuropathology and experimental neurology

    Key finding: Converging data indicate that the amygdala may represent a preferential locus for a pivotal transition from a relatively benign clinical condition to a more aggressive disease wherein multiple protein species are misfolded. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2018-01-01

    Widespread brain tau and its association with ageing, Braak stage and Alzheimer's dementia

    ✓ Peer-reviewed Getting a diagnosis Brain : a journal of neurology

    Key finding: In older cognitively unimpaired individuals (≥50 years), widespread, age-related elevated tau signal was seen among those with normal or abnormal amyloid status as compared to younger cognitively unimpaired individuals (30-49 years). +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2018-01-01

    Amsterdam Dementia Cohort: Performing Research to Optimize Care

    ✓ Peer-reviewed Getting a diagnosis Journal of Alzheimer's disease : JAD

    Key finding: In this cohort profile, we provide an overview of the results produced based on the Amsterdam Dementia Cohort. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2018-01-01

    The Vascular Hypothesis of Alzheimer's Disease: A Key to Preclinical Prediction of Dementia Using Neuroimaging

    ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD

    Key finding: There is currently an international research drive from neuroimaging groups to seek new perspectives that can broaden our understanding of AD and improve lifestyle. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2018-01-01

    Metformin Use Associated with Reduced Risk of Dementia in Patients with Diabetes: A Systematic Review and Meta-Analysis

    ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD

    Key finding: Metformin should continue to be used as a first line therapy for diabetes in patients at risk of developing dementia or Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2018-01-01

    Homocysteine and Dementia: An International Consensus Statement

    ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD

    Key finding: We here present a Consensus Statement, based on the Bradford Hill criteria, and conclude that elevated plasma total homocysteine is a modifiable risk factor for development of cognitive decline, dementia, and Alzheimer's disease in older persons.

    Full summary, score breakdown and related studies → Original source

  15. 2018-01-01

    Different Cognitive Frailty Models and Health- and Cognitive-related Outcomes in Older Age: From Epidemiology to Prevention

    ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD

    Key finding: Frailty, a critical intermediate status of the aging process that is at increased risk for negative health-related events, includes physical, cognitive, and psychosocial domains or phenotypes. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2018-01-01

    The Association between Social Engagement, Loneliness, and Risk of Dementia: A Systematic Review and Meta-Analysis

    ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD

    Key finding: It has been reported that social engagement may be associated with dementia risk. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2018-01-01

    Efficacy of Transcranial Direct Current Stimulation Combined with Cognitive Training in the Treatment of Apathy in Patients with Alzheimer's Disease: Study Protocol for a Randomized Trial

    ✓ Peer-reviewed Treatments Reviews on recent clinical trials

    Key finding: This article primarily describes the design of a monocentre, randomized, doubleblind trial to be conducted in France to evaluate the effect of the combination of tDCS and cognitive training on apathy compared to a group treated exclusively by cognitive training (sham tDCS). +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2018-01-01

    Trajectory of the MAPT-PACC-Preclinical Alzheimer Cognitive Composite in the Placebo Group of a Randomized Control Trial: Results from the MAPT Study: Lessons for Further Trials

    ✓ Peer-reviewed Treatments The journal of prevention of Alzheimer's disease

    Key finding: Our findings as expected showed subjects with older age (>75), higher beta amyloid brain deposition, APOE-ε4 allele carriers, with low RBC DHA+EPA levels and higher CDR level are at higher risk of cognitive decline.

    Full summary, score breakdown and related studies → Original source

  19. 2018-01-01

    Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (the ADvance Trial): A Two Year Follow-up Including Results of Delayed Activation

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: Additional study of mechanisms of action and methods for titrating stimulation parameters will be needed to determine if DBS has potential as an AD treatment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2018-01-01

    Effect of Idalopirdine as Adjunct to Cholinesterase Inhibitors on Change in Cognition in Patients With Alzheimer Disease: Three Randomized Clinical Trials

    ✓ Peer-reviewed Treatments JAMA

    Key finding: Dose group efficacy required a significant benefit over placebo for the primary end point and 1 or more key secondary end points. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2018-01-01

    The genetic landscape of Alzheimer disease

    ✓ Peer-reviewed Genetics Handbook of clinical neurology

    Key finding: This area of research has come a long way with many and important results allowing a better understanding of the disease.

    Full summary, score breakdown and related studies → Original source

  22. 2018-01-01

    Cognitive Aging in Black and White Americans: Cognition, Cognitive Decline, and Incidence of Alzheimer Disease Dementia

    ✓ Peer-reviewed Genetics Epidemiology (Cambridge, Mass.)

    Key finding: The higher risk of AD among blacks may stem from lower level of cognitive test performance persisting throughout the observation period rather than faster rate of late-life cognitive decline. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2018-01-01

    Comprehension of an Elevated Amyloid Positron Emission Tomography Biomarker Result by Cognitively Normal Older Adults

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: The Study of Knowledge and Reactions to Amyloid Testing, a substudy of an AD prevention trial, involved 2 semistructured telephone interviews with 80 participants recruited from 9 study sites: 50 received elevated and 30 received not elevated amyloid PET scan results. +4 more findings

    Full summary, score breakdown and related studies → Original source

December 2017 2

  1. 2017-12-30

    Polygenic risk for Alzheimer's disease influences precuneal volume in two independent general populations

    ✓ Peer-reviewed Genetics Neurobiology of aging

    Key finding: Based on previous results from large-scale genome-wide association studies, recent studies found an association between the polygenic risk score (PGRS) of AD and the structure of some preselected brain regions, but the effects of AD PGRS on all voxels of the brain have not been fully investigated. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2017-12-29

    Acupuncture for patients with mild to moderate Alzheimer's disease: a randomized controlled trial

    ✓ Peer-reviewed Cognitive tests and assessment BMC complementary and alternative medicine

    Key finding: Alzheimer's disease (AD) is the most common cause of dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →