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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 20,676–20,700 of 27,380 studies, newest first · page 828 of 1096.

July 2010 25

  1. 2010-07-28

    REM sleep behavior disorder preceding other aspects of synucleinopathies by up to half a century

    ✓ Peer-reviewed Risk factors Neurology

    Key finding: These cases illustrate that the alpha-synuclein pathogenic process may start decades before the first symptoms of PD, DLB, or MSA.

  2. 2010-07-27

    The hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research?

    ✓ Peer-reviewed Risk factors Molecular psychiatry

    Key finding: Major depressive disorder (MDD) has until recently been conceptualized as an episodic disorder associated with 'chemical imbalances' but no permanent brain changes. +4 more findings

  3. 2010-07-27

    Advance directives for euthanasia in dementia: do law-based opportunities lead to more euthanasia?

    ✓ Peer-reviewed End-of-life care Health policy (Amsterdam, Netherlands)

    Key finding: Over the years 2005-2006, many ECPs took care of patients with dementia and an ADE, actual life termination of these patients took place very rarely and never in incompetent patients. +4 more findings

  4. 2010-07-27

    A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor

    ✓ Peer-reviewed Risk factors Neuroscience letters

    Key finding: Seven weeks of HFD significantly decreased the numbers of newly generated cells in the dentate gyrus of the hippocampus without neuronal loss. +1 more finding

  5. 2010-07-26

    Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Based on the results of a genome-wide screen, we show that reactive oxygen species (ROS) serve as common mediators upstream of the activation of the type III PI3 kinase, which is critical for the initiation of autophagy. +1 more finding

  6. 2010-07-26
  7. 2010-07-23

    Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression

    ✓ Peer-reviewed Mild cognitive impairment Biological psychiatry

    Key finding: These data support the hypothesis that neuronal endosomal dysfunction is associated with preclinical AD. +3 more findings

  8. 2010-07-19
  9. 2010-07-19

    Targeting and managing behavioral symptoms in individuals with dementia: a randomized trial of a nonpharmacological intervention

    ✓ Peer-reviewed Caregiving Journal of the American Geriatrics Society

    Key finding: At 16 weeks, 67.5% of intervention caregivers reported improvement in targeted problem behavior, compared with 45.8% of caregivers in a no-treatment control group (P=.002), and reduced upset with (P=.03) and enhanced confidence managing (P=.01) the behavior.

  10. 2010-07-17

    AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation

    ✓ Peer-reviewed Disease mechanisms Neurobiology of aging

    Key finding: Hyperglycemia enhances the formation of advanced glycation end products (AGEs) that result from the auto-oxidation of glucose and fructose. +2 more findings

  11. 2010-07-14

    In situ monitoring of health in older adults: technologies and issues

    ✓ Peer-reviewed Clinical safety Journal of the American Geriatrics Society

    Key finding: This article identifies and discusses the important issues regarding the use of monitoring technologies in elderly patients. +4 more findings

  12. 2010-07-12

    Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics ASN neuro

    Key finding: In the present study we examined, in a transgenic model of amyloid pathology, the expression of two molecules previously implicated in decreasing the severity of autoimmune responses: TREM2 (triggering receptor expressed on myeloid cells 2) and the intracellular tolerance-associated transcript, Tmem176b (transmembrane domain protein 176b). +3 more findings

  13. 2010-07-08

    Sex differences in the association of the apolipoprotein E epsilon 4 allele with incidence of dementia, cognitive impairment, and decline

    ✓ Peer-reviewed Disparities Neurobiology of aging

    Key finding: ApoE4(+) predicted dementia significantly (hazard ratio [HR] = 2.89; 95% confidence interval [CI], 1.93-4.33), with nonsignificant sex differences. +2 more findings

  14. 2010-07-06

    Risk for Fractures with Centrally Acting Muscle Relaxants: An Analysis of a National Medicare Advantage Claims Database

    ✓ Peer-reviewed Health systems and care delivery Annals of Pharmacotherapy

    Key finding: After adjusting demographic and clinical covariates, muscle relaxants, long-acting benzodiazepines, and short-acting benzodiazepines were associated with a high risk of fracture injuries, with odds ratios of 1.40 (95% CI 1.15 to 1.72; p < 0.001), 1.9 (95% CI 1.49 to 2.43; p < 0.001), and 1.33 (95% CI 1.15 to 1.55; p < 0.001), respectively. +3 more findings

  15. 2010-07-06

    ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

    ✓ Peer-reviewed Lewy body dementia The EMBO journal

    Key finding: The majority of fALS-associated mutations occur within the NLS and impair nuclear import to a degree that correlates with the age of disease onset. +4 more findings

  16. 2010-07-06

    Assessment of dementia in ethnic minority patients in Europe: a European Alzheimer's Disease Consortium survey

    ✓ Peer-reviewed Disparities International psychogeriatrics

    Key finding: Ethnic minority patients are seen on a regular basis in European dementia clinics. +1 more finding

  17. 2010-07 month only

    Bapineuzumab

    ✓ Peer-reviewed Clinical trials Expert opinion on biological therapy

    Key finding: OF THE FIELD: Alzheimer's disease is the leading cause of dementia in the elderly, and there is no disease-modifying therapy yet available.

  18. 2010-07-01

    CSF-tau and CSF-Abeta(1-42) in posterior cortical atrophy

    ✓ Peer-reviewed Tau biomarkers Dementia and geriatric cognitive disorders

    Key finding: The Abeta(1-42), T-tau and P-tau(181) levels in PCA patients differed significantly (p < 0.02) from those in healthy controls but were indistinguishable from subjects with a clinical diagnosis of AD. +2 more findings

  19. 2010-07-01

    An examination of Alzheimer's disease case definitions using Medicare claims and survey data

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Different information sources yield widely varied prevalence and expenditure estimates.

  20. 2010-07-01

    Survival and comfort after treatment of pneumonia in advanced dementia

    ✓ Peer-reviewed End-of-life care Archives of internal medicine

    Key finding: Antimicrobial treatment of suspected pneumonia episodes is associated with prolonged survival but not with improved comfort in nursing home residents with advanced dementia. +3 more findings

  21. 2010-07-01

    Rapid appraisal of barriers to the diagnosis and management of patients with dementia in primary care: a systematic review

    ✓ Peer-reviewed Caregiving BMC family practice

    Key finding: Much can still be done in the way of service development and provision, GP training and education, and the eradication of stigma attached to dementia, to improve the early detection and management of dementia. +1 more finding

  22. 2010-07-01

    Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

    ✓ Peer-reviewed Disease mechanisms Nature neuroscience

    Key finding: Diverse lines of evidence suggest that amyloid-beta (Abeta) peptides have a causal role in its pathogenesis, but the underlying mechanisms remain uncertain.

  23. 2010-07-01

    Does corticobasal degeneration exist? A clinicopathological re-evaluation

    ✓ Peer-reviewed Risk factors Brain : a journal of neurology

    Key finding: The pathological findings of corticobasal degeneration are associated with several distinct clinical syndromes, and the corticobasal syndrome has been linked with a number of diverse pathologies. +1 more finding

  24. 2010-07-01

    Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons

    ✓ Peer-reviewed Treatments The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Live imaging of fluorescent protein-tagged organelles revealed a marked decrease in axonal trafficking of dense-core vesicles and mitochondria in the presence of 0.5 microm AbetaOs. +2 more findings

  25. 2010-07-01

    The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE

    ✓ Peer-reviewed Genetics Neurobiology of aging

    Key finding: The genetic component of this late onset form of AD has been the target of a large number of studies, because only one genetic risk factor (APOE4) has been consistently associated with the disease. +1 more finding

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