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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 16,926–16,950 of 27,380 studies, newest first · page 678 of 1096.

June 2015 7

  1. 2015-06-01

    Cerebrospinal Fluid Markers of Neurodegeneration and Rates of Brain Atrophy in Early Alzheimer Disease

    ✓ Peer-reviewed Tau biomarkers JAMA neurology

    Key finding: Measures of neuronal loss are likely good surrogates for clinical and radiological disease progression in Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2015-06-01

    Effect of Cognitive Reserve on Age-Related Changes in Cerebrospinal Fluid Biomarkers of Alzheimer Disease

    ✓ Peer-reviewed Tau biomarkers JAMA neurology

    Key finding: Although advancing age is the strongest risk factor for the development of symptomatic Alzheimer disease (AD), recent studies have shown that there are individual differences in susceptibility to age-related alterations in the biomarkers of AD pathophysiology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2015-06-01

    THE QUICK DEMENTIA RATING SYSTEM (QDRS): A RAPID DEMENTIA STAGING TOOL

    ✓ Peer-reviewed Caregiving Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: The QDRS provides a rapid method to determine study eligibility; stage patients in clinical practice; and improve case ascertainment in population studies. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2015-06-01

    Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective

    ✓ Peer-reviewed Prevention and risk Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The Association believes there is sufficient evidence to support the link between several modifiable risk factors and a reduced risk for cognitive decline, and sufficient evidence to suggest that some modifiable risk factors may be associated with reduced risk of dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2015-06-01

    Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease

    ✓ Peer-reviewed Genetics Environmental research

    Key finding: Exposure to fossil-fuel combustion sources increases the risk for obesity and diabetes, while long-term exposure to fine particulate matter (PM2.5) and ozone (O3) above US EPA standards is associated with increased risk of Alzheimer's disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2015-06-01

    APOEε2 is associated with milder clinical and pathological Alzheimer disease

    ✓ Peer-reviewed Genetics Annals of neurology

    Key finding: Even when adjusted for age at onset, symptom duration, and other demographic variables, APOEε2 is associated with milder AD pathology and less severe antemortem cognitive impairment compared to APOEε3 and ε4 alleles, suggesting a relative neuroprotective effect of APOEε2 in AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2015-06 month only

    Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

    ✓ Peer-reviewed Laboratory science Nature Neuroscience

    Key finding: Autosomal-dominant Alzheimer's mutations that overproduce amyloid-beta cause the disease, while mutations that solely overproduce tau do not, supporting amyloid as an upstream trigger +3 more findings

    Full summary, score breakdown and related studies → Original source

May 2015 18

  1. 2015-05-28

    Gout and the risk of dementia: a nationwide population-based cohort study

    ✓ Peer-reviewed Digital health tools Arthritis research & therapy

    Key finding: Patients with gout have a lower risk of developing dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2015-05-28

    The effect of cognitive-motor dual-task training on cognitive function and plasma amyloid β peptide 42/40 ratio in healthy elderly persons: a randomized controlled trial

    ✓ Peer-reviewed Biomarkers BMC geriatrics

    Key finding: Cognitive-motor dual-task training was more beneficial than single-task training alone in improving broader domains of cognitive functions of elderly persons, and the improvement was not directly due to modulating Aβ metabolism. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2015-05-28

    Deficits in narrative discourse elicited by visual stimuli are already present in patients with mild cognitive impairment

    ✓ Peer-reviewed Digital health tools Frontiers in aging neuroscience

    Key finding: According to our findings, patients with a-MCI already present narrative deficits that are characterized by mild discursive difficulties that are less severe than those found in patients with AD.

    Full summary, score breakdown and related studies → Original source

  4. 2015-05-27

    Prion-Protein-interacting Amyloid-β Oligomers of High Molecular Weight Are Tightly Correlated with Memory Impairment in Multiple Alzheimer Mouse Models

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: However, the multivalent and unstable nature of Aβo limits molecular characterization and hinders research reproducibility. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2015-05-27

    Classification and clinicoradiologic features of primary progressive aphasia (PPA) and apraxia of speech

    ✓ Peer-reviewed Digital health tools Cortex; a journal devoted to the study of the nervous system and behavior

    Key finding: Blinded diagnoses were made using operational definitions with important differences compared to the consensus criteria. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2015-05-27

    Electroacupuncture for older adults with mild cognitive impairment: study protocol for a randomized controlled trial

    ✓ Peer-reviewed Treatments Trials

    Key finding: The study will provide evidence for evaluating and understanding the role of electroacupuncture in the treatment of Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2015-05-24

    A randomised controlled trial investigating the effects of Mediterranean diet and aerobic exercise on cognition in cognitively healthy older people living independently within aged care facilities: the Lifestyle Intervention in Independent Living Aged Care (LIILAC) study protocol [ACTRN12614001133628]

    ✓ Peer-reviewed Prevention trials Nutrition journal

    Key finding: It is hypothesised that exercise and Mediterranean diet interventions, both individually and in combination, will result in improvements in cognitive performance compared with controls. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2015-05-23

    Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging

    ✓ Peer-reviewed Digital health tools Acta neuropathologica communications

    Key finding: We conclude that variations in morphologies among microglial cells, and cells of macrophage lineage, can help guide future work connecting neuroinflammatory mechanisms with specific neurodegenerative disease subtypes. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2015-05-22

    Adverse drug reactions in special populations - the elderly

    ✓ Peer-reviewed Clinical safety British journal of clinical pharmacology

    Key finding: The majority of ADRs in older people are Type A, potentially avoidable and associated with commonly prescribed medications. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2015-05-22

    Neighbourhood racial/ethnic composition and segregation and trajectories of cognitive decline among US older adults

    ✓ Peer-reviewed Risk factors Journal of Epidemiology & Community Health

    Key finding: In models adjusting for individual demographic and health characteristics, Hispanic composition had a significant positive association with cognitive function (standardised β=0.136, p<0.05) and moderate evidence of an association with greater cognitive decline (standardised β=-0.014, p=0.09). +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2015-05-22

    Risk factors for predicting progression from mild cognitive impairment to Alzheimer's disease: a systematic review and meta-analysis of cohort studies

    ✓ Peer-reviewed Mild cognitive impairment Journal of neurology, neurosurgery, and psychiatry

    Key finding: Patients with MCI with APOEε4, abnormal CSF τ level, hippocampal and medial temporal lobe atrophy, entorhinal atrophy, depression, diabetes, hypertension, older age, female gender, lower MMSE score and higher ADAS-cog score, had a high risk for the progression to AD.

    Full summary, score breakdown and related studies → Original source

  12. 2015-05-21

    The relative importance of imaging markers for the prediction of Alzheimer's disease dementia in mild cognitive impairment - Beyond classical regression

    ✓ Peer-reviewed Long-term cohort studies NeuroImage. Clinical

    Key finding: Here, we used regularized regression approaches with an elastic net penalty for best subset selection of multiregional information from AV45-PET, FDG-PET and volumetric MRI data to predict conversion from MCI to AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2015-05-21

    High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents

    ✓ Peer-reviewed Prevention and risk Biochimica et biophysica acta

    Key finding: The situation is compounded by the fact that apart from the direct costs associated with overweight pathology, obesity presents itself with a number of comorbidities, including an increased risk for the development of neurodegenerative disorders. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2015-05-20

    A pilot study to assess effects of long-term inhalation of airborne particulate matter on early Alzheimer-like changes in the mouse brain

    ✓ Peer-reviewed Biomarkers PloS one

    Key finding: Exposure to air pollutants, including particulate matter, results in activation of the brain inflammatory response and Alzheimer disease (AD)-like pathology in dogs and humans.

    Full summary, score breakdown and related studies → Original source

  15. 2015-05-19

    Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

    ✓ Peer-reviewed Mild cognitive impairment Nature communications

    Key finding: We show that baseline CSF ferritin levels were negatively associated with cognitive performance over 7 years in 91 cognitively normal, 144 mild cognitive impairment (MCI) and 67 AD subjects, and predicted MCI conversion to AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2015-05-18

    Down syndrome: Cognitive and behavioral functioning across the lifespan

    ✓ Peer-reviewed Down syndrome and Alzheimer's American journal of medical genetics. Part C, Seminars in medical genetics

    Key finding: This review updates what is known about the cognitive and behavioral phenotypes associated with DS across the lifespan. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2015-05-15

    CSF proteins and resting-state functional connectivity in Parkinson disease

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Participants with PD had significantly reduced sensorimotor functional connectivity, which correlated with reduced CSF levels of α-synuclein. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2015-05-15

    Long-term PM2.5 Exposure and Neurological Hospital Admissions in the Northeastern United States

    ✓ Peer-reviewed Risk factors Environmental health perspectives

    Key finding: We found strong evidence of association for all three outcomes. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →