Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 11,526–11,550 of 27,380 studies, newest first · page 462 of 1096.
June 2020 25
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2020-06-21
BHA-CS: A novel cognitive composite for Alzheimer's disease and related disorders
68/100 ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's & dementia (Amsterdam, Netherlands)
Key finding: The BHA-CS was accurate at detecting cognitive impairment and exhibited excellent long-term stability. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-21
Cerebrospinal fluid irisin correlates with amyloid-β, BDNF, and cognition in Alzheimer's disease
54/100 ✓ Peer-reviewed Tau biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)
Key finding: CSF irisin correlated positively with BDNF, Aβ42, and MMSE scores, but not with CSF total tau. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-06-20
The Nuts and Bolts of Utilizing Telemedicine in Nursing Homes - The GeriCare@North Experience
43/100 ✓ Peer-reviewed Health systems and care delivery Journal of the American Medical Directors Association
Key finding: There were 1673 teleconsultations conducted with 850 unique patients. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-19
Actigraphy-estimated sleep and 24-hour activity rhythms and the risk of dementia
59/100 ✓ Peer-reviewed Long-term cohort studies Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: During follow-up, 60 individuals developed dementia, of which 49 had Alzheimer's disease (AD). +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-18
Using amyloid PET imaging to diagnose Alzheimer's disease in patients with multiple sclerosis
39/100 ✓ Peer-reviewed Brain scans and imaging Journal of neurology
Key finding: Two patients were diagnosed with AD based on positive Amyloid PET imaging and were subsequently started on cholinesterase inhibitor treatment. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-18
Therapeutic Effects of Transplanted Exosomes Containing miR-29b to a Rat Model of Alzheimer's Disease
43/100 ✓ Peer-reviewed Risk genes beyond APOE Frontiers in neuroscience
Key finding: The expression of miR-29 family is significantly reduced in AD, suggesting a part for the family members in pathogenesis of the disease. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-17
Lithium - past, present, future
39/100 ✓ Peer-reviewed Drug development International journal of psychiatry in clinical practice
Key finding: The history of medical and psychiatric use of lithium dates back to more than one and a half-century ago. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-17
Celebrating 30 years of the Australian Health Promotion Association: Reflecting back to look forward
25/100 ✓ Peer-reviewed Health systems and care delivery Health Promotion Journal of Australia
Key finding: A Life member is defined as a member who has given outstanding and distinguished service to the Association and to health promotion in Australia; where as a Fellow is a member who is regarded as having made a significant contribution to the purposes and objectives of the Association and to health promotion in Australia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-17
Why Loneliness Interventions Are Unsuccessful: A Call for Precision Health
45/100 ✓ Peer-reviewed Digital health tools Advances in geriatric medicine and research
Key finding: We urge the field to rethink metrics to account for diverse intra-individual experiences and trajectories of loneliness.
Full summary, score breakdown and related studies → Original source
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2020-06-17
Dementia care and COVID-19 pandemic: a necessary digital revolution
49/100 ✓ Peer-reviewed Digital health tools Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Key finding: On the other hand, international dementia experts have recommended to provide urgently worldwide support for people living with dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-17
Ambient Air Pollution Increases the Risk of Cerebrovascular and Neuropsychiatric Disorders through Induction of Inflammation and Oxidative Stress
55/100 ✓ Peer-reviewed Caregiving International journal of molecular sciences
Key finding: The Lancet Commission on pollution and health concludes that air pollution is the leading environmental cause of global disease and premature death. +2 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-17
Healthy lifestyle and the risk of Alzheimer dementia: Findings from 2 longitudinal studies
77/100 ✓ Peer-reviewed Prevention and risk Neurology
Key finding: A healthy lifestyle as a composite score is associated with a substantially lower risk of Alzheimer's dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-16
Safety of pharmacologic interventions for neuropsychiatric symptoms in dementia: a systematic review and network meta-analysis
69/100 ✓ Peer-reviewed Treatments BMC geriatrics
Key finding: Although antipsychotics were associated with greater harm than antidepressants and anticonvulsants in subgroups of persons with dementia, medications used in lieu of antipsychotics for treating neuropsychiatric symptoms in dementia, such as anticonvulsants and dextromethorphan-quinidine, were also associated with harm. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-15
Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease
59/100 ✓ Peer-reviewed Mild cognitive impairment Clinical epigenetics
Key finding: Our work shows that peripheral differential methylation between age-matched subjects with AD relative to healthy controls will provide opportunities to further investigate and validate differential methylation as a surrogate of disease. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-06-13
Focus on the Role of NLRP3 Inflammasome in Diseases
41/100 ✓ Peer-reviewed Disease mechanisms International journal of molecular sciences
Key finding: They have been associated with several inflammatory disorders. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-06-12
The Role of Resting-State Network Functional Connectivity in Cognitive Aging
39/100 ✓ Peer-reviewed Brain scans and imaging Frontiers in aging neuroscience
Key finding: Aging is associated with disruptions in the resting-state functional architecture of the brain. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-12
TREM2 Overexpression Attenuates Cognitive Deficits in Experimental Models of Vascular Dementia
39/100 ✓ Peer-reviewed TREM2 and immune genetics Neural plasticity
Key finding: Interestingly, overexpression of TREM2 by intracerebroventricular injection of a lentiviral vector that encoded TREM2 (LV-TREM2) significantly improved the spatial learning and memory and attenuated the hippocampal neural loss in VD mice. +2 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-12
Triggering receptor expressed on myeloid cells 2 activation downregulates toll-like receptor 4 expression and ameliorates cognitive impairment in the Aβ1-42 -induced Alzheimer's disease mouse model
39/100 ✓ Peer-reviewed TREM2 and immune genetics Synapse (New York, N.Y.)
Key finding: Increasing evidence suggests that changes in the triggering receptor expressed on myeloid cells 2 (TREM2) is closely correlated with the pathological development of Alzheimer's disease (AD). +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-12
A video-game based cognitive training for breast cancer survivors with cognitive impairment: A prospective randomized pilot trial
69/100 ✓ Peer-reviewed Prevention trials Breast (Edinburgh, Scotland)
Key finding: A program of cognitive training improves cognitive functioning over time. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-12
Shifting paradigms: The central role of microglia in Alzheimer's disease
40/100 ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of disease
Key finding: Parallel transcriptome and histology studies at the single-cell level revealed a rich palette of microglial states affected by disease status and genetic risk factors. +3 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-11
Optical coherence tomography angiography as a potential screening tool for cerebral small vessel diseases
54/100 ✓ Peer-reviewed Brain scans and imaging Alzheimer's research & therapy
Key finding: The SVCI group showed lower CD in the temporal quadrant of the RPC network compared to the CN group (mean (SD), 42.34 (6.29) vs 48.45 (7.08); p = 0.001). +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-11
Association of Neighborhood-Level Disadvantage With Alzheimer Disease Neuropathology
64/100 ✓ Peer-reviewed Risk factors JAMA Network Open
Key finding: The sample consisted of 447 decedents (249 men [56%]; mean [SD] age, 80.3 [9.5] years; median year of death, 2011) spanning 24 years of donation. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-11
A Machine Learning Approach for the Differential Diagnosis of Alzheimer and Vascular Dementia Fed by MRI Selected Features
56/100 ✓ Peer-reviewed Brain scans and imaging Frontiers in neuroinformatics
Key finding: ML predictions were compared with the diagnosis evidence from a 3-year clinical follow-up. +1 more finding
Full summary, score breakdown and related studies → Original source
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2020-06-10
APOE Alleles and Diet in Brain Aging and Alzheimer's Disease
39/100 ✓ Peer-reviewed Genetics Frontiers in aging neuroscience
Key finding: The association of APOE4 with glucose dysregulation and body weight promotes many aging-associated diseases. +4 more findings
Full summary, score breakdown and related studies → Original source
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2020-06-10
Efficacy of lifestyle and psychosocial interventions in reducing cognitive decline in older people: Systematic review
66/100 ✓ Peer-reviewed Prevention trials Ageing research reviews
Key finding: We narratively synthesised evidence, prioritising results from studies rated as at lower Risk of Bias (ROB) and assigning Centre for Evidence Based Medicine grades. +2 more findings
Full summary, score breakdown and related studies → Original source
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