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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,776–12,800 of 27,380 studies, newest first · page 512 of 1096.

June 2019 22

  1. 2019-06-06

    Association of 3-Year Multidomain Intervention and Omega-3 Supplementation with Frailty Incidence

    ✓ Peer-reviewed Treatments Journal of the American Geriatrics Society

    Key finding: In community-dwelling older persons, the combination of a long-term lifestyle MI and omega-3 supplementation did not reduce frailty level or incidence. +2 more findings

  2. 2019-06-05

    Tau Positron Emission Tomography Binding Is Not Elevated in HIV-Infected Individuals

    ✓ Peer-reviewed Brain scans and imaging The Journal of infectious diseases

    Key finding: Older HIV-positive individuals are not at increased risk of tau-mediated neurodegeneration.

  3. 2019-06-04

    The costs of dementia subtypes to California Medicare fee-for-service, 2015

    ✓ Peer-reviewed Costs and economics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: 3,001,987 Medicare beneficiaries were identified, of which 8.2% had a dementia diagnosis. +4 more findings

  4. 2019-06-04
  5. 2019-06-04

    Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)

    ✓ Peer-reviewed Prevention trials Alzheimer's research & therapy

    Key finding: The FINGER MRI exploratory sub-study did not show significant differences between the intervention and control groups on changes in regional brain volumes, regional cortical thicknesses, or WML volume after 2 years in at-risk elderly without substantial impairment. +4 more findings

  6. 2019-06-04

    Measuring gait speed to better identify prodromal dementia

    ✓ Peer-reviewed Caregiving Experimental gerontology

    Key finding: Of 39 studies selected, including overall 57,456 participants, 33 reported a significant association between gait speed and cognitive outcomes, including dementia.

  7. 2019-06-03

    Single-cell transcriptomics unveils gene regulatory network plasticity

    ✓ Peer-reviewed Genetics Genome biology

    Key finding: We devise a conceptually different computational framework based on a holistic view, where single-cell datasets are used to infer global, large-scale regulatory networks. +3 more findings

  8. 2019-06-03

    Endo-lysosomal dysregulations and late-onset Alzheimer's disease: impact of genetic risk factors

    ✓ Peer-reviewed TREM2 and immune genetics Molecular neurodegeneration

    Key finding: Autophagy and endolysosomal homeostasis need to be maintained throughout life as they are major cellular mechanisms involved in both the production of toxic amyloid peptides and the clearance of misfolded or aggregated proteins. +3 more findings

  9. 2019-06 month only

    HDL from an Alzheimer's disease perspective

    ✓ Peer-reviewed Vascular contributions Current opinion in lipidology

    Key finding: RECENT FINDINGS: Many epidemiological studies have observed that circulating HDL levels associate with decreased Alzheimer's disease risk. +4 more findings

  10. 2019-06-01

    Deaths: Leading Causes for 2017

    ✓ Peer-reviewed Disparities National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System

    Key finding: In 2017, the 10 leading causes of death were, in rank order: Diseases of heart; Malignant neoplasms; Accidents (unintentional injuries); Chronic lower respiratory diseases; Cerebrovascular diseases; Alzheimer disease; Diabetes mellitus; Influenza and pneumonia; Nephritis, nephrotic syndrome and nephrosis; and Intentional self-harm (suicide).

  11. 2019-06-01

    Prevention of tau seeding and propagation by immunotherapy with a central tau epitope antibody

    ✓ Peer-reviewed Drug development Brain : a journal of neurology

    Key finding: Second, by using K18 P301L tau fibrils to induce pathology, we further demonstrated that antibody D was also capable of blocking the progression of tau pathology to distal brain regions. +1 more finding

  12. 2019-06-01

    Diet and Inflammation in Cognitive Ageing and Alzheimer's Disease

    ✓ Peer-reviewed Prevention trials Current nutrition reports

    Key finding: Nutrition is known to modulate the immune system and may alter neuroinflammatory processes implicated in the pathogenesis of Alzheimer's disease (AD) and progression of neurodegeneration.

  13. 2019-06-01
  14. 2019-06-01

    The relationship between sleep duration, cognition and dementia: a Mendelian randomization study

    ✓ Peer-reviewed Long-term cohort studies International journal of epidemiology

    Key finding: Linear MR suggested that each additional hour/day of sleep was associated with 1% [95% confidence interval (CI) = 0-2%; P = 0.008] slower reaction time and 3% more errors in visual-memory test (95% CI = 0-6%; P = 0.05). +3 more findings

  15. 2019-06-01

    Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism

    ✓ Peer-reviewed TREM2 and immune genetics EMBO molecular medicine

    Key finding: A number of variants in genes selectively expressed in microglia are associated with an increased risk for neurodegenerative diseases such as Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD). +3 more findings

  16. 2019-06-01

    Obstructive sleep apnea and longitudinal Alzheimer's disease biomarker changes

    ✓ Peer-reviewed Mild cognitive impairment Sleep

    Key finding: Study objectives To determine the effect of self-reported clinical diagnosis of obstructive sleep apnea (OSA) on longitudinal changes in brain amyloid PET and CSF biomarkers (Aβ42, T-tau, and P-tau) in cognitively normal (NL), mild cognitive impairment (MCI), and Alzheimer's disease (AD) elderly. +1 more finding

  17. 2019-06-01

    A multicentre longitudinal study of flortaucipir (18F) in normal ageing, mild cognitive impairment and Alzheimer's disease dementia

    ✓ Peer-reviewed Caregiving Brain : a journal of neurology

    Key finding: There was a statistically significant increase in the global estimate of cortical tau burden as measured by standardized uptake value ratio (SUVr) from baseline to 18 months in amyloid-β+ but not amyloid-β- subjects (least squared mean change in flortaucipir SUVr : 0.0524 ± 0.0085, P < 0.0001 and 0.0007 ± 0.0024 P = 0.7850, respectively), and a significant association between magnitude of SUVr increase and baseline tau burden. +3 more findings

  18. 2019-06-01

    Physical Activity, Cognition, and Brain Outcomes: A Review of the 2018 Physical Activity Guidelines

    ✓ Peer-reviewed Prevention and risk Medicine and science in sports and exercise

    Key finding: There is moderate-to-strong support that PA benefits cognitive functioning during early and late periods of the life span and in certain populations characterized by cognitive deficits. +2 more findings

  19. 2019-06-01

    Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

    ✓ Peer-reviewed Prevention and risk Brain : a journal of neurology

    Key finding: LATE-NC is a common TDP-43 proteinopathy, associated with an amnestic dementia syndrome that mimicked Alzheimer's-type dementia in retrospective autopsy studies. +3 more findings

  20. 2019-06-01
  21. 2019-06-01

    Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype

    ✓ Peer-reviewed Genetics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Estimates of AD disease duration become more accurate if age, sex, setting, APOE, and cerebrospinal fluid tau are taken into account. +1 more finding

  22. 2019-06-01

    Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia

    ✓ Peer-reviewed Biomarkers JAMA

    Key finding: Analyses measured the associations between predictor variables and the memory score, and whether AT(N) biomarker profiles significantly improved prediction of memory z score rates of change beyond a model with clinical and genetic variables only. +2 more findings

May 2019 3

  1. 2019-05-31

    Association Between Relevant Co-Morbidities and Dementia With Atrial Fibrillation-A National Study

    ✓ Peer-reviewed Risk factors Archives of medical research

    Key finding: Totally 30,332 patients (5.6%) were diagnosed with dementia during the follow-up, with 14,097 men (4.9%) and 16,235 women (6.5%). +4 more findings

  2. 2019-05-31

    Diagnosis of Alzheimer's Disease via Multi-Modality 3D Convolutional Neural Network

    ✓ Peer-reviewed Digital health tools Frontiers in neuroscience

    Key finding: Finally, the results have demonstrated that (1) segmentation is not a prerequisite when using a CNN for the classification, (2) the combination of two modality imaging data generates better results.

  3. 2019-05-31

    Lifespan Intellectual Factors, Genetic Susceptibility, and Cognitive Phenotypes in Aging: Implications for Interventions

    ✓ Peer-reviewed Prevention trials Frontiers in aging neuroscience

    Key finding: Numerous population-based studies have suggested that early-life educational attainments and socioeconomic status, midlife work complexity and social engagements, late-life leisure activities (social, physical, and mentally-stimulating activities), certain personality traits (e.g., high neuroticism and low conscientiousness), and depression significantly affect late-life cognitive phenotypes.

Browse the library by subject, with the full score breakdown →