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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,901–10,925 of 27,380 studies, newest first · page 437 of 1096.

December 2020 17

  1. 2020-12-01

    Concomitant Cholinesterase Inhibitor and Anticholinergic Drug Use Among Older Adults With Dementia

    ✓ Peer-reviewed Health systems and care delivery Innovation in Aging

    Key finding: Anticholinergic medications (ACh) are frequently prescribed to older adults despite being associated with impaired physical functioning. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2020-12-01

    A patient journey analysis: Identification and treatment of dementia with Lewy bodies

    ✓ Peer-reviewed Health systems and care delivery Alzheimer s & Dementia

    Key finding: Percentages of patients with imaging tests, DLB symptoms, diagnoses and treatments for DLB increased as patients’ first DLB diagnosis neared and occurred at lower percentages 7‐12 months after initial diagnosis.

    Full summary, score breakdown and related studies → Original source

  3. 2020-12-01

    Healthcare costs among patients with dementia‐related psychosis: Comparing dementia with Lewy bodies with other dementias

    ✓ Peer-reviewed Health systems and care delivery Alzheimer s & Dementia

    Key finding: DLB patients had higher medication and psychosis‐related costs than DRP patients who had other dementias. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2020-12-01

    Prevalence of Diagnosed Alzheimer’s Disease and Related Dementias in Medicare Advantage

    ✓ Peer-reviewed Health systems and care delivery Innovation in Aging

    Key finding: A third of Medicare beneficiaries are enrolled in Medicare Advantage (MA); however, little is known about MA beneficiaries diagnosed with Alzheimer’s disease and related dementias (AD/ADRD).

    Full summary, score breakdown and related studies → Original source

  5. 2020-12-01

    Regional Variation in Healthcare Use Among Medicare Beneficiaries With Alzheimer’s Disease and Related Dementias

    ✓ Peer-reviewed Health systems and care delivery Innovation in Aging

    Key finding: Controlling for beneficiary, local, and state characteristics, we found the following factors to be associated with beneficiaries spending less time in nursing homes: fewer nursing home beds in the county, higher state Medicaid long-term care spending for home and community-based services (HCBS), and state use of Certificate of Need laws. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2020-12-01

    Stage-specific links between plasma neurofilament light and imaging biomarkers of Alzheimer's disease

    ✓ Peer-reviewed Long-term cohort studies Brain : a journal of neurology

    Key finding: It remains uncertain, however, how it relates to amyloid and tau pathology or neurodegeneration across the Alzheimer's disease continuum. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-12-01

    Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis

    ✓ Peer-reviewed Tau biomarkers Science translational medicine

    Key finding: YKL-40, a primarily astrocytic protein encoded by the gene Chi3l1 , is a widely studied cerebrospinal fluid biomarker that increases with aging and early in AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2020-12-01

    Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE

    ✓ Peer-reviewed TREM2 and immune genetics The Journal of experimental medicine

    Key finding: Here, we establish isogenic human ESC-derived microglia-like cell lines (hMGLs) harboring AD variants in CD33, INPP5D, SORL1, and TREM2 loci and curate a comprehensive atlas comprising ATAC-seq, ChIP-seq, RNA-seq, and proteomics datasets. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2020-12-01

    The accumulation rate of tau aggregates is higher in females and younger amyloid-positive subjects

    ✓ Peer-reviewed Mild cognitive impairment Brain : a journal of neurology

    Key finding: We found that accelerated increase in tau-PET signal was observed in amyloid-β-positive mild cognitive impairment (3.0 ± 5.3%) and Alzheimer's disease dementia (2.9 ± 5.7%), respectively, when compared to either amyloid-β-negative cognitively unimpaired (0.4 ± 2.7%), amyloid-β-negative mild cognitive impairment (-0.4 ± 2.3%) or amyloid-β-positive cognitively unimpaired (1.2 ± 2.8%). +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2020-12-01

    Longitudinal plasma p-tau217 is increased in early stages of Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Brain : a journal of neurology

    Key finding: Preclinical (amyloid-β-positive cognitively unimpaired, n = 62) and prodromal (amyloid-β-positive mild cognitive impairment, n = 49) Alzheimer's disease had accelerated p-tau217 compared to amyloid-β-negative cognitively unimpaired (β = 0.56, P < 0.001, using linear mixed effects models) and amyloid-β-negative mild cognitive impairment patients (β = 0.67, P < 0.001), respectively. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2020-12-01

    Balance and gait performance in older adults with early-stage cognitive impairment

    ✓ Peer-reviewed Digital health tools European journal of physical and rehabilitation medicine

    Key finding: It is a piece of evidence that cognitive dysfunction, even in early stage of memory decline, may have some bad impact on balance and gait regardless of the effect of musculoskeletal problems. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2020-12-01

    Differential insular cortex sub-regional atrophy in neurodegenerative diseases: a systematic review and meta-analysis

    ✓ Peer-reviewed Digital health tools Brain imaging and behavior

    Key finding: As a result, its centrality in the brain confers high metabolic demands predisposing it to dysfunction in disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2020-12-01

    Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex

    ✓ Peer-reviewed Digital health tools Brain : a journal of neurology

    Key finding: We aimed to develop a novel epigenetic clock that performs optimally in human cortex tissue and has the potential to identify phenotypes associated with biological ageing in the brain. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2020-12-01

    Estimates of the Association of Dementia With US Mortality Levels Using Linked Survey and Mortality Records

    ✓ Peer-reviewed Disparities JAMA neurology

    Key finding: Of the 7342 total sample, 4348 participants (60.3%) were women. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2020-12-01

    Prevalence, risk factors, and management of dementia and mild cognitive impairment in adults aged 60 years or older in China: a cross-sectional study

    ✓ Peer-reviewed Prevention and risk The Lancet. Public health

    Key finding: Overall age-adjusted and sex-adjusted prevalence was estimated to be 6·0% (95% CI 5·8-6·3) for dementia, 3·9% (3·8-4·1) for Alzheimer's disease, 1·6% (1·5-1·7) for vascular dementia, and 0·5% (0·5-0·6) for other dementias. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2020-12-01

    Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment

    ✓ Peer-reviewed Treatments JAMA neurology

    Key finding: Compared with participants who learned that they had a not elevated amyloid result, individuals who learned of an elevated amyloid result were no more likely to experience short-term increases in depression (mean [SD] change in the Geriatric Depression Scale score, 0.02 [1.3] vs 0.04 [1.3]; P = .90), anxiety (mean [SD] change in State-Trait Anxiety Inventory score, -0.02 [3.2] vs -0.15 [3.0]; P = .65), or suicidality (mean [SD] change in the Columbia Suicide Severity Rating Scale score, 0.0 [0.4] vs -0.01 [0.5]; P = .67). +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2020-12-01

    Association of APOE4 and Clinical Variability in Alzheimer Disease With the Pattern of Tau- and Amyloid-PET

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Clinical phenotypes are associated with differential patterns of tau but not amyloid pathology. +2 more findings

    Full summary, score breakdown and related studies → Original source

November 2020 8

  1. 2020-11-30

    Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease

    ✓ Peer-reviewed Genetics Nature communications

    Key finding: Here, we investigate the population structure of live microglia purified from human cerebral cortex samples obtained at autopsy and during neurosurgical procedures. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2020-11-30

    Head-to-head comparison of clinical performance of CSF phospho-tau T181 and T217 biomarkers for Alzheimer's disease diagnosis

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: N-p-tau217 and N-p-tau181 could improve diagnostic accuracy in prodromal-AD and clinical trial recruitment as both identify Aβ pathophysiology and differentiate early MCI-AD better than Mid-p-tau181. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2020-11-30

    Individualized prognosis of cognitive decline and dementia in mild cognitive impairment based on plasma biomarker combinations

    ✓ Peer-reviewed Long-term cohort studies Nature aging

    Key finding: A total of 573 patients with MCI from the Swedish BioFINDER study and the Alzheimer's Disease Neuroimaging Initiative (ADNI) were included in the study. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2020-11-30

    Automatic dementia screening and scoring by applying deep learning on clock-drawing tests

    ✓ Peer-reviewed Digital health tools Scientific reports

    Key finding: The outcome of our work is a standardized and digital estimation of the dementia screening result and severity level for an individual.

    Full summary, score breakdown and related studies → Original source

  5. 2020-11-29

    Dietary Habits and Risk of Early-Onset Dementia in an Italian Case-Control Study

    ✓ Peer-reviewed Prevention and risk Nutrients

    Key finding: A high intake (>400 g/day) of dairy products was also associated with excess risk. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2020-11-29

    Variability and Potential Determinants of Assisted Living State Regulatory Stringency

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Medical Directors Association

    Key finding: Factors associated with domain-specific and overall regulatory stringency were identified. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-11-28

    Evaluation of a visual interpretation method for tau-PET with 18F-flortaucipir

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Global visual scores were reliable, correlated with global cortical 18F-flortaucipir standardized uptake value ratio (SUVR) and were associated with clinical diagnosis and amyloid status. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2020-11-28

    Enhancing shared and surrogate decision making for people living with dementia: A systematic review of the effectiveness of interventions

    ✓ Peer-reviewed End-of-life care Health expectations : an international journal of public participation in health care and health policy

    Key finding: Decision-making interventions typically consist of multiple components which aim to establish preferences for future health care.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →