Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 24,026–24,050 of 27,380 studies, newest first · page 962 of 1096.
July 2004 25
-
2004-07-27
Hereditary dementia with intracerebral hemorrhages and cerebral amyloid angiopathy
41/100 ✓ Peer-reviewed Risk genes beyond APOE Neurology
Key finding: Neuropathologic examination revealed Alzheimer-type changes with Abeta in neuritic plaques and vessel walls, but the cognitive profile of the patients differed from that in AD, as the visuoconstructive functions and verbal fluency were well preserved even in the moderate stage of the disease. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-22
General practitioners' knowledge, confidence and attitudes in the diagnosis and management of dementia
65/100 ✓ Peer-reviewed Caregiving Age and ageing
Key finding: Educational support for general practitioners should concentrate on epidemiological knowledge, disclosure of the diagnosis and management of behaviour problems in dementia.
Full summary, score breakdown and related studies → Original source
-
2004-07-21
ABCA1 Is Required for Normal Central Nervous System ApoE Levels and for Lipidation of Astrocyte-secreted apoE
40/100 ✓ Peer-reviewed Genetics Journal of Biological Chemistry
Key finding: We found that Abca1-/- mice have greatly decreased apoE levels in both the cortex (80% reduction) and the CSF (98% reduction). +3 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Benzodiazepine use and hip fractures in the elderly: who is at greatest risk?
48/100 ✓ Peer-reviewed Digital health tools Archives of internal medicine
Key finding: The incidence of hip fracture appears to be associated with benzodiazepine use. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: a randomized controlled trial
79/100 ✓ Peer-reviewed Clinical trials JAMA
Key finding: This double-blind randomized trial does not support the hypothesis that the use of soy protein supplement containing isoflavones improves cognitive function, bone mineral density, or plasma lipids in healthy postmenopausal women when started at the age of 60 years or later. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2004-07-01
The efficacy of donepezil in the treatment of neuropsychiatric symptoms in Alzheimer disease
77/100 ✓ Peer-reviewed Treatments Neurology
Key finding: Donepezil has significant efficacy in the treatment of neuropsychiatric symptoms in patients with mild to moderate AD. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK)
36/100 ✓ Peer-reviewed Drug development Journal of neurochemistry
Key finding: These findings extend the number of candidate protein kinases for the hyperphosphorylation of tau in Alzheimer's disease and other neurodegenerative disorders.
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Medial temporal lobe function and structure in mild cognitive impairment
40/100 ✓ Peer-reviewed Brain scans and imaging Annals of neurology
Key finding: Moreover, those who subsequently declined over the 2.5 years of clinical follow-up (44% of the subjects) activated a significantly greater extent of the right PHG during encoding, despite equivalent memory performance.
Full summary, score breakdown and related studies → Original source
-
2004-07-01
EEG dynamics in patients with Alzheimer's disease
52/100 ✓ Peer-reviewed Brain scans and imaging Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Key finding: These abnormalities are thought to be associated with functional disconnections among cortical areas resulting from death of cortical neurons, axonal pathology, cholinergic deficits, etc. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Physician recognition of cognitive impairment: evaluating the need for improvement
66/100 ✓ Peer-reviewed Vascular contributions Journal of the American Geriatrics Society
Key finding: Medical record documentation reflects physician recognition of dementia, yet physicians are aware of, but have not documented, many patients with milder cognitive impairment. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Molecular pharmacology of glutamate transporters, EAATs and VGLUTs
36/100 ✓ Peer-reviewed Vascular contributions Brain research. Brain research reviews
Key finding: Examination of EAATs and VGLUTs in brain preparations and by heterologous expression of the various cloned subtypes shows these two transporter families differ in many of their functional properties including substrate specificity and ion requirements. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Moderate renal impairment and risk of dementia among older adults: the Cardiovascular Health Cognition Study
50/100 ✓ Peer-reviewed Vascular contributions Journal of the American Society of Nephrology : JASN
Key finding: Renal impairment is associated with an increased risk of carotid atherosclerosis and stroke, determinants of cognitive dysfunction and dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Anatomical MRI study of borderline personality disorder patients
36/100 ✓ Peer-reviewed Hippocampus size on brain scans Psychiatry research
Key finding: Hippocampal volume reduction has been reported in patients with borderline personality disorder (BPD), and is hypothesized to be associated with traumatic childhood experiences. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Hippocampal volume, memory, and cortisol status in major depressive disorder: effects of treatment
43/100 ✓ Peer-reviewed Hippocampus size on brain scans Biological psychiatry
Key finding: Medication-free nonelderly depressed outpatients without alcohol dependence or adverse experiences in childhood had normal hippocampal volume. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
The amygdala is enlarged in children but not adolescents with autism; the hippocampus is enlarged at all ages
43/100 ✓ Peer-reviewed Hippocampus size on brain scans The Journal of neuroscience : the official journal of the Society for Neuroscience
Key finding: Thus, the amygdala in children with autism is initially larger, but does not undergo the age-related increase observed in typically developing children. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Forgoing artificial nutrition and hydration in nursing home patients with dementia: patients, decision making, and participants
36/100 ✓ Peer-reviewed End-of-life care Alzheimer disease and associated disorders
Key finding: On the basis of these results, we recommend that discussions that include NHPs, family members, and nurses concerning decisions about possible future situations be held on a regular basis. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Psychiatric aspects of Parkinson's disease--an update
43/100 ✓ Peer-reviewed Clinical safety Journal of neurology
Key finding: In patients with dementia associated with PD cognitive functioning and behavioural problems appear to respond to cholinesterase inhibitors, such as rivastigmine or donepezil.
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Herbert M. Sommers, MD
25/100 ✓ Peer-reviewed Risk factors Archives of Pathology & Laboratory Medicine
Key finding: Accompanied by Washington Winn, we paid one last visit to present him with a copy of the just published 5th edition of the Color Atlas. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Microglia and Alzheimer's disease pathogenesis
46/100 ✓ Peer-reviewed Inflammation and the immune system Journal of neuroscience research
Key finding: The concept of detrimental neuroinflammation has gained a strong foothold in the AD arena and is being expanded to other neurodegenerative diseases. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology
50/100 ✓ Peer-reviewed Brain tissue and pathology The Journal of clinical investigation
Key finding: Together with amyloid beta (Abeta) plaques and neuronal and synaptic loss, NFTs constitute the primary pathological hallmarks of Alzheimer disease (AD). +3 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Frontal assessment battery and differential diagnosis of frontotemporal dementia and Alzheimer disease
51/100 ✓ Peer-reviewed Cognitive tests and assessment Archives of neurology
Key finding: The different distribution of pathologic features in frontotemporal dementia (FTD) and Alzheimer disease (AD) predicts a predominant dysexecutive syndrome in FTD. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Neuropathology provides clues to the pathophysiology of Gaucher disease
47/100 ✓ Peer-reviewed Lewy body dementia Molecular genetics and metabolism
Key finding: While these findings were common to all three GD phenotypes, the extent of the changes varied depending on the severity of disease. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of beta-amyloid deposits
39/100 ✓ Peer-reviewed Down syndrome and Alzheimer's The American journal of pathology
Key finding: Immunoelectron microscopy of CLAC-positive SP showed labeling of fibrils that are more loosely dispersed compared to typical amyloid fibrils in CLAC-negative SP. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Trisomy 21 and the brain
40/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of neuropathology and experimental neurology
Key finding: This developmental failure is thought to result in mental retardation.
Full summary, score breakdown and related studies → Original source
-
2004-07-01
Medial temporal lobe atrophy on MRI predicts dementia in patients with mild cognitive impairment
55/100 ✓ Peer-reviewed Risk factors Neurology
Key finding: The mean follow-up period for the cohort was 34 months. +2 more findings
Full summary, score breakdown and related studies → Original source
Browse the library by subject, with the full score breakdown →