alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,701–10,725 of 27,380 studies, newest first · page 429 of 1096.

January 2021 25

  1. 2021-01-05

    Lack of association between acute stroke, post-stroke dementia, race, and β-amyloid status

    ✓ Peer-reviewed Disparities NeuroImage. Clinical

    Key finding: A total of 243 participants were enrolled, 81 of which had a recent ischemic stroke. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-01-05

    Dysbiosis and Alzheimer's Disease: Cause or Treatment Opportunity?

    ✓ Peer-reviewed Disease mechanisms Cellular and molecular neurobiology

    Key finding: Recent investigations have increased the interest on the connection between the microorganisms inhabiting the gut (gut microbiota) and human health. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-01-05

    Association of Aβ deposition and regional synaptic density in early Alzheimer's disease: a PET imaging study with [11C]UCB-J

    ✓ Peer-reviewed Disease mechanisms Alzheimer's research & therapy

    Key finding: Our findings lend support to a model in which fibrillar Aβ is still accumulating in the early stages of clinical disease but approaching a relative plateau, a point at which Aβ may uncouple from neurodegenerative processes including synaptic loss. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-01-05

    N6-methyladenosine dynamics in neurodevelopment and aging, and its potential role in Alzheimer's disease

    ✓ Peer-reviewed Brain tissue and pathology Genome biology

    Key finding: We show that m 6 A modification displays temporal and spatial dynamics during neurodevelopment and aging. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-01-05

    Blood-Brain Barrier Opening with MRI-guided Focused Ultrasound Elicits Meningeal Venous Permeability in Humans with Early Alzheimer Disease

    ✓ Peer-reviewed Brain scans and imaging Radiology

    Key finding: Three women (aged 61, 72, and 73 years) consecutively enrolled in the trial successfully completed repeated focused ultrasound-induced BBB opening of the hippocampus and entorhinal cortex.

    Full summary, score breakdown and related studies → Original source

  6. 2021-01-05

    Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study

    ✓ Peer-reviewed Getting a diagnosis Acta neuropathologica

    Key finding: The category of neocortical LP according to the LPC system was associated with a 5.9 OR (p < 0.0001) of dementia in the 134 NBTR cases and a 3.14 OR (p = 0.0001) in the 202 UPBB cases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2021-01-04

    Nuclear Ubiquitin-Proteasome Pathways in Proteostasis Maintenance

    ✓ Peer-reviewed Disease mechanisms Biomolecules

    Key finding: PQC pathways have been first described in the cytoplasm and the endoplasmic reticulum, however, accumulating evidence indicates that the nucleus is an important PQC compartment for ubiquitination and proteasomal degradation of not only nuclear, but also cytoplasmic proteins.

    Full summary, score breakdown and related studies → Original source

  8. 2021-01-04

    Exercise interventions for older adults with Alzheimer's disease: a systematic review and meta-analysis protocol

    ✓ Peer-reviewed Prevention trials Systematic reviews

    Key finding: This review is anticipated to yield clinically meaningful insight on the specific value of exercise for older adults with AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-01-04

    A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease

    ✓ Peer-reviewed Drug development Alzheimer's research & therapy

    Key finding: We found that both Adu and SUS reduced the total plaque area in the hippocampus to a similar degree, with no additive effect in the combination treatment (SUS+Adu). +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-01-04

    Assessment of Advanced Glycation End Products and Receptors and the Risk of Dementia

    ✓ Peer-reviewed Long-term cohort studies JAMA network open

    Key finding: Advanced glycation end products (AGEs) and their receptor (RAGE) are implicated in the pathophysiological processes of dementia and potentially underlie the association of diabetes with neurodegeneration. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2021-01-04

    Temporal Trends in Incidence Rates of Lower Extremity Amputation and Associated Risk Factors Among Patients Using Veterans Health Administration Services From 2008 to 2018

    ✓ Peer-reviewed Disparities JAMA network open

    Key finding: Compared with men, women had decreased risk of any LEA (hazard ratio [HR], 0.34 [95% CI, 0.31-0.37]). +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-01-04

    ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response

    ✓ Peer-reviewed Genetics Cell stem cell

    Key finding: ApoE4, a strong genetic risk factor for Alzheimer disease, has been associated with increased risk for severe COVID-19. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2021-01 month only

    Donanemab (LY3002813) dose‐escalation study in Alzheimer's disease

    ✓ Peer-reviewed Treatments Alzheimer's & Dementia: Translational Research & Clinical Interventions

    Key finding: Donanemab was generally well tolerated up to 10 mg/kg. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-01 month only

    Objective subtle cognitive decline and plasma phosphorylated tau181: Early markers of Alzheimer's disease‐related declines

    ✓ Peer-reviewed Biomarkers Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

    Key finding: CU and Obj‐SCD has lower baseline p‐tau181 than MCI and did not differ from one another. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-01-01

    DEMNET: A Deep Learning Model for Early Diagnosis of Alzheimer Diseases and Dementia From MR Images

    ✓ Peer-reviewed Long-term cohort studies IEEE Access

    Key finding: To avoid the problem of class imbalance, the samples should be evenly distributed among the classes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-01-01

    Interaction between Aβ and Tau in the Pathogenesis of Alzheimer's Disease

    ✓ Peer-reviewed Inflammation and the immune system International Journal of Biological Sciences

    Key finding: Studies suggest that the coexistence of Aβ plaques and phosphorylated tau is related to the mechanism by which Aβ facilitates the propagation of tau aggregation in neuritic plaques.

    Full summary, score breakdown and related studies → Original source

  17. 2021 year only

    Cost of Illness of Major Neurocognitive Disorders in India

    ✓ Peer-reviewed Costs and economics Neurology India

    Key finding: The annual cost of care per patient with mild to moderate and severe major MCD was INR 78288 and INR 167808, respectively. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021 year only

    Economic Burden of Alzheimer's Disease Dementia in Japan

    ✓ Peer-reviewed Costs and economics Journal of Alzheimer's disease : JAD

    Key finding: The total healthcare cost of ADD was JPY 1,073 billion, of which 86% (JPY 923 billion) was attributed to healthcare costs other than ADD drug costs (JPY 151 billion). +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2021 year only

    Relationships Between Chronic Pain Stage, Cognition, Temporal Lobe Cortex, and Sociodemographic Variables

    ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD

    Key finding: There were ethnic/race group differences in MoCA scores but no relationships with chronic knee pain stage. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021 year only

    Why Inclusion Matters for Alzheimer's Disease Biomarker Discovery in Plasma

    ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD

    Key finding: In total, 740 proteins were identified of which, 25 differentially-expressed proteins in AD came from comparisons within a single racial and ethnic background group. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2021 year only

    How Do Persons with Young and Late Onset Dementia Die?

    ✓ Peer-reviewed End-of-life care Journal of Alzheimer's disease : JAD

    Key finding: Circumstances of death, symptoms, and treatment appeared to be similar between YOD and LOD, except that persons with LOD had significantly more somatic comorbidities and were admitted to hospital in the last three months of life more often than persons with LOD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021 year only

    Goals of Care Conversations and Subsequent Advance Care Planning Outcomes for People with Dementia

    ✓ Peer-reviewed End-of-life care Journal of Alzheimer's disease : JAD

    Key finding: At time of death, the majority of decedents with dementia had advance directives, health care agents, and previous goals of care conversations with their caregiver. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021 year only

    Factors Associated With Home-Hospice Utilization

    ✓ Peer-reviewed End-of-life care Home healthcare now

    Key finding: We sought to identify patient, provider, and community factors associated with home-hospice use. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2021 year only

    Community Visioning for Innovation in Integrated Dementia Care: Stakeholder Focus Group Outcomes

    ✓ Peer-reviewed Health systems and care delivery Journal of primary care & community health

    Key finding: In searching for innovative options to create more autonomy and better quality of life in dementia care settings, repurposing existing structures, in particular vacant urban malls, may be 1 option for the large sites needed for the European model of dementia villages. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2021 year only

    Home Visit Based Mindfulness Intervention for Vietnamese American Dementia Family Caregivers: A Pilot Feasibility Study

    ✓ Peer-reviewed Caregiving Asian/Pacific Island nursing journal

    Key finding: A total of nine VA family caregivers of PWD participated in this pilot study. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →