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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,576–10,600 of 27,380 studies, newest first · page 424 of 1096.

February 2021 25

  1. 2021-02-03

    Ferroptosis: mechanisms and links with diseases

    ✓ Peer-reviewed Disease mechanisms Signal transduction and targeted therapy

    Key finding: Ferroptosis is an iron-dependent cell death, which is different from apoptosis, necrosis, autophagy, and other forms of cell death. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-02-03

    Cognitive and behavioural flexibility: neural mechanisms and clinical considerations

    ✓ Peer-reviewed Prevention trials Nature reviews. Neuroscience

    Key finding: Cognitive and behavioural flexibility permit the appropriate adjustment of thoughts and behaviours in response to changing environmental demands. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-02-03

    Alzheimer's Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia

    ✓ Peer-reviewed TREM2 and immune genetics Frontiers in immunology

    Key finding: Due to the many limitations to study microglia in situ or isolated for large scale drug discovery applications, there is a high need to develop robust and scalable human cellular models of microglia with reliable translatability to the disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-02-03

    Curcumin protects against cognitive impairments in a rat model of chronic cerebral hypoperfusion combined with diabetes mellitus by suppressing neuroinflammation, apoptosis, and pyroptosis

    ✓ Peer-reviewed TREM2 and immune genetics International immunopharmacology

    Key finding: Chronic cerebral hypoperfusion (CCH) is regarded as a high-risk factor for cognitive decline in vascular dementia (VaD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-02-03

    How many people will need palliative care in Scotland by 2040? A mixed-method study of projected palliative care need and recommendations for service delivery

    ✓ Peer-reviewed Digital health tools BMJ open

    Key finding: By 2040 more people in Scotland are projected to die with palliative care needs, and the complexity of need will increase markedly. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-02-03

    Does the High Prevalence of Vitamin D Deficiency in African Americans Contribute to Health Disparities?

    ✓ Peer-reviewed Disparities Nutrients

    Key finding: We suggest that people with low vitamin D status, which would include most people with dark skin living at high latitudes, along with their health care provider, consider taking vitamin D 3 supplements to raise serum 25-hydroxyvitamin D levels to 30 ng/mL (75 nmol/L) or possibly higher.

    Full summary, score breakdown and related studies → Original source

  7. 2021-02-03

    Blood-brain barrier opening with focused ultrasound in Parkinson's disease dementia

    ✓ Peer-reviewed Caregiving Nature communications

    Key finding: The results are set out in a descriptive manner. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2021-02-02

    Person-Centred Care Transformation in a Nursing Home for Residents with Dementia

    ✓ Peer-reviewed Health systems and care delivery Dementia and geriatric cognitive disorders extra

    Key finding: There were statistically significant improvements in resident well-being (Δ = 0.44, p = 0.029), Positive Engagement Potential (Δ = 0.17, p = 0.002), and Occupational Diversity (Δ = 0.12, p = 0.014) in 2016. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-02-01

    Implementation of Specialist Palliative Care and Outcomes for Hospitalized Patients with Dementia

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: During the study period, 82,118 patients with dementia (mean (SD) age, 83.04 (10.04), 51,170 (62.21%) female) underwent an acute hospitalization, of which 41,227 (50.27%) received care in hospitals that implemented a palliative care program. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-02 month only

    Mangiferin inhibited neuroinflammation through regulating microglial polarization and suppressing NF-κB, NLRP3 pathway

    ✓ Peer-reviewed Inflammation and the immune system Chinese journal of natural medicines

    Key finding: The results showed that mangiferin treatment significantly reduced NO, IL-1β, IL-6 and TNF-α production, also reduced the mRNA and protein of iNOS and COX-2, promoted the polarization of inflammatory toward anti-inflammatory, and inhibited activation of NF-κB and NLRP3 inflammasome. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2021-02-01

    The Impact of Air Pollution on Neurodegenerative Diseases

    ✓ Peer-reviewed Risk factors Therapeutic drug monitoring

    Key finding: PM2.5 can enter the central nervous system through 2 main pathways, the blood-brain barrier and olfactory neurons. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-02 month only

    Alzheimer's disease treatment: The share of herbal medicines

    ✓ Peer-reviewed Treatments Iranian journal of basic medical sciences

    Key finding: Due to the aging of the population and increased prevalence of AD, discovery of new therapeutic agents with the highest effectiveness and fewer side effect seems to be necessary. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2021-02-01

    Characterization of Retinal Microvascular and Choroidal Structural Changes in Parkinson Disease

    ✓ Peer-reviewed Brain scans and imaging JAMA ophthalmology

    Key finding: A total of 124 eyes of 69 participants with PD (39 men [56.5%]; mean [SD] age, 71.7 [7.0] years) and 248 eyes of 137 control participants (77 men [56.2%]; mean [SD] age, 70.9 [6.7] years) were analyzed. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-02-01

    Financial Presentation of Alzheimer Disease and Related Dementias

    ✓ Peer-reviewed Digital health tools JAMA internal medicine

    Key finding: Alzheimer disease and related dementias were associated with adverse financial events years prior to clinical diagnosis that become more prevalent after diagnosis and were most common in lower-education census tracts. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-02-01

    Dysphagia in Older Adults

    ✓ Peer-reviewed Health systems and care delivery Mayo Clinic proceedings

    Key finding: Providers can then request a videofluoroscopic swallow study or a fiberoptic endoscopic evaluation of swallowing for further evaluation of oropharyngeal dysphagia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-02-01

    APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function

    ✓ Peer-reviewed Treatments Science translational medicine

    Key finding: We used 5XFAD mice expressing human APOE4 +/+ (5XE4) that have prominent CAA and parenchymal plaque pathology to assess the efficacy of HAE-4 compared to an Aβ antibody that removes parenchymal Aβ but increases ARIA in humans. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2021-02-01

    Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Brain : a journal of neurology

    Key finding: We found that the presynaptic and postsynaptic markers SNAP25, GAP43 and NRGN are elevated in early Alzheimer's disease i.e. in amyloid-β-positive individuals without evidence of tau pathology. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021-02-01

    Are Chronic Pain Patients with Dementia Being Undermedicated?

    ✓ Peer-reviewed Risk factors Journal of Pain Research

    Key finding: For clinicians and family members, this knowledge gap leads to difficulties in recognizing and assessing chronic pain, which may consequently result in persons with dementia receiving lower levels of pain medication compared to those without cognitive impairment. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2021-02-01

    Differential associations of APOE-ε2 and APOE-ε4 alleles with PET-measured amyloid-β and tau deposition in older individuals without dementia

    ✓ Peer-reviewed Long-term cohort studies European journal of nuclear medicine and molecular imaging

    Key finding: We analyzed data from 462 ADNI participants without dementia who underwent Aβ ([ 18 F]florbetapir or [ 18 F]florbetaben) and tau ([ 18 F]flortaucipir) PET, structural MRI, and cognitive testing. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-02-01

    Natural genetic variation determines microglia heterogeneity in wild-derived mouse models of Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Cell reports

    Key finding: However, single-cell RNA sequencing (scRNA-seq) of microglia in mice, a key preclinical model, has shown mixed results regarding translatability to human studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2021-02-01

    TREM2 sustains macrophage-hepatocyte metabolic coordination in nonalcoholic fatty liver disease and sepsis

    ✓ Peer-reviewed TREM2 and immune genetics The Journal of clinical investigation

    Key finding: Here we identified nonalcoholic fatty liver disease (NAFLD) as an independent risk factor for sepsis in a large clinical cohort and showed a link between mortality in NAFLD-associated sepsis and hepatic mitochondrial and energetic metabolism dysfunction. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021-02-01

    Sex differences and the role of education in cognitive ageing: analysis of two UK-based prospective cohort studies

    ✓ Peer-reviewed Disparities The Lancet. Public health

    Key finding: Our findings suggest that decreasing disparities between sexes in education, due to secular increases in educational opportunities, could attenuate sex differences in dementia risk and cognitive decline in the future.

    Full summary, score breakdown and related studies → Original source

  23. 2021-02-01

    Time course of phosphorylated-tau181 in blood across the Alzheimer's disease spectrum

    ✓ Peer-reviewed Caregiving Brain : a journal of neurology

    Key finding: Smoothing splines demonstrated that earliest plasma p-tau181 changes occurred even before amyloid-β markers reached abnormal levels, with greater rates of change correlating with increased amyloid-β pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2021-02-01

    Sex Differences in Cognitive Decline Among US Adults

    ✓ Peer-reviewed Getting a diagnosis JAMA network open

    Key finding: Among 34 349 participants, 26 088 who self-reported Black or White race, were free of stroke and dementia, and had covariate data at or before the first cognitive assessment were included for analysis. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2021-02-01

    Neuropsychiatric symptoms associated with cerebral small vessel disease: a systematic review and meta-analysis

    ✓ Peer-reviewed Prevention and risk The lancet. Psychiatry

    Key finding: However, some individuals have subtle symptoms associated with acute MRI lesions. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →