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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,676–10,700 of 27,380 studies, newest first · page 428 of 1096.

January 2021 25

  1. 2021-01-09

    Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer's disease models

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neuroinflammation

    Key finding: By engaging membrane-bound TREM2, the selected antibody was shown to promote their cellular proliferation, uptake of oligomeric beta amyloid/apoptotic neurons, and activation in a Syk and Akt dependent manner. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-01-08

    Optical Coherence Tomography in Patients with Alzheimer's Disease: What Can It Tell Us?

    ✓ Peer-reviewed Brain scans and imaging Eye and brain

    Key finding: Seventy-one studies were included for review, representing a total of 6757 patients (2350 AD, 793 MCI, 2902 healthy controls (HC), and 841 others with a range of other neurodegenerative diagnoses). +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-01-08

    Avoidance of Food Waste from a Grocery Retail Store Owner’s Perspective

    ✓ Peer-reviewed Risk factors Sustainability

    Key finding: The results indicated that store owners try to avoid food waste as this incurs a financial loss for them that directly affects them personally, as opposed to store managers of supermarket chains who receive a fixed salary.

    Full summary, score breakdown and related studies → Original source

  4. 2021-01-08

    Association between polygenic risk score of Alzheimer's disease and plasma phosphorylated tau in individuals from the Alzheimer's Disease Neuroimaging Initiative

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's research & therapy

    Key finding: Recent studies suggest that plasma phosphorylated tau181 (p-tau181) is a highly specific biomarker for Alzheimer's disease (AD)-related tau pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-01-08

    Modular machine learning for Alzheimer's disease classification from retinal vasculature

    ✓ Peer-reviewed Digital health tools Scientific reports

    Key finding: The saliency analysis indicated that within retinal images, small vessels carry more information for diagnosing Alzheimer's diseases, which aligns with related studies.

    Full summary, score breakdown and related studies → Original source

  6. 2021-01-08

    6-month consequences of COVID-19 in patients discharged from hospital: a cohort study

    ✓ Peer-reviewed How common it is Lancet (London, England)

    Key finding: After multivariable adjustment, patients showed an odds ratio (OR) 1·61 (95% CI 0·80-3·25) for scale 4 versus scale 3 and 4·60 (1·85-11·48) for scale 5-6 versus scale 3 for diffusion impairment; OR 0·88 (0·66-1·17) for scale 4 versus scale 3 and OR 1·77 (1·05-2·97) for scale 5-6 versus scale 3 for anxiety or depression, and OR 0·74 (0·58-0·96) for scale 4 versus scale 3 and 2·69 (1·46-4·96) for scale 5-6 versus scale 3 for fatigue or muscle weakness. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2021-01-08

    The Association between Vision Impairment and Incidence of Dementia and Cognitive Impairment: A Systematic Review and Meta-analysis

    ✓ Peer-reviewed Prevention and risk Ophthalmology

    Key finding: The global burden of dementia associated with vision impairment then was estimated. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2021-01-08

    Repeated Transcranial Magnetic Stimulation for Improving Cognition in Patients With Alzheimer Disease: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial

    ✓ Peer-reviewed Treatments JMIR research protocols

    Key finding: Recent trials of repetitive transcranial magnetic stimulation (rTMS) have reported encouraging results for improving or stabilizing cognition in patients diagnosed with Alzheimer dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-01-08

    Hippocampal Degeneration and Behavioral Impairment During Alzheimer-Like Pathogenesis Involves Glutamate Excitotoxicity

    ✓ Peer-reviewed Biomarkers Journal of molecular neuroscience : MN

    Key finding: Behavioral characterization in open field and Y-maze revealed that glutamate evoked anxiogenic responses and perturbed spatial memory were inhibited by memantine. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-01-08

    Cognitive Reserve, Alzheimer's Neuropathology, and Risk of Dementia: A Systematic Review and Meta-Analysis

    ✓ Peer-reviewed Prevention and risk Neuropsychology Review

    Key finding: Relevant articles were longitudinal, in English, and investigating MCI or dementia incidence. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2021-01-07

    Imaging of vascular cognitive impairment

    ✓ Peer-reviewed Vascular contributions Clinical imaging

    Key finding: Hemorrhagic dementia results from cerebral amyloid angiopathy and cortical superficial siderosis.

    Full summary, score breakdown and related studies → Original source

  12. 2021-01-07

    Flortaucipir (tau) PET in LGI1 antibody encephalitis

    ✓ Peer-reviewed Brain scans and imaging Annals of clinical and translational neurology

    Key finding: We evaluated whether tau neuropathology measured with [18 F]flortaucipir PET neuroimaging associated with persistent cognitive impairment and hippocampal atrophy in four recovering LGI1 patients (3 men; median age, 67 [37-88] years). +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2021-01-07

    Role of phosphodiesterases in the pathophysiology of neurodevelopmental disorders

    ✓ Peer-reviewed Down syndrome and Alzheimer's Molecular psychiatry

    Key finding: Collectively, these data indicate the potential of PDE modulators to treat neurodevelopmental diseases characterized by learning and memory impairment, alteration of behaviors associated with depression, and deficits in social interaction. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-01-07

    Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation

    ✓ Peer-reviewed Digital health tools Frontiers in neurology

    Key finding: In addition, we classify these PTMs from the perspectives of protein localization, electrostatics, and stability, which all contribute to normal tau function and homeostasis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-01-07

    Cholesterol Metabolism in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets

    ✓ Peer-reviewed Drug development Molecular neurobiology

    Key finding: Brain cholesterol accounts for a large portion of total cholesterol in the human body, and its content must be tightly regulated to ensure normal brain function. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-01-07

    Unhealthy foods may attenuate the beneficial relation of a Mediterranean diet to cognitive decline

    ✓ Peer-reviewed Prevention trials Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: This prospective study found that high consumption of Western diet components attenuates benefits of the MedDiet on cognition.

    Full summary, score breakdown and related studies → Original source

  17. 2021-01-07

    Dystrophic microglia are associated with neurodegenerative disease and not healthy aging in the human brain

    ✓ Peer-reviewed Inflammation and the immune system Neurobiology of aging

    Key finding: Cellular senescence is a hallmark of aging; thus, we hypothesized age could be a cause of dystrophic microglia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021-01-06

    Presenilin 1 mutation likely contributes to U1 small nuclear RNA dysregulation and Alzheimer's disease-like symptoms

    ✓ Peer-reviewed Risk genes beyond APOE Neurobiology of aging

    Key finding: Previous studies showed that U1 small nuclear RNA (snRNA) was selectively enriched in the brain of individuals with familial Alzheimer's disease (AD), resulting in widespread changes in RNA splicing. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2021-01-06

    MIND and Mediterranean Diets Associated with Later Onset of Parkinson's Disease

    ✓ Peer-reviewed Prevention trials Movement disorders : official journal of the Movement Disorder Society

    Key finding: This cross-sectional study found a strong correlation between age of onset of PD and dietary habits, suggesting that nutritional strategies may be an effective tool to delay PD onset. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-01-06

    Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets

    ✓ Peer-reviewed Inflammation and the immune system Science advances

    Key finding: In this study, we interrogate the molecular heterogeneity of AD by analyzing 1543 transcriptomes across five brain regions in two AD cohorts using an integrative network approach. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2021-01-06

    Prevalence of mild cognitive impairment in community-dwelling Chinese populations aged over 55 years: a meta-analysis and systematic review

    ✓ Peer-reviewed Disparities BMC geriatrics

    Key finding: Higher MCI prevalence was identified in community-dwelling older adult populations in China compared with some other countries, possibly due to more broadened criteria being adopted for confirming the diagnosis. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021-01-06

    Multimorbidity burden and dementia risk in older adults: The role of inflammation and genetics

    ✓ Peer-reviewed Prevention and risk Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Individuals with neuropsychiatric, cardiovascular, and sensory impairment/cancer patterns are at increased risk for dementia and APOE ε4, and inflammation may further increase the risk. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021-01-06

    Temporal Dynamics of β-Amyloid Accumulation in Aging and Alzheimer Disease

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Lowering brain Aβ must be accomplished early in the evolution of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2021-01-06

    Validation of the Alzheimer Disease Dementia Conversion-Related Pattern as an ATN Biomarker of Neurodegeneration

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: The mean subject score of the ADCRP was significantly higher in the A+T+ group compared to each of the other group (all p p > 0.1). +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2021-01-05

    Anti-Aβ Antibody Aducanumab Regulates the Proteome of Senile Plaques and Closely Surrounding Tissue in a Transgenic Mouse Model of Alzheimer’s Disease

    ✓ Peer-reviewed Treatments Journal of Alzheimer's Disease

    Key finding: In the aducanumab-treated mice, we identified 17 significantly regulated proteins that were associated with 1) mitochondria and metabolism (ACAT2, ATP5J, ETFA, EXOG, HK1, NDUFA4, NDUFS7, PLCB1, PPP2R4), 2) cytoskeleton and axons (ADD1, CAPZB, DPYSL3, MAG), 3) stress response (HIST1H1C/HIST1H1D, HSPA12A), and 4) AβPP trafficking/processing (CD81, GDI2). +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →