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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 13,201–13,225 of 27,380 studies, newest first · page 529 of 1096.

January 2019 25

  1. 2019-01-26

    Occupational Exposures and Neurodegenerative Diseases-A Systematic Literature Review and Meta-Analyses

    ✓ Peer-reviewed Risk factors International journal of environmental research and public health

    Key finding: Based on 19 studies the weighted RR for occupational exposure to EMFs was 1.26 (95% confidence interval (CI) 1.07⁻1.50) for ALS, 1.33 (95% CI 1.07⁻1.64) for Alzheimer's disease and 1.02 (95% CI 0.83⁻1.26) for Parkinson's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-01-26

    Computerized cognitive training for Chinese mild cognitive impairment patients: A neuropsychological and fMRI study

    ✓ Peer-reviewed Prevention trials NeuroImage. Clinical

    Key finding: Multi-model cognitive training help MCI patients to gained cognition benefit, especially in memory, attention and executive function. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2019-01-25

    Predictions of Alzheimer's disease treatment and care costs in European countries

    ✓ Peer-reviewed Costs and economics PloS one

    Key finding: The results of the simulations show that by prolonging the length of a person's 'stay' in the Mild, Moderate, or Severe stage, the total cost of care for all persons with AD will increase by 2080. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2019-01-25

    Identification of Alzheimer's Disease-Related Genes Based on Data Integration Method

    ✓ Peer-reviewed Genetics Frontiers in genetics

    Key finding: We found several candidate SNPs that have a strong relationship with AD.

    Full summary, score breakdown and related studies → Original source

  5. 2019-01-25

    Emergency Medicine Palliative Care Access (EMPallA): protocol for a multicentre randomised controlled trial comparing the effectiveness of specialty outpatient versus nurse-led telephonic palliative care of older adults with advanced illness

    ✓ Peer-reviewed End-of-life care BMJ open

    Key finding: Emergency department (ED)-initiated palliative care has been shown to improve patient-centred outcomes in older adults with serious, life-limiting illnesses. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2019-01-25

    TREM2 acts as a tumor suppressor in hepatocellular carcinoma by targeting the PI3K/Akt/β-catenin pathway

    ✓ Peer-reviewed TREM2 and immune genetics Oncogenesis

    Key finding: However, TREM2's function in malignant diseases, especially in hepatocellular carcinoma (HCC) remains unknown. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2019-01-25

    Up-Regulation of Trem2 Inhibits Hippocampal Neuronal Apoptosis and Alleviates Oxidative Stress in Epilepsy via the PI3K/Akt Pathway in Mice

    ✓ Peer-reviewed TREM2 and immune genetics Neuroscience bulletin

    Key finding: Functionally, Trem2 (triggering receptor expressed on myeloid cells-2) is an immunoglobulin receptor that affects neurological and psychiatric genetic diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2019-01-25

    Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression

    ✓ Peer-reviewed TREM2 and immune genetics Glia

    Key finding: IFN-I has been implicated in neuroinflammation during neurodegeneration, but its mechanism of induction and its consequences remain unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2019-01-25

    Combining modifiable risk factors and risk of dementia: a systematic review and meta-analysis

    ✓ Peer-reviewed Caregiving BMJ open

    Key finding: The strength of the reported associations, the consistency across studies and the suggestion of a dose response supports a need to keep modifiable risk factor exposure to a minimum and to avoid exposure to additional modifiable risks. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2019-01-24

    Blood-brain barrier permeability and physical exercise

    ✓ Peer-reviewed Prevention trials Journal of neuroinflammation

    Key finding: There is a body of evidence that regular physical exercise diminishes BBB permeability as it reinforces antioxidative capacity, reduces oxidative stress and has anti-inflammatory effects. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2019-01-24

    The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans

    ✓ Peer-reviewed Tau biomarkers Science (New York, N.Y.)

    Key finding: Mouse ISF tau was increased ~90% during normal wakefulness versus sleep and ~100% during SD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2019-01-24

    The Effect of a Comprehensive Dementia Care Management Program on End-of-Life Care

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: Enrollees in a comprehensive dementia care comanagement program had high engagement in advance care planning, high rates of hospice use, and low acute care utilization near the end of life.

    Full summary, score breakdown and related studies → Original source

  13. 2019-01-24

    A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks

    ✓ Peer-reviewed TREM2 and immune genetics Frontiers in neuroscience

    Key finding: Thus, a better understanding of the similarities between the aging process and neurodegenerative diseases at the cellular and molecular level may reveal better understanding of this detrimental relationship. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-01-23

    The ketogenic diet influences taxonomic and functional composition of the gut microbiota in children with severe epilepsy

    ✓ Peer-reviewed Disease mechanisms NPJ biofilms and microbiomes

    Key finding: Here we report that alpha diversity is not changed significantly during the diet, but differences in both taxonomic and functional composition are detected. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-01-23

    Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors

    ✓ Peer-reviewed Inflammation and the immune system Science advances

    Key finding: These data suggest that gingipain inhibitors could be valuable for treating P. gingivalis brain colonization and neurodegeneration in Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  16. 2019-01-23

    Deprescribing benzodiazepines

    ✓ Peer-reviewed Health systems and care delivery The Nurse Practitioner

    Key finding: The mechanism of action of benzodiazepines is through the modulation of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter that suppresses the central nervous system (CNS); the drugs have efficacy for short-term use (less than 1 month), but patients can develop a tolerance and dependence +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2019-01-23

    Type 2 diabetes mellitus, brain atrophy, and cognitive decline

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: In an older cohort with low cerebrovascular disease burden, T2DM contributes to cognitive decline via neurodegeneration. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2019-01-22

    Influence of young adult cognitive ability and additional education on later-life cognition

    ✓ Peer-reviewed Risk factors Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Supporting that idea, age 20 GCA, but not education, was associated with late midlife cortical surface area (n = 367). +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2019-01-22

    Resting state network modularity along the prodromal late onset Alzheimer's disease continuum

    ✓ Peer-reviewed Brain scans and imaging NeuroImage. Clinical

    Key finding: We determined significant differences in FC modular organization with two distinct approaches, network contingency analysis and multiresolution consensus clustering. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2019-01-22

    The validity of dementia diagnoses in routinely collected electronic health records in the United Kingdom: A systematic review

    ✓ Peer-reviewed Digital health tools Pharmacoepidemiology and drug safety

    Key finding: However, the credibility of these estimates is limited by the methodological quality of studies, primarily resulting from insufficient blinding of researchers interpreting the reference test.

    Full summary, score breakdown and related studies → Original source

  21. 2019-01-22

    Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study

    ✓ Peer-reviewed Digital health tools Alzheimer's research & therapy

    Key finding: Differences between predictors for dementia in younger old versus oldest old populations, as well as for dementia versus pathology, should be considered more carefully in future studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2019-01-21

    Astrocyte function from information processing to cognition and cognitive impairment

    ✓ Peer-reviewed Risk factors Nature neuroscience

    Key finding: The roles played by astrocytes are not fully understood, but astrocytes seem to contribute to memory consolidation and seem to mediate the effects of vigilance and arousal on memory performance. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2019-01-21

    The impact of amyloid-beta and tau on prospective cognitive decline in older individuals

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: Our results are consistent with the supposition that both Aβ and tau are necessary for memory decline in the preclinical stages of AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2019-01-21

    Putting patients first: Today's disparities research leading to health equity tomorrow

    ✓ Peer-reviewed Risk factors Health Services Research

    Key finding: Taken together, they move us a little closer toward our goals of achieving health equity. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2019-01-21

    Dementia with Lewy bodies: an update and outlook

    ✓ Peer-reviewed Getting a diagnosis Molecular neurodegeneration

    Key finding: Dementia with Lewy bodies (DLB) is an age-associated neurodegenerative disorder producing progressive cognitive decline that interferes with normal life and daily activities. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →