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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,076–10,100 of 27,380 studies, newest first · page 404 of 1096.

June 2021 25

  1. 2021-06-22

    Obesity, Vascular Disease and Frailty in Aging Women with HIV

    ✓ Peer-reviewed Risk factors Advances in geriatric medicine and research

    Key finding: Women with chronic HIV infection (WWH) living in the United States, experience a disproportionately high rate of obesity compared to uninfected populations. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2021-06-22

    A double-blind randomized controlled trial combining cognitive training (CoRe) and neurostimulation (tDCS) in the early stages of cognitive impairment

    ✓ Peer-reviewed Prevention trials Aging clinical and experimental research

    Key finding: Combined multi-domain interventions may contribute to preventing or delaying disease progression.

    Full summary, score breakdown and related studies → Original source

  3. 2021-06-22

    Characterizing the Clinical Features and Atrophy Patterns of MAPT-Related Frontotemporal Dementia With Disease Progression Modeling

    ✓ Peer-reviewed Digital health tools Neurology

    Key finding: Our results demonstrate that different MAPT mutations give rise to distinct atrophy patterns and clinical phenotype, providing insights into the underlying disease biology and potential utility for patient stratification in therapeutic trials. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-06-21

    Telomere shortening in late-life depression: A potential marker of depression severity

    ✓ Peer-reviewed Risk factors Brain and behavior

    Key finding: TL was significantly shorter in the LLD compared with control participants (p = .039). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-06-21

    The Health & Aging Brain among Latino Elders (HABLE) study methods and participant characteristics

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: The current data provide strong support for continued investigations that examine the risk factors for and biomarkers of AD among diverse populations. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-06-21

    Neurofilament Light Chain as Biomarker for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

    ✓ Peer-reviewed Biomarkers Frontiers in neuroscience

    Key finding: ALS is characterized by degeneration of upper and lower motor neurons causing relentless paralysis of voluntary muscles, whereas in FTD, progressive atrophy of the frontal and temporal lobes of the brain results in deterioration of cognitive functions, language, personality, and behavior. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-06-21

    A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Nature medicine

    Key finding: Both drugs engaged their Aβ targets but neither demonstrated a beneficial effect on cognitive measures compared to controls. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2021-06-21

    Hospital-treated infectious diseases and the risk of dementia: a large, multicohort, observational study with a replication cohort

    ✓ Peer-reviewed Caregiving The Lancet. Infectious diseases

    Key finding: Existing studies have included a narrow range of infectious diseases, relied on short follow-up periods, and provided little evidence for whether the increased risk is limited to specific dementia subtypes or attributable to specific microbes rather than infection burden. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-06-20

    Detecting amyloid positivity in early Alzheimer's disease using combinations of plasma Aβ42/Aβ40 and p-tau

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: A combination of plasma Aβ42/Aβ40 and p-tau217 discriminated Aβ status with relatively high accuracy, whereas p-tau217 showed strongest associations with Aβ pathology in MCI but not in CU.

    Full summary, score breakdown and related studies → Original source

  10. 2021-06-19

    Regulation of Neurotransmitters by the Gut Microbiota and Effects on Cognition in Neurological Disorders

    ✓ Peer-reviewed Disease mechanisms Nutrients

    Key finding: Emerging evidence indicates that gut microbiota is important in the regulation of brain activity and cognitive functions.

    Full summary, score breakdown and related studies → Original source

  11. 2021-06-19

    Cross-sectional and longitudinal associations between adherence to Mediterranean diet with physical performance and cognitive function in older adults: A systematic review and meta-analysis

    ✓ Peer-reviewed Prevention and risk Ageing research reviews

    Key finding: Nineteen cross-sectional studies that investigated 19.734 community-dwelling and institutionalized older adults free of disability and dementia were included. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-06-18

    Evaluation of retinal and choroidal changes in patients with Alzheimer's type dementia using optical coherence tomography angiography

    ✓ Peer-reviewed Brain scans and imaging International journal of ophthalmology

    Key finding: The vessel parameters [P vessel length density=0.005 and P vessel perfusion density=0.006) and average choroid thickness (P<0.001) in the macular area of the ATD group was less than the control group. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2021-06-18

    APP, PSEN1, and PSEN2 Variants in Alzheimer's Disease: Systematic Re-evaluation According to ACMG Guidelines

    ✓ Peer-reviewed Risk genes beyond APOE Frontiers in aging neuroscience

    Key finding: Significant statistically difference was identified among these three genes when comparing the number of pathogenic/likely pathogenic variants (P < 2.2 × 10-16).

    Full summary, score breakdown and related studies → Original source

  14. 2021-06-18

    COVID-19-related neuropathology and microglial activation in elderly with and without dementia

    ✓ Peer-reviewed Clinical safety Brain pathology (Zurich, Switzerland)

    Key finding: Microglial activation in the brainstem was significantly greater in COVID-19 cases (p = 0.046). +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2021-06-18

    The role of diet on the risk of dementia in the oldest old: The Monzino 80-plus population-based study

    ✓ Peer-reviewed Prevention trials Clinical nutrition (Edinburgh, Scotland)

    Key finding: Oldest-old eating less and having diets with less variety and nutrient density were more frequent among subjects with dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-06-18

    Facility-based and home-based multidomain interventions including cognitive training, exercise, diet, vascular risk management, and motivation for older adults: a randomized controlled feasibility trial

    ✓ Peer-reviewed Prevention trials Aging

    Key finding: The RBANS total scale index score improved significantly in the FMI (5.46 ± 7.50, P = 0.004) and HMI (5.50 ± 8.14, P = 0.004) groups compared to the control group (-0.74 ± 11.51).

    Full summary, score breakdown and related studies → Original source

  17. 2021-06-18

    Infiltration by CXCL10 Secreting Macrophages Is Associated With Antitumor Immunity and Response to Therapy in Ovarian Cancer Subtypes

    ✓ Peer-reviewed TREM2 and immune genetics Frontiers in immunology

    Key finding: In this study, high CD3 + T-cells and CD163 + tumor-associated macrophages (TAMs) densities identify a subgroup of immune infiltrated high-grade serous carcinomas (HGSCs) with better outcomes and superior response to platinum-based therapies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021-06-18

    COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1+ neutrophils and CD14+ monocytes

    ✓ Peer-reviewed TREM2 and immune genetics JCI insight

    Key finding: We found that bronchoalveolar lavage fluid (BALF) macrophage clusters FCN1+ and FCN1+SPP1+ predominant in severe COVID-19 were transcriptionally related to synovial tissue macrophage (STM) clusters CD48hiS100A12+ and CD48+SPP1+ that drive rheumatoid arthritis (RA) synovitis. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2021-06-17

    Synaptic Plasticity and Oscillations in Alzheimer's Disease: A Complex Picture of a Multifaceted Disease

    ✓ Peer-reviewed Disease mechanisms Frontiers in molecular neuroscience

    Key finding: In AD, the severity of the cognitive impairment also correlates with the level of disruption of neuronal network dynamics. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-06-17

    Defining end of life in dementia: A systematic review

    ✓ Peer-reviewed End-of-life care Palliative medicine

    Key finding: End-of-life care and research that focuses only on cognitive and functional decline may fail to recognise the complexities and unmet needs relevant to dementia and end of life.

    Full summary, score breakdown and related studies → Original source

  21. 2021-06-17

    Molecular mechanisms underlying nucleotide repeat expansion disorders

    ✓ Peer-reviewed Lewy body dementia Nature reviews. Molecular cell biology

    Key finding: In this Review, we discuss the four major mechanisms by which expansion of short tandem repeats causes disease: loss of function through transcription repression, RNA-mediated gain of function through gelation and sequestration of RNA-binding proteins, gain of function of canonically translated repeat-harbouring proteins, and repeat-associated non-AUG translation of toxic repeat peptides. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021-06-15

    An autopsy case of corticobasal syndrome with pure diffuse Lewy Body Disease

    ✓ Peer-reviewed Brain tissue and pathology Neurocase

    Key finding: Corticobasal syndrome (CBS) is associated with diverse pathological substrates such as tau, prion protein, transactive response and, rarely, alpha synuclein. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021-06-15

    Potential Repositioning of Anti-cancer EGFR Inhibitors in Alzheimer's Disease: Current Perspectives and Challenging Prospects

    ✓ Peer-reviewed Drug development Neuroscience

    Key finding: Clinical trials of new drugs for Alzheimer's disease (AD) have ended with disappointing results, with tremendous resources and time.

    Full summary, score breakdown and related studies → Original source

  24. 2021-06-15

    Automated production of [18F]Flortaucipir for PET imaging of tauopathies

    ✓ Peer-reviewed Brain scans and imaging American journal of nuclear medicine and molecular imaging

    Key finding: The results of QC tests met all the specifications for human use. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2021-06-15

    C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation

    ✓ Peer-reviewed Disease mechanisms Neuron

    Key finding: C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis (ALS)/frontotemporal dementia (FTD) and result in both loss of C9orf72 protein expression and production of potentially toxic RNA and dipeptide repeat proteins. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →