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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 8,201–8,225 of 27,380 studies, newest first · page 329 of 1096.

December 2022 25

  1. 2022-12-08

    Geospatial analysis of patients’ social determinants of health for health systems science and disparity research

    ✓ Peer-reviewed Risk factors International Anesthesiology Clinics

    Key finding: The cross-disciplinary expertise, required for GA, common in the days before medical specialization and enabled by the relative paucity of development in various fields compared with today, can be reborn with the advent of Electronic Health Records (EHR) systems that make the tools of medical geography accessible to a wide variety of health care researchers and clinical subspecialties. +3 more findings

  2. 2022-12-07

    Brain vitamin D forms, cognitive decline, and neuropathology in community-dwelling older adults

    ✓ Peer-reviewed Prevention and risk Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The main form of vitamin D in all brain regions measured was 25(OH)D3 . +4 more findings

  3. 2022-12-07

    Metformin: new applications for an old drug

    ✓ Peer-reviewed Drug development Journal of basic and clinical physiology and pharmacology

    Key finding: Concerning renal function, studies showed that daily oral administration of metformin could ameliorate kidney fibrosis and normalize kidney structure and function.

  4. 2022-12-07

    Quantification of [18 F]florbetaben amyloid-PET imaging in a mixed memory clinic population: The ABIDE project

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: CL was associated with syndromic (F = 4.42, p = 0.014) and etiological diagnosis (F = -12.66, p < 0.001), with Alzheimer's disease (AD) patients showing the highest amyloid burden (62.9 ± 27.5), followed by dementia with Lewy bodies (DLB) (25.3 ± 35.5) and cardiovascular disease (CVD) (16.7 ± 24.5), and finally frontotemporal lobe degeneration (FTLD) (5.0 ± 17.22, t = -12.66, p < 0.001). +3 more findings

  5. 2022-12-07
  6. 2022-12-07
  7. 2022-12-07
  8. 2022-12-07

    Platinum-Based TREM2 Inhibitor Suppresses Tumors by Remodeling the Immunosuppressive Microenvironment

    ✓ Peer-reviewed TREM2 and immune genetics Angewandte Chemie (International ed. in English)

    Key finding: A platinum(IV) complex OPA derived from oxaliplatin (OP) and artesunate (ART) exhibited direct cytotoxicity against human colon cancer cells and immunomodulatory activity to inhibit TREM2 on macrophages in vitro and vivo. +2 more findings

  9. 2022-12-06
  10. 2022-12-05

    Racial/ethnic disparities in dementia incidence, outcomes, and health-care utilization

    ✓ Peer-reviewed Disparities Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Disparities in incidence of NDD between Black and White beneficiaries narrowed by 0.37 per 100 person-years from 2014 to 2017. +4 more findings

  11. 2022-12-05

    MRI-Visible Perivascular Spaces and Risk of Incident Dementia: The Framingham Heart Study

    ✓ Peer-reviewed Long-term cohort studies Neurology

    Key finding: Perivascular spaces (PVS) visible on MRI scans may represent key aspects in the pathophysiology of stroke and dementia, including cerebral small vessel disease and glymphatic dysfunction. +3 more findings

  12. 2022-12-05

    The cost of inaction on physical inactivity to public health-care systems: a population-attributable fraction analysis

    ✓ Peer-reviewed Caregiving The Lancet. Global health

    Key finding: 499·2 million new cases of preventable major NCDs would occur globally by 2030 if the prevalence of physical inactivity does not change, with direct health-care costs of INT$520 billion.

  13. 2022-12-05

    Association of Data-Driven White Matter Hyperintensity Spatial Signatures With Distinct Cerebral Small Vessel Disease Etiologies

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Data-driven WMH spatial patterns reflect discrete underlying etiologies including arteriolosclerosis, CAA, AD, and normal aging. +3 more findings

  14. 2022-12-04

    TDP-43 pathology effect on volume and flortaucipir uptake in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Older participants had lower hippocampal volumes and overall flortaucipir uptake. +4 more findings

  15. 2022-12-04

    Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits

    ✓ Peer-reviewed Genetics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Mutation screening revealed a novel probably pathogenic mutation (PSEN1 p.Leu232Phe). +2 more findings

  16. 2022-12-03

    Is plasma amyloid-β 1-42/1-40 a better biomarker for Alzheimer's disease than AβX-42/X-40?

    ✓ Peer-reviewed Biomarkers Fluids and barriers of the CNS

    Key finding: The median Aβ1-42/1-40 ratio was 20.86% lower in amyloid-positive subjects than in the amyloid-negative group, while the median AβX-42/X-40 ratio was only 15.56% lower. +4 more findings

  17. 2022-12-03

    TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neuroinflammation

    Key finding: Neuroinflammation is one of the most important processes in secondary injury after traumatic brain injury (TBI). +3 more findings

  18. 2022-12-02
  19. 2022-12-02

    Amyloid β-Peptide Causes the Permanent Activation of CaMKIIα through Its Oxidation

    ✓ Peer-reviewed Disease mechanisms International journal of molecular sciences

    Key finding: We found that oAβ produce reactive oxygen species (ROS), that induce CaMKIIα oxidation in human neuroblastoma cells as we assayed by western blot and immunofluorescence. +4 more findings

  20. 2022-12-02

    Effects of Kami Guibi-tang in patients with mild cognitive impairment: study protocol for a phase III, randomized, double-blind, and placebo-controlled trial

    ✓ Peer-reviewed Clinical trials BMC complementary medicine and therapies

    Key finding: This study aims to provide confirmatory evidence of the effect of the Korean herbal medicine, KGT, on improving cognitive function in patients with aMCI. +2 more findings

  21. 2022-12-02

    Alternative role of glucagon-like Peptide-1 receptor agonists in neurodegenerative diseases

    ✓ Peer-reviewed Drug development European journal of pharmacology

    Key finding: Limited options are available for the treatment of age-related, multiple pathogenic mechanism-contributed diseases that usually advance to irreversible conditions with severe neurological deficits and result in a heavy socioeconomic burden on patients, families, and society.

  22. 2022-12-02

    Comparing ARIA-E severity scales and effects of treatment management thresholds

    ✓ Peer-reviewed Treatments Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: SSAE-3/5 scores correlated with BGTS scores, with high inter-reader intraclass correlation coefficients across all scales. +2 more findings

  23. 2022-12 month only

    Usability and acceptability of wearable technology in the early detection of dementia

    ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Sixteen semi-structured interviews were conducted with nine participants, at two-time points. +4 more findings

  24. 2022-12-01

    Plasma neurofilament light chain in memory clinic practice: Evidence from a real-life study

    ✓ Peer-reviewed Biomarkers Neurobiology of disease

    Key finding: (N = 558, mean age = 69.2 ± 8.8, 56.5% women) were diagnosed with AD (n = 274, considering dementia and MCI stages), frontotemporal dementia (FTD, n = 55), Lewy body disease (LBD, n = 40, considering MCI and dementia stages), other neurodegenerative diseases, n = 57 (e.g Supranuclear Palsy, Corticobasal syndrome), non-neurodegenerative cognitive impairment (NND, n = 79, e.g. vascular lesions, epilepsy or psychiatric disorders) or subjective cognitive impairment (SCI, n = 53). +3 more findings

  25. 2022-12-01

    Spatial proteomics in three-dimensional intact specimens

    ✓ Peer-reviewed Digital health tools Cell

    Key finding: Here, we present DISCO-MS, a technology that combines whole-organ/whole-organism clearing and imaging, deep-learning-based image analysis, robotic tissue extraction, and ultra-high-sensitivity mass spectrometry. +4 more findings

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