alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,451–10,475 of 27,380 studies, newest first · page 419 of 1096.

March 2021 25

  1. 2021-03-04

    Cuba's cardiovascular risk factors: International comparison of levels and education gradients

    ✓ Peer-reviewed Risk factors PloS one

    Key finding: Neither medically amenable nor behavioral risk factors are uniformly better in Cuba than comparison countries. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-03-04

    Comparison of CSF neurofilament light chain, neurogranin, and tau to MRI markers

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Higher CSF NfL was associated with decreasing microstructural integrity and WMH. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-03-04

    CSF sTREM2 is elevated in a subset in GRN-related frontotemporal dementia

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: Excessive microglial activation might be a central pathological process in GRN-related frontotemporal dementia (FTD-GRN). +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-03-04

    Excess mortality for care home residents during the first 23 weeks of the COVID-19 pandemic in England: a national cohort study

    ✓ Peer-reviewed Health systems and care delivery BMC Medicine

    Key finding: Up to 7 August 2020, there were 29,542 (95% CI 25,176 to 33,908) excess deaths in all care homes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-03-04

    Astrocytes in Alzheimer's Disease: Pathological Significance and Molecular Pathways

    ✓ Peer-reviewed Inflammation and the immune system Cells

    Key finding: Recent data provide compelling evidence that distinct astrocyte states are associated with specific stages of Alzheimer´s disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-03-04

    African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants

    ✓ Peer-reviewed Tau biomarkers Neurology. Genetics

    Key finding: The primary cohort included 91 AAs and 868 NHWs. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-03-04

    Rural-urban differences in diagnostic incidence and prevalence of Alzheimer's disease and related dementias

    ✓ Peer-reviewed Disparities Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: These data suggest that older adults in rural communities may be underdiagnosed with ADRD, and/or diagnosed at later stages of dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2021-03-04

    Onset of Preclinical Alzheimer Disease in Monozygotic Twins

    ✓ Peer-reviewed Biomarkers Annals of neurology

    Key finding: Twenty-seven individuals (14%) had an abnormal amyloid PET, and 14 twin-pairs (15%) showed discordant amyloid PET scans. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2021-03-03

    Gamma subunit of complement component 8 is a neuroinflammation inhibitor

    ✓ Peer-reviewed Inflammation and the immune system Brain : a journal of neurology

    Key finding: However, in this study, we revealed an inhibitory role of complement component 8 gamma (C8G) in neuroinflammation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-03-03

    Systematic identification of risk factors and drug repurposing options for Alzheimer's disease

    ✓ Peer-reviewed Drug development Alzheimer's & dementia (New York, N. Y.)

    Key finding: There was strong evidence of a causal association between glioma risk, reduced trunk fat-free mass, lower education levels, lower intelligence and a higher risk of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2021-03-03

    The application of optical coherence tomography angiography in Alzheimer's disease: A systematic review

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Fourteen studies assessing OCT-A in preclinical Alzheimer's disease (AD), mild cognitive impairment, or AD were included. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-03-03

    ADAM10: Biomarker of mild cognitive impairment but not of cognitive frailty

    ✓ Peer-reviewed Biomarkers Experimental gerontology

    Key finding: Mild cognitive impairment (MCI) associated with physical frailty gave rise to the new concept of cognitive frailty. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2021-03-02

    Marital loss and risk of dementia: Do race and gender matter?

    ✓ Peer-reviewed Disparities Social science & medicine (1982)

    Key finding: Recent studies have found that marital loss through divorce or widowhood is associated with a higher risk of dementia for older adults. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-03-02

    ROSE: A Retinal OCT-Angiography Vessel Segmentation Dataset and New Model

    ✓ Peer-reviewed Digital health tools IEEE transactions on medical imaging

    Key finding: The experimental results demonstrate that our OCTA-Net yields better vessel segmentation performance in OCTA than both traditional and other deep learning methods. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2021-03-02

    Referral criteria to specialist palliative care for patients with dementia: A systematic review

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: This systematic review highlighted the lack of consensus regarding referral criteria for palliative care in patients with dementia and the need to identify timely triggers to standardize referral. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2021-03-02

    Triad of TDP43 control in neurodegeneration: autoregulation, localization and aggregation

    ✓ Peer-reviewed Brain tissue and pathology Nature reviews. Neuroscience

    Key finding: TDP43 typically resides in the nucleus but can shuttle between the nucleus and the cytoplasm to exert its multiple functions, which include regulation of the splicing, trafficking and stabilization of RNA. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2021-03-02

    Alzheimer's disease

    ✓ Peer-reviewed Prevention and risk Lancet (London, England)

    Key finding: The most recent data indicate that, by 2050, the prevalence of dementia will double in Europe and triple worldwide, and that estimate is 3 times higher when based on a biological (rather than clinical) definition of Alzheimer's disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2021-03-01

    Prevalence of Central Nervous System-Active Polypharmacy Among Older Adults With Dementia in the US

    ✓ Peer-reviewed Digital health tools JAMA

    Key finding: Gabapentin was the most common medication and was associated with 33.0% of polypharmacy-days. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2021-03-01

    Prevalence of Concurrent Functional Vision and Hearing Impairment and Association With Dementia in Community-Dwelling Medicare Beneficiaries

    ✓ Peer-reviewed Risk factors JAMA network open

    Key finding: In this cohort study of US Medicare beneficiaries, dual sensory impairment was prevalent in older adults and associated with increased risk of dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-03-01

    Hearing and dementia: from ears to brain

    ✓ Peer-reviewed Risk factors Brain : a journal of neurology

    Key finding: The association between hearing impairment and dementia has emerged as a major public health challenge, with significant opportunities for earlier diagnosis, treatment and prevention.

    Full summary, score breakdown and related studies → Original source

  21. 2021-03-01

    New insights into atypical Alzheimer's disease in the era of biomarkers

    ✓ Peer-reviewed Risk genes beyond APOE The Lancet. Neurology

    Key finding: Research into atypical Alzheimer's disease has revealed previously unrecognised neuropathological heterogeneity across the Alzheimer's disease spectrum.

    Full summary, score breakdown and related studies → Original source

  22. 2021-03-01

    Population-based blood screening for preclinical Alzheimer's disease in a British birth cohort at age 70

    ✓ Peer-reviewed Biomarkers Brain : a journal of neurology

    Key finding: Mass spectrometry plasma measures performed significantly better than any other measure (amyloid-β1-42/1-40: 0.817; 0.770-0.864 and amyloid-β composite: 0.820; 0.775-0.866). +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2021-03-01

    CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Brain : a journal of neurology

    Key finding: Insoluble tau aggregates composed of the microtubule binding region (MTBR) of tau are highly associated with the cognitive and clinical symptoms of Alzheimer's disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2021-03-01

    Cerebral small vessel disease: A review

    ✓ Peer-reviewed Vascular contributions Advances in clinical and experimental medicine : official organ Wroclaw Medical University

    Key finding: The disease is characterized by a diverse clinical and radiological picture. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2021-03-01

    Comparison of Palliative Care Delivery in the Last Year of Life Between Adults With Terminal Noncancer Illness or Cancer

    ✓ Peer-reviewed End-of-life care JAMA network open

    Key finding: A lower proportion of patients with cancer had palliative care initiated in the home (16 088 [14.5%]) compared with patients with chronic organ failure (6904 [32.8%]; absolute difference, -18.3%) or dementia (3922 [27.9%]; absolute difference, -13.4%). +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →