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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 20,351–20,375 of 27,380 studies, newest first · page 815 of 1096.

January 2011 25

  1. 2011-01-01

    Elderly-onset essential tremor and mild cognitive impairment: a population-based study (NEDICES)

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: Frontal-executive dysfunction, memory impairments, and dementia have been associated with essential tremor (ET). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2011-01-01

    Statins as neuroprotectants: a comparative in vitro study of lipophilicity, blood-brain-barrier penetration, lowering of brain cholesterol, and decrease of neuron cell death

    ✓ Peer-reviewed Drug development Journal of Alzheimer's disease : JAD

    Key finding: Our results indicate that monacolin J derivatives (natural and semi-synthetic statins) are the best candidates for the prevention of neurodegenerative conditions due to their higher potential BBB penetration capacity, cholesterol lowering effect on neurons with a satisfactory safety profile, and in vitro protection against cell death caused by okadaic acid in culture.

    Full summary, score breakdown and related studies → Original source

  3. 2011-01-01

    Age-related macular degeneration (AMD): Alzheimer's disease in the eye?

    ✓ Peer-reviewed Brain scans and imaging Journal of Alzheimer's disease : JAD

    Key finding: In both diseases, the detrimental intra- and extracellular deposits have many similarities. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2011-01-01

    Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Recent evidence suggests that microtubule-associated protein tau may mediate amyloid-β peptide (Aβ) toxicity by modulating the tyrosine kinase Fyn. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2011-01-01

    Amyloid precursor protein processing and Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE Annual review of neuroscience

    Key finding: Genetic, biochemical, and behavioral research suggest that physiologic generation of the neurotoxic Aβ peptide from sequential amyloid precursor protein (APP) proteolysis is the crucial step in the development of AD.

    Full summary, score breakdown and related studies → Original source

  6. 2011-01-01

    Episodic memory decline predicts cortical amyloid status in community-dwelling older adults

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: Of 195 who completed 24-month evaluation (age 51 to 80 years), 15 memory decliners (mean age 62.7 years, SD 7.6) were identified, and matched with 33 non-decliners (mean age 63.3 years, SD 8.2). +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2011-01-01

    A novel blood test for the early detection of Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Assuming a clinical accuracy of 80%, calculations indicate that the agreement with underlying true pathology is in the range 85%-90%. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2011-01-01

    GLT-1 loss accelerates cognitive deficit onset in an Alzheimer's disease animal model

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: GLT-1, the dominant glutamate transporter in the cerebral cortex and hippocampus, is significantly reduced in Alzheimer's disease (AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2011-01-01

    Vitamin C restores behavioral deficits and amyloid-β oligomerization without affecting plaque formation in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: The decline of the antioxidant status is associated with dementia in AD patients, especially low levels of vitamin C. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2011-01-01

    PKC ε activation prevents synaptic loss, Aβ elevation, and cognitive deficits in Alzheimer's disease transgenic mice

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: These results suggest that synaptic loss and the resulting cognitive deficits depend on the balance between the lowering effects of Aβ on PKC α and ε versus the lowering effects of PKC on Aβ in AD transgenic mice.

    Full summary, score breakdown and related studies → Original source

  11. 2011 no date recorded — placed by publication year

    Associations between cognitive, functional, and FDG-PET measures of decline in AD and MCI

    ✓ Peer-reviewed Brain scans and imaging Neurobiology of Aging

    Key finding: Low glucose metabolism at baseline predicted subsequent ADAS-cog and FAQ decline. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2011-01-01

    Physicians in Supporting Roles in Chronic Disease Care: The CareMore Model

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: In most of these nonacademic healthcare delivery systems, traditional randomized clinical trial designs to evaluate effectiveness are too rigid, too expensive, and take too long to achieve results. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2011-01-01

    Wayfinding for People with Dementia: A Review of the Role of Architectural Design

    ✓ Peer-reviewed Health systems and care delivery HERD Health Environments Research & Design Journal

    Key finding: The design of the physical environment plays a major role in supporting the wayfinding abilities of people with dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2011-01-01

    Invisibility

    ✓ Peer-reviewed Risk factors New England review

    Key finding: But when I imagined the short, awkward conversations that would have been likely to ensue, conversations whose power to irk me would almost certainly be out of all proportion to their length, I always made the same swift choice: leave it. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2011-01-01

    Disturbed choline plasmalogen and phospholipid fatty acid concentrations in Alzheimer's disease prefrontal cortex

    ✓ Peer-reviewed Inflammation and the immune system Journal of Alzheimer's disease : JAD

    Key finding: Lipid concentration changes have been reported in different brain regions, but often partially or as a percent of the total concentration. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2011-01-01

    Operationalizing diagnostic criteria for Alzheimer's disease and other age-related cognitive impairment-Part 2

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Experience and insights are discussed by investigators from the Framingham Heart Study, the East Boston Senior Health Project, the Chicago Health and Aging Project, the Mayo Clinic Study of Aging, the Baltimore Longitudinal Study of Aging, and the Aging, Demographics, and Memory Study. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2011-01-01

    Treatment with cholinesterase inhibitors and memantine of patients in the Alzheimer's Disease Neuroimaging Initiative

    ✓ Peer-reviewed Treatments Archives of neurology

    Key finding: The 59 recruiting sites for the Alzheimer's Disease Neuroimaging Initiative (ADNI). +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2011-01-01

    A randomized controlled trial of high-dose vitamin D2 followed by intranasal insulin in Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: Nasal insulin acutely improves cognition and vitamin D upregulates insulin receptor expression and enhances insulin action. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2011-01-01

    Plasma sphingomyelins are associated with cognitive progression in Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: In this study we sought to determine whether plasma ceramides, dihydroceramides (DHCer), sphingomyelins (SM), or dihydrosphingomyelin (DHSM) levels and ratios of SM/ceramide or DHSM/DHCer were predictive of progression in AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2011-01-01

    [The role of CSF markers in the early diagnosis of Alzheimer's disease]

    ✓ Peer-reviewed Tau biomarkers Tijdschrift voor psychiatrie

    Key finding: Biomarkers in cerebrospinal fluid (CSF) are being used increasingly to diagnose early Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2011-01-01

    Cerebrospinal fluid profiles and prospective course and outcome in patients with amnestic mild cognitive impairment

    ✓ Peer-reviewed Tau biomarkers Archives of neurology

    Key finding: Total tau (T-tau), tau phosphorylated at threonine 181, and β-amyloid 1-42 peptide (Aβ42) were immunoassayed in CSF samples obtained from patients with MCI enrolled in the Alzheimer's Disease Neuroimaging Initiative. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2011-01-01

    Salivary tau species are potential biomarkers of Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Increased phosphorylated tau and total tau levels, combined with reduced concentrations of amyloid-β 1-42 (Aβ42) in cerebrospinal fluid (CSF), but not in plasma or serum, have been generally accepted as sensitive AD diagnostic markers. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2011-01-01

    Meta-analysis of the association between variants in SORL1 and Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Archives of neurology

    Key finding: Comprehensive and unbiased meta-analysis of all published and unpublished data from case-control studies for the SORL1 single-nucleotide polymorphisms (SNPs) that had been repeatedly assessed across studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2011-01-01

    Disease tracking markers for Alzheimer's disease at the prodromal (MCI) stage

    ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD

    Key finding: Current evidence suggests that biochemical, neuroimaging, electrophysiological, and neuropsychological markers can track the disease over time since the MCI stage (also called prodromal AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2011-01-01

    Maintenance treatment of depression in old age: a randomized, double-blind, placebo-controlled evaluation of the efficacy and safety of donepezil combined with antidepressant pharmacotherapy

    ✓ Peer-reviewed Mild cognitive impairment Archives of general psychiatry

    Key finding: Donepezil and antidepressant therapy temporarily improved global cognition (treatment × time interaction, F₂,₂₁₆ = 3.78; P = .03), but effect sizes were small (Cohen d = 0.27, group difference at 1 year). +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →