Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 20,326–20,350 of 27,380 studies, newest first · page 814 of 1096.
January 2011 25
-
2011-01-18
Olfaction and color vision identify impending neurodegeneration in rapid eye movement sleep behavior disorder
66/100 ✓ Peer-reviewed Brain scans and imaging Annals of neurology
Key finding: Olfaction and color vision identify early-stage synuclein-mediated neurodegenerative diseases. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-18
Association of lung function with cognitive decline and dementia: the Atherosclerosis Risk in Communities (ARIC) Study
54/100 ✓ Peer-reviewed Long-term cohort studies European journal of neurology
Key finding: However, many did not adjust for important confounders or did not include women and non-whites. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-18
Left anterior temporal cortex actively engages in speech perception: A direct cortical stimulation study
40/100 ✓ Peer-reviewed Digital health tools Neuropsychologia
Key finding: Separate from the posterior temporal language area, electrical cortical stimulation revealed a well-restricted language area in the anterior part of the superior temporal sulcus and gyrus (aSTS/STG) in both patients. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-17
Gait stability and variability measures show effects of impaired cognition and dual tasking in frail people
40/100 ✓ Peer-reviewed Clinical safety Journal of neuroengineering and rehabilitation
Key finding: The observed trunk adaptations were a consistent instability factor. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-14
Statins, risk of dementia, and cognitive function: secondary analysis of the ginkgo evaluation of memory study
65/100 ✓ Peer-reviewed Cognitive tests and assessment Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Key finding: Lipid-lowering medications (LLMs) and especially statin drugs can delay cognitive decline and dementia onset in individuals with and without mild cognitive impairment (MCI) at baseline. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-13
Early 11C-PIB frames and 18F-FDG PET measures are comparable: a study validated in a cohort of AD and FTLD patients
45/100 ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Key finding: A 7-min window, corresponding to minutes 1-8 (frames 5-15), produced the highest voxelwise correlation between (18)F-FDG and pPIB (R = 0.78 ± 0.05). +3 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-12
Neuroprotective properties of GLP-1: theoretical and practical applications
36/100 ✓ Peer-reviewed Drug development Current medical research and opinion
Key finding: The increased risk of Alzheimer's disease, Parkinson's disease and stroke in people with type 2 diabetes suggests that shared mechanisms/pathways of cell death, possibly related to insulin dysregulation, may underlie all of these disorders. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2011-01-12
Multimodal classification of Alzheimer's disease and mild cognitive impairment
40/100 ✓ Peer-reviewed Tau biomarkers NeuroImage
Key finding: However, most existing research focuses on only a single modality of biomarkers for diagnosis of AD and MCI, although recent studies have shown that different biomarkers may provide complementary information for the diagnosis of AD and MCI. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-12
Palliative assessment and advance care planning in severe dementia: an exploratory randomized controlled trial of a complex intervention
71/100 ✓ Peer-reviewed End-of-life care Palliative medicine
Key finding: The 32 patient participants were physically frail and in the advanced stages of dementia: 62% had pressure damage to the skin, all needed feeding assistance and 95% were in pain. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-12
Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease
57/100 ✓ Peer-reviewed Mild cognitive impairment PloS one
Key finding: These six markers describe six clinicopathological stages from cognitive normalcy to mild dementia, including stages defined by increased risk of cognitive decline.
Full summary, score breakdown and related studies → Original source
-
2011-01-12
Sleep and sleep disorders in older adults
47/100 ✓ Peer-reviewed Risk factors Neuropsychology review
Key finding: A common but significant change associated with aging is a profound disruption to the daily sleep-wake cycle. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-12
Default mode network connectivity in stable vs progressive mild cognitive impairment
65/100 ✓ Peer-reviewed Brain scans and imaging Neurology
Key finding: GOF indices were highest in normal controls, intermediate in MCI, and lowest in AD (p Conclusions fMRI connectivity indices distinguish patients with MCI who undergo cognitive decline and conversion to AD from those who remain stable over a 2- to 3-year follow-up period. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-10
Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain
36/100 ✓ Peer-reviewed Drug development Journal of neuroscience research
Key finding: We found that, in all three mouse models, progenitor cell division was enhanced compared with nondiabetic controls after chronic i.p. injection of either liraglutide or exendin-4 by 100-150% (P < 0.001). +1 more finding
Full summary, score breakdown and related studies → Original source
-
2011-01-10
Medicare expenditures among nursing home residents with advanced dementia
48/100 ✓ Peer-reviewed End-of-life care Archives of internal medicine
Key finding: Medicare expenditures among nursing home residents with advanced dementia vary substantially. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-10
Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels
51/100 ✓ Peer-reviewed Genetics Archives of neurology
Key finding: The association of rs1990622 with AAO explains, in part, the wide range in the AAO of disease among GRN mutation carriers. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-08
A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people
59/100 ✓ Peer-reviewed Treatments Clinical nutrition (Edinburgh, Scotland)
Key finding: Homocysteine lowering in dementia patients did not significantly reduce global cognitive decline. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-07
APP processing in Alzheimer's disease
40/100 ✓ Peer-reviewed Risk genes beyond APOE Molecular brain
Key finding: Aβ is generated from β-amyloid precursor protein (APP) through sequential cleavages first by β-secretase and then by γ-secretase complex. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-07
Regulator of calcineurin 1 (RCAN1) facilitates neuronal apoptosis through caspase-3 activation
45/100 ✓ Peer-reviewed Down syndrome and Alzheimer's The Journal of biological chemistry
Key finding: Furthermore, we found that the neurotoxicity of RCAN1-1 is inhibited by knock-out of caspase-3 in caspase-3(-/-) neurons.
Full summary, score breakdown and related studies → Original source
-
2011-01-06
Cohort Profile: The Longitudinal Aging Study Amsterdam
66/100 ✓ Peer-reviewed Risk factors International Journal of Epidemiology
Key finding: As shown in Table 2, attrition in LASA is associated with predictors and outcomes of interest to our research. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-06
Microinfarct pathology, dementia, and cognitive systems
36/100 ✓ Peer-reviewed Long-term cohort studies Stroke
Key finding: Microinfarcts are common, and persons with multiple cortical microinfarcts have higher odds of dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-05
Presence of reactive microglia and neuroinflammatory mediators in a case of frontotemporal dementia with P301S mutation
41/100 ✓ Peer-reviewed Disease mechanisms Neuro-degenerative diseases
Key finding: Our findings suggest that microglial activation and the production of proinflammatory mediators by phospho-tau-positive neurons and glial cells may differentially contribute to neuronal death and disease progression in neurodegenerative tauopathies. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-04
Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice
52/100 ✓ Peer-reviewed Lewy body dementia The Journal of clinical investigation
Key finding: TDP-43 is normally localized in the nucleus with roles in the regulation of gene expression, and pathological cytoplasmic aggregates are associated with depletion of nuclear protein. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2011 year only
Apolipoprotein E expression and purification
38/100 ✓ Peer-reviewed Genetics Methods in molecular biology (Clifton, N.J.)
Key finding: We also review the considerations that are critical for obtaining reliable and interpretable results with the end product.
Full summary, score breakdown and related studies → Original source
-
2011-01-01
Huntington's disease: from molecular pathogenesis to clinical treatment
40/100 ✓ Peer-reviewed Mild cognitive impairment The Lancet. Neurology
Key finding: Huntington's disease has served as a model for the study of other more common neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2011-01-01
Biomonitoring and biomarkers of organophosphate pesticides exposure - state of the art
36/100 ✓ Peer-reviewed Risk factors Annals of agricultural and environmental medicine : AAEM
Key finding: A particularly high risk of exposure to hazardous chemicals is associated with the use of pesticides in agriculture, especially the use of organophosphorous pesticides (OP), which are the most widely and commonly used insecticides worldwide. +2 more findings
Full summary, score breakdown and related studies → Original source
Browse the library by subject, with the full score breakdown →