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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,101–19,125 of 27,380 studies, newest first · page 765 of 1096.

November 2012 25

  1. 2012-11-07

    Persistent cognitive impairment, hippocampal atrophy and EEG changes in sepsis survivors

    ✓ Peer-reviewed Hippocampus size on brain scans Journal of neurology, neurosurgery, and psychiatry

    Key finding: This study demonstrates permanent cognitive impairment in several domains in both septic and non-septic ICU survivors and unspecific brain dysfunction. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2012-11-07

    A direct morphometric comparison of five labeling protocols for multi-atlas driven automatic segmentation of the hippocampus in Alzheimer's disease

    ✓ Peer-reviewed Long-term cohort studies NeuroImage

    Key finding: Unfortunately, morphological heterogeneity in AD can prevent accurate demarcation of the hippocampus. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2012-11-07

    Recurrent mutations in DNAJC5 cause autosomal dominant Kufs disease

    ✓ Peer-reviewed Digital health tools Clinical genetics

    Key finding: The leucine residues at positions 115 and 116 are hotspots for mutations and result in a homogeneous phenotype of progressive myoclonus epilepsy with onset around 30 years old.

    Full summary, score breakdown and related studies → Original source

  4. 2012-11-06

    State-dependent changes in hippocampal grey matter in depression

    ✓ Peer-reviewed Hippocampus size on brain scans Molecular psychiatry

    Key finding: Neuroplasticity following antidepressant drug treatment in the hippocampus has been demonstrated in animal models but adaptive changes after such treatment have not been shown in humans. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2012-11-06

    Altered concentrations of amyloid precursor protein metabolites in the cerebrospinal fluid of patients with bipolar disorder

    ✓ Peer-reviewed Tau biomarkers Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    Key finding: Progressive cognitive dysfunction such as impairments in executive function and verbal memory is common in euthymic bipolar patients. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2012-11-06

    Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study

    ✓ Peer-reviewed Prevention and risk The Lancet. Neurology

    Key finding: These findings contribute to the understanding of preclinical familial Alzheimer's disease and help set the stage for assessment of amyloid-modifying treatments in the prevention of familial Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  7. 2012-11-06

    Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study

    ✓ Peer-reviewed Prevention and risk The Lancet. Neurology

    Key finding: 44 participants were included: 20 PSEN1 E280A mutation carriers and 24 non-carriers. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2012-11-06

    Differential regulation of amyloid-β endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms

    ✓ Peer-reviewed Genetics The Journal of biological chemistry

    Key finding: Overexpression of Rab5 or Rab7, small GTPases that function in vesicle fusion for early and late endosomes, respectively, significantly accelerates Aβ endocytic trafficking to the lysosomes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2012-11-05

    Subsyndromal delirium in older people: a systematic review of frequency, risk factors, course and outcomes

    ✓ Peer-reviewed Clinical safety International journal of geriatric psychiatry

    Key finding: SSD in older people may be a frequent and clinically important condition that falls on a continuum between no symptoms and full delirium. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2012-11-05

    Preferences for end-of-life care: a nominal group study of people with dementia and their family carers

    ✓ Peer-reviewed Caregiving Palliative medicine

    Key finding: Wishes and preferences of people with dementia and their family carers may differ. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2012-11-02

    British Association of Dermatologists’ guidelines for the management of bullous pemphigoid 2012

    ✓ Peer-reviewed Drug development British Journal of Dermatology

    Key finding: The overall objective of the guideline is to provide up‐to‐date, evidence‐based recommendations for the management of bullous pemphigoid (BP). +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2012-11-02

    Communication skills training in dementia care: a systematic review of effectiveness, training content, and didactic methods in different care settings

    ✓ Peer-reviewed Health systems and care delivery International psychogeriatrics

    Key finding: This review shows that communication skills training in dementia care significantly improves the quality of life and wellbeing of people with dementia and increases positive interactions in various care settings. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2012-11-01

    Drug repositioning for Alzheimer's disease

    ✓ Peer-reviewed Drug development Nature reviews. Drug discovery

    Key finding: Indeed, a substantial body of preclinical work indicates that several classes of such drugs have potentially beneficial effects on Alzheimer's-like brain pathology, and for some drugs the evidence is also supported by epidemiological data or preliminary clinical trials.

    Full summary, score breakdown and related studies → Original source

  14. 2012-11-01

    Region-specific hierarchy between atrophy, hypometabolism, and β-amyloid (Aβ) load in Alzheimer's disease dementia

    ✓ Peer-reviewed Brain scans and imaging The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Significant differences in the levels of atrophy, hypometabolism, and Aβ deposition were found in most brain areas, but the hierarchy differed across regions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2012-11-01

    Gating of fear in prelimbic cortex by hippocampal and amygdala inputs

    ✓ Peer-reviewed Hippocampus size on brain scans Neuron

    Key finding: These results suggest a prefrontal circuit whereby hippocampus gates amygdala-based fear.

    Full summary, score breakdown and related studies → Original source

  16. 2012-11-01

    The effects of cognitive speed of processing training among older adults with psychometrically- defined mild cognitive impairment

    ✓ Peer-reviewed Prevention trials Current Alzheimer research

    Key finding: There were no significant changes in performance across time, indicating initial training gains were maintained. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2012-11-01

    Soluble aβ promotes wild-type tau pathology in vivo

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Growing evidence suggests that soluble Aβ species can drive Alzheimer disease (AD) pathogenesis by inducing a cascade of events including tau hyperphosphorylation, proteasome impairment, and synaptic dysfunction.

    Full summary, score breakdown and related studies → Original source

  18. 2012-11-01

    Monoacylglycerol lipase is a therapeutic target for Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Cell reports

    Key finding: There are no effective medications currently available to prevent and treat AD and halt disease progression. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2012-11-01

    Measuring Alzheimer disease progression with transition probabilities: estimates from NACC-UDS

    ✓ Peer-reviewed Long-term cohort studies Current Alzheimer research

    Key finding: Estimate the probabilities, for Alzheimer's disease (AD) patients, of transitioning between stages of disease severity (mild, moderate, severe, dead) and care settings (community, institutional). +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2012-11-01

    The link between the GBA gene and parkinsonism

    ✓ Peer-reviewed Lewy body dementia The Lancet. Neurology

    Key finding: Subsequently, findings from large studies showed that patients with Parkinson's disease and associated Lewy body disorders had an increased frequency of GBA mutations when compared with control individuals.

    Full summary, score breakdown and related studies → Original source

  21. 2012-11-01

    Assessment scales in dementia

    ✓ Peer-reviewed Caregiving Therapeutic advances in neurological disorders

    Key finding: Assessment scales in the domains of cognition, function, behaviour, quality of life, depression in dementia, carer burden and overall dementia severity are reviewed in this article.

    Full summary, score breakdown and related studies → Original source

  22. 2012-11-01

    Nonpharmacologic management of behavioral symptoms in dementia

    ✓ Peer-reviewed Caregiving JAMA

    Key finding: If untreated, these behaviors can accelerate disease progression, worsen functional decline and quality of life, cause significant caregiver distress, and result in earlier nursing home placement. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2012-11-01

    Physical activity prevents progression for cognitive impairment and vascular dementia: results from the LADIS (Leukoaraiosis and Disability) study

    ✓ Peer-reviewed Brain scans and imaging Stroke

    Key finding: Physical activity reduces the risk of cognitive impairment, mainly vascular dementia, in older people living independently.

    Full summary, score breakdown and related studies → Original source

  24. 2012-11-01

    Effects of growth hormone–releasing hormone on cognitive function in adults with mild cognitive impairment and healthy older adults: results of a controlled trial

    ✓ Peer-reviewed Treatments Archives of neurology

    Key finding: The intent-to-treat analysis indicated a favorable effect of GHRH on cognition (P=.03), which was comparable in adults with MCI and healthy older adults.

    Full summary, score breakdown and related studies → Original source

  25. 2012-11-01

    Effect of lifestyle activities on Alzheimer disease biomarkers and cognition

    ✓ Peer-reviewed Genetics Annals of neurology

    Key finding: None of the lifestyle variables were correlated with the biomarkers, and the path associations between lifestyle variables and biomarkers were not significant (p > 0.05). +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →