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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,726–19,750 of 27,380 studies, newest first · page 790 of 1096.

January 2012 25

  1. 2012-01-01

    Cerebrospinal fluid levels of β-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia

    ✓ Peer-reviewed Tau biomarkers Archives of general psychiatry

    Key finding: Early detection of prodromal Alzheimer disease (AD) is important because new disease-modifying therapies are most likely to be effective when initiated during the early stages of disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2012-01-01

    The French series of autosomal dominant early onset Alzheimer's disease cases: mutation spectrum and cerebrospinal fluid biomarkers

    ✓ Peer-reviewed Risk genes beyond APOE Journal of Alzheimer's disease : JAD

    Key finding: In 33 additional families (23% of the series), the genetic determinism remained uncharacterized after this screening. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2012-01-01

    Proteomic changes in cerebrospinal fluid of presymptomatic and affected persons carrying familial Alzheimer disease mutations

    ✓ Peer-reviewed Risk genes beyond APOE Archives of neurology

    Key finding: We compared proteomic profiles of CSF from individuals with FAD who were mutation carriers (MCs) and related noncarriers (NCs). +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2012-01-01

    Late-life depression as a risk factor for mild cognitive impairment or Alzheimer's disease in 30 US Alzheimer's disease centers

    ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD

    Key finding: At baseline, depressed subjects performed significantly worse on cognitive tests. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2012-01-01

    Fornix integrity and hippocampal volume predict memory decline and progression to Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Fornix FA both cross-sectionally correlated with and longitudinally predicted memory decline and progression to AD.

    Full summary, score breakdown and related studies → Original source

  6. 2012-01-01

    National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

    ✓ Peer-reviewed Lewy body dementia Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: A consensus panel from the United States and Europe was convened recently to update and revise the 1997 consensus guidelines for the neuropathologic evaluation of Alzheimer's disease (AD) and other diseases of brain that are common in the elderly. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2012-01-01

    Genetic analysis of Down syndrome facilitated by mouse chromosome engineering

    ✓ Peer-reviewed Down syndrome and Alzheimer's Bioengineered bugs

    Key finding: Because these phenotypes are associated with an extra copy of a human chromosome, the genetic analysis of Down syndrome has been a major challenge. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2012-01-01

    Discoveries in Down syndrome: moving basic science to clinical care

    ✓ Peer-reviewed Down syndrome and Alzheimer's Progress in brain research

    Key finding: In conclusion, a number of therapeutic strategies have been defined that may restore cognitive function in mouse models of DS.

    Full summary, score breakdown and related studies → Original source

  9. 2012-01-01

    Therapeutic approaches in the improvement of cognitive performance in Down syndrome: past, present, and future

    ✓ Peer-reviewed Down syndrome and Alzheimer's Progress in brain research

    Key finding: Unfortunately, results from clinical trials do not support the use of NMDA antagonists like memantine and we should await at the development of safer GABA(A) antagonists to conclude about the efficacy of approaching Down syndrome therapeutics by modulating neurotransmission systems altered in this pathology.

    Full summary, score breakdown and related studies → Original source

  10. 2012-01-01

    Oxidative stress and mitochondrial dysfunction in Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Advances in experimental medicine and biology

    Key finding: Another well documented hallmark of DS phenotype is represented by a set of immunologic defects encompassing a number of B and T-cell functions and cytokine production, together prompting a proinflammatory state. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2012-01-01

    Patient-related risk factors for postoperative mortality and periprosthetic joint infection in medicare patients undergoing TKA

    ✓ Peer-reviewed Risk factors Clinical orthopaedics and related research

    Key finding: We believe this information important when counseling elderly patients regarding the risks of mortality and PJI after TKA and risk-adjusting publicly reported TKA patient outcomes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2012-01-01

    Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease

    ✓ Peer-reviewed Risk factors Current Alzheimer research

    Key finding: Other factors, including impairments in energy metabolism, increased oxidative stress, inflammation, insulin and IGF resistance, and insulin/IGF deficiency in the brain should be incorporated into all equations used to develop diagnostic and therapeutic approaches to AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2012-01-01

    The economic cost of brain disorders in Europe

    ✓ Peer-reviewed How common it is European journal of neurology

    Key finding: Our cost model revealed that brain disorders overall are much more costly than previously estimated constituting a major health economic challenge for Europe. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2012-01-01

    Hypertension prevalence, awareness, treatment and control among older people in Latin America, India and China: a 10/66 cross-sectional population-based survey

    ✓ Peer-reviewed Disparities Journal of hypertension

    Key finding: Hypertension prevalence was higher in urban (range 52.6-79.8%) than rural sites (range 42.6-56.9%), and lower in men than women [pooled prevalence ratio 0.89, 95% confidence interval (CI) 0.85-0.93]. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2012-01-01

    Advanced dementia: state of the art and priorities for the next decade

    ✓ Peer-reviewed Disparities Annals of internal medicine

    Key finding: Research over the past 25 years has largely focused on describing the experience of patients with advanced dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2012-01-01

    Mild cognitive impairment: disparity of incidence and prevalence estimates

    ✓ Peer-reviewed Caregiving Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Prevalence and incidence estimates associated with MCI vary greatly both between definitions and within a definition across the 42 publications. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2012-01-01

    Caregiving burden, stress, and health effects among family caregivers of adult cancer patients

    ✓ Peer-reviewed Caregiving JAMA

    Key finding: This report describes a case that exemplifies caregiving burden and discusses the importance of identifying caregivers at risk of negative health outcomes and intervening to attenuate the stress associated with the caregiving experience.

    Full summary, score breakdown and related studies → Original source

  18. 2012-01-01

    2012 Alzheimer's disease facts and figures

    ✓ Peer-reviewed Caregiving Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Over the coming decades, the aging of the baby boom generation is projected to result in an additional 10 million people with AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2012-01-01

    Memory after silent stroke: hippocampus and infarcts both matter

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Both hippocampal volume and brain infarcts independently contribute to memory performance in elderly individuals without dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2012-01-01

    Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: Increased (11)C-DED binding throughout the brain of the MCI (11)C-PIB+ patients potentially suggests that astrocytosis is an early phenomenon in AD development. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2012-01-01

    Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Sub-cellular biochemistry

    Key finding: The neurotoxic potential of the Aβ peptide results from its biochemical properties that favor aggregation into insoluble oligomers and protofibrils. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2012-01-01

    Hippocampal atrophy and ventricular enlargement in normal aging, mild cognitive impairment (MCI), and Alzheimer Disease

    ✓ Peer-reviewed Getting a diagnosis Alzheimer disease and associated disorders

    Key finding: Hippocampal atrophy and ventricular enlargement have been associated with AD but also with normal aging. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2012-01-01

    Association of incident dementia with hospitalizations

    ✓ Peer-reviewed Getting a diagnosis JAMA

    Key finding: Four hundred ninety-four individuals eventually developed dementia and 427 (86%) of these persons were admitted at least once; 2525 remained free of dementia and 1478 (59%) of those were admitted at least once. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2012-01-01

    Contributions of brain insulin resistance and deficiency in amyloid-related neurodegeneration in Alzheimer's disease

    ✓ Peer-reviewed Prevention and risk Drugs

    Key finding: Growing evidence supports the concept that AD is fundamentally a metabolic disease that results in progressive impairment in the brain's capacity to utilize glucose and respond to insulin and insulin-like growth factor (IGF) stimulation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2012-01-01

    Changes in brain volume and cognition in a randomized trial of exercise and social interaction in a community-based sample of non-demented Chinese elders

    ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD

    Key finding: Compared to the No Intervention group, significant increases in brain volume were seen in the Tai Chi and Social Intervention groups (p < 0.05). +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →