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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 22,776–22,800 of 27,380 studies, newest first · page 912 of 1096.

January 2007 25

  1. 2007-01-18

    Essential role of the microglial triggering receptor expressed on myeloid cells-2 (TREM2) for central nervous tissue immune homeostasis

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neuroimmunology

    Key finding: Recently, it was shown that loss-of-function mutations of the innate microglial immune receptor triggering receptor expressed on myeloid cells-2 (TREM2) led to a chronic neurodegenerative disease, named Nasu-Hakola disease or polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2007-01-18

    Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases

    ✓ Peer-reviewed Mild cognitive impairment Brain research reviews

    Key finding: Chronic cerebral hypoperfusion has been associated with cognitive decline in aging and Alzheimer's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2007-01-18

    Mitochondrial dysfunction and molecular pathways of disease

    ✓ Peer-reviewed Risk factors Experimental and molecular pathology

    Key finding: Since the first mitochondrial dysfunction was described in the 1960s, the medicine has advanced in its understanding the role mitochondria play in health, disease, and aging. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2007-01-16

    Effects of TC-1734 (AZD3480), a selective neuronal nicotinic receptor agonist, on cognitive performance and the EEG of young healthy male volunteers

    ✓ Peer-reviewed Cognitive tests and assessment Psychopharmacology

    Key finding: These early data in healthy subjects provide encouragement to consider development of AZD3480 as a novel agent for the treatment of cognitive decline in the elderly, including age-associated memory impairment and/or dementia of the Alzheimer's type. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2007-01-14

    The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Nature genetics

    Key finding: We report here that inherited variants in the SORL1 neuronal sorting receptor are associated with late-onset Alzheimer disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2007-01-13

    Relevance of donepezil in enhancing learning and memory in special populations: a review of the literature

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of autism and developmental disorders

    Key finding: This review discusses the laboratory and clinical research supporting the rationale for the efficacy of donepezil (Aricept USA) in enhancing cognition in autism, Alzheimer disease, Down syndrome, traumatic brain injury, Attention Deficit Hyperactivity Disorder (ADHD), and schizophrenia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2007-01-12

    Ubiquitinated pathological lesions in frontotemporal lobar degeneration contain the TAR DNA-binding protein, TDP-43

    ✓ Peer-reviewed Brain tissue and pathology Acta neuropathologica

    Key finding: We confirm that TDP-43 protein is a component of the UBQ immunoreactive (UBQ-ir) neuronal cytoplasmic inclusions (NCI), neuronal intranuclear inclusions (NII) and neurites of the cerebral cortex and hippocampus in FTLD-U. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2007-01-11

    Hippocampal hypometabolism predicts cognitive decline from normal aging

    ✓ Peer-reviewed Getting a diagnosis Neurobiology of aging

    Key finding: Hippocampal MRglc reductions using FDG-PET during normal aging predict cognitive decline years in advance of the clinical diagnosis. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2007-01-09

    Alzheimer neurofibrillary degeneration: significance, etiopathogenesis, therapeutics and prevention

    ✓ Peer-reviewed Tau biomarkers Journal of cellular and molecular medicine

    Key finding: Independent of the aetiology, this disease is characterized clinically by chronic and progressive dementia and histopathologically by neurofibrillary degeneration of abnormally hyperphosphorylated tau seen as intraneuronal neurofibrillary tangles, neuropil threads and dystrophic neurites, and by neuritic (senile) plaques of beta-amyloid. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2007-01-08

    Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults

    ✓ Peer-reviewed Brain scans and imaging Archives of neurology

    Key finding: The very mildest symptomatic stage of AD exhibits the same CSF biomarker phenotype as more advanced AD.

    Full summary, score breakdown and related studies → Original source

  11. 2007-01-01

    Prediction of Alzheimer’s Disease Using the CSF Aβ42/Aβ40 Ratio in Patients with Mild Cognitive Impairment

    ✓ Peer-reviewed Biomarkers Dementia and Geriatric Cognitive Disorders

    Key finding: CSF Abeta42 concentration at baseline and the Abeta42/Abeta40 ratio were significantly decreased in the MCI patients who developed AD as compared to cognitively stable MCI patients and MCI patients who developed other forms of dementia (p < 0.001). +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2007 year only

    Rivastigmine in the treatment of Alzheimer's disease: an update

    ✓ Peer-reviewed Treatments Clinical interventions in aging

    Key finding: Although no cure has yet been discovered for Alzheimer's disease, symptomatic therapies are now widely available and offer significant relief to patients and benefits to caregivers in terms of reduced care burden.

    Full summary, score breakdown and related studies → Original source

  13. 2007 year only

    Is long-term treatment of Alzheimer's disease with cholinesterase inhibitor therapy justified?

    ✓ Peer-reviewed Treatments Drugs & aging

    Key finding: Nevertheless, the results of virtually all open-label extensions of the pivotal trials, studies of patients with AD at different levels of severity and clinical trials using other designs favour treatment over no treatment for periods of up to 5 years. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2007-01-01

    How common are the "common" neurologic disorders?

    ✓ Peer-reviewed How common it is Neurology

    Key finding: Using the best available data, our survey of a limited number of disorders shows that the burden of neurologic illness affects many millions of people in the United States.

    Full summary, score breakdown and related studies → Original source

  15. 2007-01-01

    Psychiatric and behavioral disorders in persons with Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Mental retardation and developmental disabilities research reviews

    Key finding: Similar to the state of the broader intellectual disabilities field, many gaps exist in the research and treatment of mental health concerns in people with Down syndrome. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2007-01-01

    Alzheimer's disease in Down syndrome: neurobiology and risk

    ✓ Peer-reviewed Down syndrome and Alzheimer's Mental retardation and developmental disabilities research reviews

    Key finding: Down syndrome (DS) is characterized by increased mortality rates, both during early and later stages of life, and age-specific mortality risk remains higher in adults with DS compared with the overall population of people with mental retardation and with typically developing populations. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2007-01-01

    Hydrogen sulfide (H2S) - the third gas of interest for pharmacologists

    ✓ Peer-reviewed Down syndrome and Alzheimer's Pharmacological reports : PR

    Key finding: Recent studies suggest that hydrogen sulfide (H(2)S) is the third gaseous mediator in mammals. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2007-01-01

    Walking while talking: effect of task prioritization in the elderly

    ✓ Peer-reviewed Digital health tools Archives of physical medicine and rehabilitation

    Key finding: Changing instructions while maintaining the same cognitive and motor tasks on WWT in older adults result in task prioritization effects. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2007-01-01

    Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Using highly differentiated cultures of hippocampal neurons, a preferred model for studies of synapse cell biology, we found that ADDLs bound to neurons with specificity, attaching to presumed excitatory pyramidal neurons but not GABAergic neurons. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2007-01-01

    Anti-inflammatory drugs in the 21st century

    ✓ Peer-reviewed Disease mechanisms Sub-cellular biochemistry

    Key finding: The discovery of the COX isoforms led to establishing their importance in many non-arthritic or non-pain states where there is an inflammatory component to pathogenesis, including cancer, Alzheimer's and other neurodegenerative diseases. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2007-01-01

    Current analytical methods for the detection of dityrosine, a biomarker of oxidative stress, in biological samples

    ✓ Peer-reviewed Risk factors Mass spectrometry reviews

    Key finding: Dityrosine is a fluorescent molecule formed as a result of normal posttranslational processing. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2007-01-01

    Pediatric respiratory and systemic effects of chronic air pollution exposure: nose, lung, heart, and brain pathology

    ✓ Peer-reviewed Risk factors Toxicologic pathology

    Key finding: Exposures to particulate matter and gaseous air pollutants have been associated with respiratory tract inflammation, disruption of the nasal respiratory and olfactory barriers, systemic inflammation, production of mediators of inflammation capable of reaching the brain and systemic circulation of particulate matter. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2007-01-01

    Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder?

    ✓ Peer-reviewed Risk factors International review of neurobiology

    Key finding: Microglial activation similar to that which occurs in peripheral macrophages during inflammatory attack was first demonstrated in the Alzheimer's disease (AD) brain two decades ago. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2007-01-01

    Curcumin: the Indian solid gold

    ✓ Peer-reviewed Risk factors Advances in experimental medicine and biology

    Key finding: Extensive research within the last half century has proven that most of these activities, once associated with turmeric, are due to curcumin.

    Full summary, score breakdown and related studies → Original source

  25. 2007-01-01

    Glycogen synthase kinase-3 inhibition is integral to long-term potentiation

    ✓ Peer-reviewed Drug development The European journal of neuroscience

    Key finding: These results suggest that the inhibition of GSK-3 facilitates the induction of LTP and this might explain some of the negative effects of GSK-3 on learning and memory.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →