Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 20,151–20,175 of 27,380 studies, newest first · page 807 of 1096.

May 2011 1

  1. 2011-05-01

    Clinical features and APOE genotype of pathologically proven early-onset Alzheimer disease

    ✓ Peer-reviewed Genetics Neurology

    Key finding: One third of patients with pathologic confirmed EOAD presented with atypical symptoms. +2 more findings

April 2011 24

  1. 2011-04-30

    Inflammation induced by infection potentiates tau pathological features in transgenic mice

    ✓ Peer-reviewed Drug development The American journal of pathology

    Key finding: Researchers have recently demonstrated that triggering inflammation in the brain exacerbates tau pathological characteristics in animal models. +4 more findings

  2. 2011-04-29

    Hippocampal volume reduction in first-episode and chronic schizophrenia: a review and meta-analysis

    ✓ Peer-reviewed Hippocampus size on brain scans The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry

    Key finding: Several magnetic resonance imaging studies have reported hippocampal volume reduction in patients with schizophrenia, but other studies have reported contrasting results. +1 more finding

  3. 2011-04-29

    Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease

    ⚠ Retracted — do not rely on it Lewy body dementia PloS one

    Key finding: Dementia with Lewy bodies (DLB) and Parkinson's Disease (PD) are common causes of motor and cognitive deficits and are associated with the abnormal accumulation of alpha-synuclein (α-syn). +3 more findings

    Scored 32 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

  4. 2011-04-27

    CSF biomarkers in posterior cortical atrophy

    ✓ Peer-reviewed Tau biomarkers Neurology

    Key finding: This prospective observational study included 22 patients with PCA who underwent CSF biomarker analysis of total tau (t-tau), phosphorylated tau on amino acid 181 (p-tau181), and amyloid β (Aβ(42)). +3 more findings

  5. 2011-04-27

    Resting bold fMRI differentiates dementia with Lewy bodies vs Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Changes in functional connectivity in DLB indicate patterns of activation that are distinct from those seen in AD and may improve discrimination of DLB from AD and cognitively normal individuals. +2 more findings

  6. 2011-04-26

    A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases

    ✓ Peer-reviewed Risk factors Journal of pineal research

    Key finding: Approaches to better understand molecular details behind the rhythmic signalling in the human pineal gland are limited but implicitly warranted, as human chronobiological dysfunctions are often associated with alterations in melatonin synthesis. +2 more findings

  7. 2011-04-26

    APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP

    ✓ Peer-reviewed Risk genes beyond APOE The EMBO journal

    Key finding: Previously, we generated APPsα knock-in (KI) mice expressing solely the secreted ectodomain APPsα. +3 more findings

  8. 2011-04-26

    Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS

    ✓ Peer-reviewed Lewy body dementia PLoS biology

    Key finding: Our findings suggest that TDP-43 and FUS, though similar RNA-binding proteins, aggregate and confer disease phenotypes via distinct mechanisms.

  9. 2011-04-24

    Alzheimer's disease is not "brain aging": neuropathological, genetic, and epidemiological human studies

    ✓ Peer-reviewed Risk factors Acta neuropathologica

    Key finding: In conclusion, it may be most fruitful to focus attention on specific pathways involved in AD rather than attributing it to an inevitable consequence of aging.

  10. 2011-04-22

    The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer s & Dementia

    Key finding: The National Institute on Aging and the Alzheimer's Association charged a workgroup with the task of developing criteria for the symptomatic predementia phase of Alzheimer's disease (AD), referred to in this article as mild cognitive impairment due to AD. +4 more findings

  11. 2011-04-21

    Study of Mental Activity and Regular Training (SMART) in at risk individuals: a randomised double blind, sham controlled, longitudinal trial

    ✓ Peer-reviewed Prevention trials BMC geriatrics

    Key finding: SMART will provide a novel evaluation of the immediate and long term benefits of CT, PRT, and combined CT and PRT on global cognitive function and brain morphology, as well as potential underlying mechanisms of adaptation in older adults at risk of further cognitive decline. +4 more findings

  12. 2011-04-21
  13. 2011-04-21

    Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: This long "preclinical" phase of AD would provide a critical opportunity for therapeutic intervention; however, we need to further elucidate the link between the pathological cascade of AD and the emergence of clinical symptoms. +4 more findings

  14. 2011-04-21

    The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: On the basis of the past 27 years of experience, we made several changes in the clinical criteria for the diagnosis. +4 more findings

  15. 2011-04-20

    Solanezumab for Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Expert opinion on biological therapy

    Key finding: Alzheimer's disease (AD) is a debilitating neurodegenerative illness affecting over 35 million people worldwide.

  16. 2011-04-20

    Population Surveillance of Dementia Mortality

    ✓ Peer-reviewed Risk factors International Journal of Environmental Research and Public Health

    Key finding: Use of specific (G30, F01) versus non-specific diagnoses (F02, R54) varied among states and over time, explaining most of the temporal increase in rate of Alzheimer's disease. +1 more finding

  17. 2011-04-19

    Intra-individual variability in Alzheimer's disease and cognitive aging: definitions, context, and effect sizes

    ✓ Peer-reviewed Long-term cohort studies PloS one

    Key finding: Sample statistics were computed from ADNI cohorts with no cognitive diagnosis, a diagnosis of mild cognitive impairment (MCI), and a diagnosis of possible or probable Alzheimer's disease (AD). +3 more findings

  18. 2011-04-19

    Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis

    ✓ Peer-reviewed Digital health tools PloS one

    Key finding: Using a targeted proteomic screen, we identified novel candidate biomarkers that complement the best current CSF biomarkers for distinguishing very mildly/mildly demented from cognitively normal individuals. +4 more findings

  19. 2011-04-18

    Assessment of acetylcholinesterase activity using indoxylacetate and comparison with the standard Ellman's method

    ✓ Peer-reviewed Risk factors International journal of molecular sciences

    Key finding: Moreover, the results were compared to the standard Ellman's method.

  20. 2011-04-17

    Effect of interventions to reduce potentially inappropriate use of drugs in nursing homes: a systematic review of randomised controlled trials

    ✓ Peer-reviewed Clinical safety BMC geriatrics

    Key finding: Interventions using educational outreach, on-site education given alone or as part of an intervention package and pharmacist medication review may under certain circumstances reduce inappropriate drug use, but the evidence is of low quality. +1 more finding

  21. 2011-04-16

    Hypothesis for the pathophysiology of delirium: role of baseline brain network connectivity and changes in inhibitory tone

    ✓ Peer-reviewed Clinical safety Medical hypotheses

    Key finding: The pathogenesis of this cognitive disintegration is unclear; herein a hypothesis is proposed that delirium results from an acute breakdown in network connectivity within the brain.

  22. 2011-04-16

    Oxysterols as biomarkers in neurodegenerative diseases

    ✓ Peer-reviewed Genetics Chemistry and physics of lipids

    Key finding: In conclusion the analysis of oxysterols in plasma and CSF seems to contribute to investigate the role of cholesterol metabolism in pathogenesis of neurodegeneration and is helpful in the study of patients affected by neurodegenerative diseases.

  23. 2011-04-14

    Predictive value of APOE-ε4 allele for progression from MCI to AD-type dementia: a meta-analysis

    ✓ Peer-reviewed Mild cognitive impairment Journal of neurology, neurosurgery, and psychiatry

    Key finding: The APOE-ε4 allele is associated with a moderately increased risk for progression from MCI to AD-type dementia. +3 more findings

  24. 2011-04-14

    Cognitive status correlates with white matter alteration in Parkinson's disease

    ✓ Peer-reviewed Mild cognitive impairment Human brain mapping

    Key finding: Fractional anisotropy (FA) map of a patient group was compared with that of control subjects by using tract-based spatial statistics. +4 more findings

Browse the library by subject, with the full score breakdown →