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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 20,401–20,425 of 27,380 studies, newest first · page 817 of 1096.

December 2010 25

  1. 2010-12-22

    Development of a new predictive model for polypathological patients. The PROFUND index

    ✓ Peer-reviewed Clinical safety European journal of internal medicine

    Key finding: This prognostic index provides an accurate and transportable method of stratifying 1-year death risk in PP. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2010-12-22

    Adherence to a Mediterranean-type dietary pattern and cognitive decline in a community population

    ✓ Peer-reviewed Prevention trials The American journal of clinical nutrition

    Key finding: The Mediterranean dietary pattern as captured by the MedDiet scoring system may reduce the rate of cognitive decline with older age. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2010-12-22

    Nasu-Hakola disease with a splicing mutation of TREM2 in a Japanese family

    ✓ Peer-reviewed TREM2 and immune genetics European journal of neurology

    Key finding: Nasu-Hakola disease (NHD) is a rare autosomal recessive disorder, characterized by a combination of progressive presenile dementia and formation of multifocal bone cysts, caused by genetic mutations of DAP12 and TREM2, which constitute a receptor/adapter signaling complex expressed on osteoclasts, dendritic cells, macrophages, and microglia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2010-12-22

    The Danish Alzheimer intervention study: rationale, study design and baseline characteristics of the cohort

    ✓ Peer-reviewed Treatments Neuroepidemiology

    Key finding: The study will explore the added value of a multifaceted intervention programme and contribute to the design of future interventions for patients with mild dementia and their caregivers.

    Full summary, score breakdown and related studies → Original source

  5. 2010-12-21

    DTI measures in crossing-fibre areas: increased diffusion anisotropy reveals early white matter alteration in MCI and mild Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging NeuroImage

    Key finding: Significant differences between MCI and AD were essentially confined to the corpus callosum. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2010-12-20

    TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor

    ✓ Peer-reviewed Lewy body dementia Molecular and cellular biology

    Key finding: Recent work also suggests that TDP-43 associates with cytoplasmic stress granules, which are transient structures that form in response to stress. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2010-12-20

    Huntington's disease: a clinical review

    ✓ Peer-reviewed Getting a diagnosis Orphanet journal of rare diseases

    Key finding: The progression of the disease leads to a complete dependency in daily life, which results in patients requiring full-time care, and finally death.

    Full summary, score breakdown and related studies → Original source

  8. 2010-12-16

    Role of iron in brain injury after intraventricular hemorrhage

    ✓ Peer-reviewed Hippocampus size on brain scans Stroke

    Key finding: Iron has a role in brain injury after IVH. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2010-12-15

    The pathological process underlying Alzheimer's disease in individuals under thirty

    ✓ Peer-reviewed Down syndrome and Alzheimer's Acta neuropathologica

    Key finding: Brains of 42 individuals between the ages of 4 and 29 were examined with antibodies (AT8, 4G8) and silver stains for the presence of intraneuronal and extracellular protein aggregates associated with Alzheimer's disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2010-12-15

    Socially assistive robots in elderly care: a systematic review into effects and effectiveness

    ✓ Peer-reviewed Digital health tools Journal of the American Medical Directors Association

    Key finding: The positive results described, however, prompt further effectiveness research in this field.

    Full summary, score breakdown and related studies → Original source

  11. 2010-12-14

    Abeta42 neurotoxicity is mediated by ongoing nucleated polymerization process rather than by discrete Abeta42 species

    ✓ Peer-reviewed Treatments The Journal of biological chemistry

    Key finding: We observed that crude Aβ42 preparations, containing a monomeric and heterogeneous mixture of Aβ42 oligomers, were more toxic than purified monomeric, protofibrillar fractions, or fibrils. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2010-12-14

    Loss of white matter integrity is associated with gait disorders in cerebral small vessel disease

    ✓ Peer-reviewed Vascular contributions Brain : a journal of neurology

    Key finding: Pathological studies have demonstrated abnormalities in white matter that may appear normal on brain imaging. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2010-12-13

    The role of DYRK1A in neurodegenerative diseases

    ✓ Peer-reviewed Down syndrome and Alzheimer's The FEBS journal

    Key finding: Recent studies indicate that the dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) gene, which is located on chromosome 21q22.2 and is overexpressed in Down syndrome (DS), may play a significant role in developmental brain defects and in early onset neurodegeneration, neuronal loss and dementia in DS. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2010-12-12

    Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Nature neuroscience

    Key finding: We found a non-apoptotic baseline caspase-3 activity in hippocampal dendritic spines and an enhancement of this activity at the onset of memory decline in the Tg2576-APPswe mouse model of Alzheimer's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2010-12-10

    Predictive markers for AD in a multi-modality framework: an analysis of MCI progression in the ADNI population

    ✓ Peer-reviewed Mild cognitive impairment NeuroImage

    Key finding: Alzheimer's Disease (AD) and other neurodegenerative diseases affect over 20 million people worldwide, and this number is projected to significantly increase in the coming decades. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2010-12-10

    Childhood adversity heightens the impact of later-life caregiving stress on telomere length and inflammation

    ✓ Peer-reviewed Risk factors Psychosomatic medicine

    Key finding: Adverse childhood events are related to continued vulnerability among older adults, enhancing the impact of chronic stressors. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2010-12-10

    Behavioural-variant frontotemporal dementia: diagnosis, clinical staging, and management

    ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology

    Key finding: Recently, criteria proposed for bvFTD define three levels of diagnostic certainty: possible, probable, and definite. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2010-12-09

    Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease

    ✓ Peer-reviewed Disease mechanisms Science

    Alzheimer's disease is hypothesized to be caused by an imbalance between β-amyloid (Aβ) production and clearance that leads to Aβ accumulation in the central nervous system (CNS).

    Full summary, score breakdown and related studies → Original source

  19. 2010-12-09

    The cholinergic system in aging and neuronal degeneration

    ✓ Peer-reviewed Mild cognitive impairment Behavioural brain research

    Key finding: However, the previous view of significant cholinergic cell loss during aging has been challenged. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2010-12-09

    Interim follow-up of a randomized controlled trial comparing Chinese style mind body (Tai Chi) and stretching exercises on cognitive function in subjects at risk of progressive cognitive decline

    ✓ Peer-reviewed Prevention and risk International journal of geriatric psychiatry

    Key finding: We reported the interim findings of a randomized controlled trial (RCT) to examine the effects of a mind body physical exercise (Tai Chi) on cognitive function in Chinese subjects at risk of cognitive decline.

    Full summary, score breakdown and related studies → Original source

  21. 2010-12-07

    Cerebrospinal fluid tau, p-tau 181 and amyloid-β38/40/42 in frontotemporal dementias and primary progressive aphasias

    ✓ Peer-reviewed Tau biomarkers Dementia and geriatric cognitive disorders

    Key finding: High CSF p-tau and low ratios of Aβ(1-42)/Aβ(1-40) and Aβ(1-42)/Aβ(1-38), respectively, were specific for AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2010-12-03

    TDP-43 regulates its mRNA levels through a negative feedback loop

    ✓ Peer-reviewed Lewy body dementia The EMBO journal

    Key finding: Our analysis indicated that the C-terminal region of TDP-43, which mediates TDP-43-hnRNP interactions, is also required for self-regulation. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2010-12-02

    Endothelial nitric oxide modulates expression and processing of amyloid precursor protein

    ✓ Peer-reviewed Risk genes beyond APOE Circulation research

    Key finding: The link between these risk factors and AD has yet to be identified; however, a common feature is endothelial dysfunction, specifically, decreased bioavailability of nitric oxide (NO). +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2010-12-01

    Reimagining Alzheimer's disease--an age-based hypothesis

    ✓ Peer-reviewed Getting a diagnosis The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: It begins with the most widely accepted risk factor for developing Alzheimer's disease: age. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2010-12-01

    Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration

    ✓ Peer-reviewed Disease mechanisms Neuron

    Key finding: Recent advances in understanding these disorders indicate that brain dysfunction precedes neurodegeneration, but the role of tau is unclear. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →