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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 16,426–16,450 of 27,380 studies, newest first · page 658 of 1096.

January 2016 25

  1. 2016-01-01

    Alzheimer's disease: Targeting the Cholinergic System

    ✓ Peer-reviewed Disease mechanisms Current neuropharmacology

    Key finding: AD is the most ordinary cause of dementia affecting 25 million people worldwide. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-01-01

    Inflammatory Mechanisms and Oxidative Stress as Key Factors Responsible for Progression of Neurodegeneration: Role of Brain Innate Immune System

    ✓ Peer-reviewed Inflammation and the immune system CNS & neurological disorders drug targets

    Key finding: Elevated levels of several cytokines and chronic neuroinflammation have been associated with many neurodegenerative disorders of central nervous system like age-related macular degeneration, Alzheimer disease, multiple sclerosis, Parkinson's disease, Huntington' disease, and tauopathies.

    Full summary, score breakdown and related studies → Original source

  3. 2016-01-01

    Mild Cognitive Impairment and Dementia Prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)

    ✓ Peer-reviewed How common it is Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: MCI and dementia were common among survivors from the original ARIC cohort.

    Full summary, score breakdown and related studies → Original source

  4. 2016 no date recorded — placed by publication year

    Mild cognitive impairment and dementia prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study

    ✓ Peer-reviewed How common it is Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

    MCI and dementia were common among survivors from the original ARIC cohort.

    Full summary, score breakdown and related studies → Original source

  5. 2016-01-01

    TREM2 p.H157Y Variant and the Risk of Alzheimer's Disease: A Meta-Analysis Involving 14,510 Subjects

    ✓ Peer-reviewed TREM2 and immune genetics Current neurovascular research

    Key finding: We recently revealed that p.H157Y (rs2234255), a rare coding variant of triggering receptor expressed on myeloid cells 2 gene (TREM2), was associated with Alzheimer's disease (AD) susceptibility in Han Chinese. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2016-01-01

    Geographical Variation in Dementia Mortality in Italy, New Zealand, and Chile: The Impact of Latitude, Vitamin D, and Air Pollution

    ✓ Peer-reviewed Risk factors Dementia and Geriatric Cognitive Disorders

    Key finding: Dementia SMRs were higher in northern than central or southern Italy. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2016-01-01

    Rapid Acting Insulin Use and Persistence among Elderly Type 2 Diabetes Patients Adding RAI to Oral Antidiabetes Drug Regimens

    ✓ Peer-reviewed Health systems and care delivery Journal of Diabetes Research

    Key finding: Factors associated with RAIp included using ≤2 OADs; cognitive impairment, basal insulin use during follow-up; and higher RAI out-of-pocket costs ($36 to <$56 versus $0 to $6.30). +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2016-01-01

    New Approaches to Preventing Financial Exploitation: A Focus on the Banks

    ⚠ Report — not peer-reviewed Risk factors Public Policy & Aging Report

    Key finding: The largest increase in the older adult population in U.S. history is something to celebrate—yet, at the same time, current and future trends signal that financial exploitation is, and will continue to be, a significant threat for older adults. +4 more findings

    Scored 20 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  9. 2016-01-01

    The Gut-Brain Axis, Including the Microbiome, Leaky Gut and Bacterial Translocation: Mechanisms and Pathophysiological Role in Alzheimer's Disease

    ✓ Peer-reviewed Inflammation and the immune system Current pharmaceutical design

    Key finding: Though the primary risk factor for AD is advancing age, other factors such as diabetes mellitus, hyperlipidemia, obesity, vascular factors and depression play a role in its pathogenesis. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2016-01-01

    Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology

    ✓ Peer-reviewed Inflammation and the immune system Current Alzheimer research

    Key finding: The overexpression of the gene for the amyloid precursor protein (APP), on chromosome 21, leads to early onset beta-amyloid (Aβ) plaques in DS. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2016-01-01

    LPS-induced Murine Neuroinflammation Model: Main Features and Suitability for Pre-clinical Assessment of Nutraceuticals

    ✓ Peer-reviewed Inflammation and the immune system Current neuropharmacology

    Key finding: Based on current knowledge in the field, suggesting that targeting peripheral inflammation could be a promising additional treatment/prevention approach for neurodegenerative diseases, drugs and natural products with anti-inflammatory properties have been evaluated in animal models of neuroinflammation and neurodegeneration. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2016-01-01

    The Long Non-Coding RNAs in Neurodegenerative Diseases: Novel Mechanisms of Pathogenesis

    ✓ Peer-reviewed Brain tissue and pathology Current Alzheimer research

    Key finding: Long-non-coding RNAs (lncRNAs), RNA molecules longer than 200 nucleotides, have been involved in several biological processes and in a growing number of diseases, controlling gene transcription, pre-mRNA processing, the transport of mature mRNAs to specific cellular compartments, the regulation of mRNA stability, protein translation and turnover. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2016-01-01

    Optimization of Statistical Single Subject Analysis of Brain FDG PET for the Prognosis of Mild Cognitive Impairment-to-Alzheimer's Disease Conversion

    ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD

    Key finding: Positron emission tomography (PET) with the glucose analog F-18-fluorodeoxyglucose (FDG) is widely used in the diagnosis of neurodegenerative diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2016-01-01

    Associations between Neuropsychiatric Symptoms and Cerebral Amyloid Deposition in Cognitively Impaired Elderly People

    ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD

    Key finding: Neuropsychiatric symptoms, also known as behavioral and psychological symptoms of dementia (BPSD), affect the majority of patients with dementia, and result in a greater cognitive and functional impairment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2016-01-01

    Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study

    ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD

    Key finding: Identifying nutrition- and lifestyle-based risk factors for cognitive impairment and dementia may aid future primary prevention efforts. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2016-01-01

    Screening for Mild Cognitive Impairment: Comparison of "MCI Specific" Screening Instruments

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: Sensitive and specific instruments are required to screen for cognitive impairment (CI) in busy clinical practice. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2016-01-01

    Performance of Cerebrospinal Fluid Biomarkers of Alzheimer Disease in a Memory Clinic in Norway

    ✓ Peer-reviewed Tau biomarkers Alzheimer disease and associated disorders

    Key finding: Although Alzheimer disease (AD) remains a clinical diagnosis, biomarkers are in use to support the diagnosis. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2016-01-01

    Overexpression of TREM2 enhances glioma cell proliferation and invasion: a therapeutic target in human glioma

    ✓ Peer-reviewed TREM2 and immune genetics Oncotarget

    Key finding: Although TREM2 mutation is reported to be related to Nasu-Hakola disease and Alzheimer's disease, little is known about the association between TREM2 and gliomas. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2016-01-01

    Negative regulation of TLR signaling in myeloid cells--implications for autoimmune diseases

    ✓ Peer-reviewed TREM2 and immune genetics Immunological reviews

    Key finding: Whereas TLR-induced inflammatory mediators are required for pathogen clearance, many are toxic to the host and can cause pathological inflammation when over-produced. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2016-01-01

    Molecular Basis of Familial and Sporadic Alzheimer's Disease

    ✓ Peer-reviewed TREM2 and immune genetics Current Alzheimer research

    Key finding: Among the genetic factors are genes associated with a family history of the disease (familial AD, FAD) and sporadic AD (SAD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2016-01-01

    Association of Elevated Amyloid Levels With Cognition and Biomarkers in Cognitively Normal People From the Community

    ✓ Peer-reviewed Mild cognitive impairment JAMA neurology

    Key finding: In persons selected from a population-based study, elevated amyloid levels at baseline were associated with worse cognition and imaging biomarkers at baseline and with greater clinical decline and neurodegeneration. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2016-01-01

    Cognitive Impairment, Neuroimaging, and Alzheimer Neuropathology in Mouse Models of Down Syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Current Alzheimer research

    Key finding: The profound memory deficits associated with DS-related AD (DS-AD) have been associated with degeneration of several neuronal populations, but mechanisms of neurodegeneration are largely unexplored.

    Full summary, score breakdown and related studies → Original source

  23. 2016-01-01

    Isoprostanes - A novel major group of oxidative stress markers

    ✓ Peer-reviewed Down syndrome and Alzheimer's International journal of occupational medicine and environmental health

    Key finding: Isoprostanes are a recently discovered group of prostaglandin isomers. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2016-01-01

    The Language Profile of Behavioral Variant Frontotemporal Dementia

    ✓ Peer-reviewed Digital health tools Journal of Alzheimer's disease : JAD

    Key finding: Relative to healthy controls, and after accounting for nonverbal executive performance, patients with bvFTD showed deficits of noun and verb naming and single word comprehension, diminished spontaneous propositional speech, and deterioration in naming performance over time. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2016-01-01

    The neuropathology and cerebrovascular mechanisms of dementia

    ✓ Peer-reviewed How common it is Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

    Key finding: Recently, the National Plan to address Alzheimer’s Disease prioritized Alzheimer’s disease-related dementias to include: Alzheimer’s disease, dementia with Lewy bodies, frontotemporal dementia, vascular dementia, and mixed dementias. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →