Home › Research › How common it is
Mild cognitive impairment and dementia prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study
David S. Knopman, Rebecca F. Gottesman, Albert Richey Sharrett, Lisa Miller Wruck, Beverly Gwen Windham, Laura H. Coker, Andrea L.C. Schneider, Hengrui Sun, Álvaro Alonso, Josef Coresh, Marilyn S. Albert, Thomas H. Mosley. Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring, 2016
Topic: Risk, prevention and care in population studies
INTRODUCTION: We examined prevalence of mild cognitive impairment (MCI) and dementia in the Atherosclerosis Risk in Communities (ARIC) Neurocognitive Study. METHODS: Beginning in June, 2011, we invited all surviving ARIC participants to undergo cognitive, neurological and brain imaging assessments to diagnose MCI or dementia and assign an etiology for the cognitive disorder. RESULTS: Of 10713 surviving ARIC participants (age range 69-88 yrs), we ascertained cognitive diagnoses in 6471 in-person, 1966 by telephone interviews (participant or informant) and the remainder by medical record review. The prevalence of dementia was 9.0% and MCI 21%. Alzheimer's disease was the primary or secondary etiology in 76% of dementia and 75% of MCI participants. Cerebrovascular disease was the primary or secondary etiology in 46% of dementia and 32% of MCI participants. DISCUSSION: MCI and dementia were common among survivors from the original ARIC cohort. Nearly 30% of the ARIC cohort received diagnoses of either dementia or MCI, and for the majority of these individuals (about 75%) the etiologic basis was attributed to Alzheimer's disease.
Why it matters
Among 10713 surviving ARIC participants aged 69 to 88, dementia prevalence was 9.0% and mild cognitive impairment 21%. Alzheimer's disease was a primary or secondary cause in 76% of dementia and 75% of mild cognitive impairment, and cerebrovascular disease in 46% and 32%.
New to this subject? Start with our plain-English guide: Alzheimer's in numbers →
How this study scored 48/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on strength of evidence, so that was left out: it earned 46 of the 95 points we could judge it on, which is 48 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring) |
| Journal's citation record | 1 / 4 | Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring: journal h-index 86 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | — / 5 | No evidence rating recorded — left out of this score |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2016 — within 20 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 6 / 7 | Cited 313 times (OpenAlex, 2026-10-10) |
| Citations per year | 4 / 5 | 26.1 citations a year over 12 year(s) since 2016 |
| Impact for its field and year | 4 / 6 | Cited 20.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 3 / 4 | Cited 101 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Thomas H. Mosley: h-index 94 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | Johns Hopkins University: institution h-index 2,306 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 7 institution(s) in 1 country |
| Indexed in PubMed | 1 / 2 | Not in PubMed, but has a DOI |
| Free to read | 2 / 2 | Free to read |
| Points | 46 / 95 | Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 46 of the 95 points we could judge it on is 48 out of 100. |
| Total | 48 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1016/j.dadm.2015.12.002
- Original source →
- Free full text: Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 12 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
APA 7th
Knopman, D. S., Gottesman, R. F., Sharrett, A. R., Wruck, L. M., Windham, B. G., Coker, L. H., et al. (2016). Mild cognitive impairment and dementia prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study. Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring. https://doi.org/10.1016/j.dadm.2015.12.002
Vancouver
Knopman DS, Gottesman RF, Sharrett AR, Wruck LM, Windham BG, Coker LH, et al. Mild cognitive impairment and dementia prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study. Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring. 2016. doi:10.1016/j.dadm.2015.12.002.
BibTeX
@article{knopman2016-8aa6c32d,
author = {Knopman, David S. and Gottesman, Rebecca F. and Sharrett, Albert Richey and Wruck, Lisa Miller and Windham, Beverly Gwen and Coker, Laura H. and Schneider, Andrea L.C. and Sun, Hengrui and Alonso, Álvaro and Coresh, Josef and Albert, Marilyn S. and Mosley, Thomas H.},
title = {{Mild cognitive impairment and dementia prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study}},
journal = {Alzheimer s \& Dementia Diagnosis Assessment \& Disease Monitoring},
year = {2016},
doi = {10.1016/j.dadm.2015.12.002},
url = {https://doi.org/10.1016/j.dadm.2015.12.002}
}
Related studies in How common it is
Also tagged “biobank”
1,084 studies in the library carry the topic tag “biobank”; these are this study's neighbours in a fixed, alphabetical-by-hash tour of them, not the closest in content. All 1,084 tagged studies.