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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 15,176–15,200 of 27,380 studies, newest first · page 608 of 1096.

April 2017 10

  1. 2017-04-01

    Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis

    ✓ Peer-reviewed Brain scans and imaging Science translational medicine

    Key finding: Given that the predominant clinical and pathological features of FTD and NCL are distinct, it is controversial whether the disease mechanisms associated with complete and partial PGRN loss are similar or distinct. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2017-04-01

    Elucidating the Role of TREM2 in Alzheimer's Disease

    ✓ Peer-reviewed TREM2 and immune genetics Neuron

    Key finding: Genetic factors, such as rare variants in the microglial-expressed gene TREM2, strongly impact the lifetime risk of developing AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2017-04-01

    Motor Speech Phenotypes of Frontotemporal Dementia, Primary Progressive Aphasia, and Progressive Apraxia of Speech

    ✓ Peer-reviewed Digital health tools Journal of speech, language, and hearing research : JSLHR

    Key finding: Our review identified several measures of speech which may assist with diagnosis and classification, and consolidated the brain-behavior associations relating to speech in FTD, PPA, and progressive apraxia of speech.

    Full summary, score breakdown and related studies → Original source

  4. 2017-04-01

    Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study

    ✓ Peer-reviewed Brain scans and imaging Alzheimer disease and associated disorders

    Key finding: Metformin was associated with improved executive functioning, and trends suggested improvement in learning/memory and attention. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2017-04-01

    Type 2 diabetes and quality of life

    ✓ Peer-reviewed Getting a diagnosis World journal of diabetes

    Key finding: Until now, the studies performed, have demonstrated little to moderate benefit.

    Full summary, score breakdown and related studies → Original source

  6. 2017-04-01

    Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes

    ✓ Peer-reviewed Prevention and risk Circulation research

    Key finding: Both heart failure and myocardial infarction increase risk of AF and vice versa creating a feed-forward loop that increases mortality. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2017-04-01

    Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases

    ✓ Peer-reviewed Genetics Journal of neuropathology and experimental neurology

    Key finding: We found that (i) the amygdala is a hotspot for all ARTAG types; (ii) age at death, male sex, and presence of primary frontotemporal lobar degeneration (FTLD) tauopathy are significantly associated with ARTAG; (iii) age at death, greater degree of brain atrophy, ventricular enlargement, and Alzheimer disease (AD)-related variables are associated with subpial, white matter, and perivascular ARTAG types; (iv) AD-related variables are associated particularly with lobar white matter ARTAG; and (v) gray matter ARTAG in primary FTLD-tauopathies appears in areas without neuronal tau pathology.

    Full summary, score breakdown and related studies → Original source

  8. 2017-04-01

    Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition

    ✓ Peer-reviewed Genetics JAMA

    Key finding: An increasing number of midlife vascular risk factors was significantly associated with elevated amyloid SUVR; this association was not significant for late-life risk factors. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2017-04-01

    Tau-PET Binding Distinguishes Patients With Early-stage Posterior Cortical Atrophy From Amnestic Alzheimer Disease Dementia

    ✓ Peer-reviewed Biomarkers Alzheimer disease and associated disorders

    Key finding: Flortaucipir uptake distinguished individuals with PCA and amnestic AD dementia early in the symptomatic course. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2017-04-01

    Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: In all 6 patients (3 women and 3 men; mean age 61.8 years), the underlying clinical phenotype was associated with the regional distribution of the [18F]AV-1451 signal. +3 more findings

    Full summary, score breakdown and related studies → Original source

March 2017 15

  1. 2017-03-31

    Tau Pathology Distribution in Alzheimer's disease Corresponds Differentially to Cognition-Relevant Functional Brain Networks

    ✓ Peer-reviewed Brain scans and imaging Frontiers in Neuroscience

    Key finding: Neuropathological studies have shown that the typical neurofibrillary pathology of hyperphosphorylated tau protein in Alzheimer’s disease (AD) preferentially affects specific brain regions whereas others remain relatively spared. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2017-03-31

    Improvement of Cognitive Function after Computer-Based Cognitive Training in Early Stage of Alzheimer's Dementia

    ✓ Peer-reviewed Prevention trials Dementia and neurocognitive disorders

    Key finding: Computer-based cognitive training might have beneficial effects on the general cognitive functions in early stage of Alzheimer's dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2017-03-31

    Not just amyloid: physiological functions of the amyloid precursor protein family

    ✓ Peer-reviewed Risk genes beyond APOE Nature reviews. Neuroscience

    Key finding: By contrast, the physiological functions of APP and the closely related APP-like proteins (APLPs) remain less well understood. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2017-03-30

    The midlife cognitive profiles of adults at high risk of late-onset Alzheimer's disease: The PREVENT study

    ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Middle-aged adults at risk of dementia show evidence of poorer cognitive performance, principally in visuospatial functions.

    Full summary, score breakdown and related studies → Original source

  5. 2017-03-30

    Validation of the Spanish-language version of the Montreal Cognitive Assessment test in adults older than 60 years

    ✓ Peer-reviewed Cognitive tests and assessment Neurologia

    Key finding: Few studies have validated the Spanish-language version of the Montreal Cognitive Assessment (MoCA-S) test in Latin American populations. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2017-03-30

    FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons

    ✓ Peer-reviewed Lewy body dementia Nature communications

    Key finding: Most circRNAs are conserved in humans and specific ones are deregulated in human-induced pluripotent stem cell-derived MNs carrying the FUS P525L mutation associated with ALS.

    Full summary, score breakdown and related studies → Original source

  7. 2017-03-29

    Virtual Reality for Management of Pain in Hospitalized Patients: Results of a Controlled Trial

    ✓ Peer-reviewed Vascular contributions JMIR mental health

    Key finding: Use of VR in hospitalized patients significantly reduces pain versus a control distraction condition. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2017-03-29

    Parental family history of dementia in relation to subclinical brain disease and dementia risk

    ✓ Peer-reviewed Long-term cohort studies Neurology

    Key finding: From 2000 to 2002, we assessed parental history of dementia in participants without dementia of the Rotterdam Study. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2017-03-29

    Risk factors associated with the onset and progression of Alzheimer's disease: A systematic review of the evidence

    ✓ Peer-reviewed Prevention and risk Neurotoxicology

    Key finding: A systematic review was conducted to identify risk factors associated with the onset and progression of Alzheimer's disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2017-03-28

    ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Consistently, significantly elevated levels of ErbB2 were confirmed in the hippocampus of human AD brains. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2017-03-28

    Altered Synapse Stability in the Early Stages of Tauopathy

    ✓ Peer-reviewed Disease mechanisms Cell reports

    Key finding: Synapse loss is a key feature of dementia, but it is unclear whether synaptic dysfunction precedes degenerative phases of the disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2017-03-28

    Population-based stroke and dementia incidence trends: Age and sex variations

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The concomitant decline in stroke and dementia incidence rates may depict how successful stroke prevention has targeted shared risk factors of both conditions, especially at advanced ages where such risk factors are highly prevalent.

    Full summary, score breakdown and related studies → Original source

  13. 2017-03-28

    The role of cognitive activity in cognition protection: from Bedside to Bench

    ✓ Peer-reviewed Prevention trials Translational neurodegeneration

    Key finding: The positive effects of cognitive activity is closely related with neural plasticity, neurotrophin, neurotransmitter and neuromodulator signaling pathway changes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2017-03-28

    The impact of individual Cognitive Stimulation Therapy (iCST) on cognition, quality of life, caregiver health, and family relationships in dementia: A randomised controlled trial

    ✓ Peer-reviewed Cognitive tests and assessment PLoS medicine

    Key finding: Cognitive stimulation therapy (CST) is a well-established group psychosocial intervention for people with dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2017-03-28

    APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases

    ✓ Peer-reviewed Risk genes beyond APOE PLoS medicine

    Key finding: Amyloid protein precursor (APP), presenilin-1 (PSEN1), and presenilin-2 (PSEN2) mutations cause autosomal dominant forms of early-onset Alzheimer disease (AD-EOAD). +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →