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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26889 of the 27780 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 16,301–16,325 of 27,780 studies, newest first · page 653 of 1112.

May 2016 25

  1. 2016-05-30

    A large-scale comparison of cortical thickness and volume methods for measuring Alzheimer's disease severity

    ✓ Peer-reviewed Hippocampus size on brain scans NeuroImage. Clinical

    Key finding: We show that volume- and thickness-based measures generally perform similarly for separating clinically normal from AD populations, and in correlation with Braak neurofibrillary tangle stage at autopsy. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-05-30

    Remote Neuropsychological Assessment in Rural American Indians with and without Cognitive Impairment

    ✓ Peer-reviewed Disparities Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

    Key finding: The sample consisted of 84 participants from the Choctaw Nation in Oklahoma, including 53 females and 31 males [M age = 64.89 (SD = 9.73), M education = 12.58 (SD = 2.35)]. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2016-05-26

    Particulate Air Pollution and Fasting Blood Glucose in Nondiabetic Individuals: Associations and Epigenetic Mediation in the Normative Aging Study, 2000-2011

    ✓ Peer-reviewed Risk factors Environmental health perspectives

    Key finding: Among nondiabetics, short- and medium-term PM2.5 were associated with higher FBG. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2016-05-26

    Preclinical Characterization of 18F-MK-6240, a Promising PET Tracer for In Vivo Quantification of Human Neurofibrillary Tangles

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: A PET tracer is desired to help guide the discovery and development of disease-modifying therapeutics for neurodegenerative diseases characterized by neurofibrillary tangles (NFTs), the predominant tau pathology in Alzheimer disease (AD).

    Full summary, score breakdown and related studies → Original source

  5. 2016-05-26

    Pathophysiological Role of Neuroinflammation in Neurodegenerative Diseases and Psychiatric Disorders

    ✓ Peer-reviewed Inflammation and the immune system International neurourology journal

    Key finding: While the underlying mechanisms remain poorly understood, human and animal studies have supported a role of neuroinflammation in the etiology of these diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2016-05-26

    Defining the spectrum of frontotemporal dementias associated with TARDBP mutations

    ✓ Peer-reviewed Disparities Neurology. Genetics

    Key finding: We describe the largest series of patients with TARDBP mutations presenting with frontotemporal dementia (FTD) and review the cases in the literature to precisely characterize FTD diseases associated with this genotype. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2016-05-25

    Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease

    ✓ Peer-reviewed Treatments Frontiers in neuroscience

    Key finding: Although its etiology is not completely known, several factors including deficits of acetylcholine, β-amyloid deposits, τ-protein phosphorylation, oxidative stress, and neuroinflammation are considered to play significant roles in the pathophysiology of this disease.

    Full summary, score breakdown and related studies → Original source

  8. 2016-05-25

    Mitochondria-associated ER membranes and Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Current opinion in genetics & development

    Key finding: The most widely accepted hypothesis is called the amyloid cascade, based on the observation that the brains of AD patients contain high levels of extracellular plaques, composed mainly of β-amyloid (Aβ), and intracellular tangles, composed of hyperphosphorylated forms of the microtubule-associated protein tau. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2016-05-24

    Self, cortical midline structures and the resting state: Implications for Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Neuroscience and biobehavioral reviews

    Key finding: Different aspects of the self have been reported to be affected in many neurological or psychiatric diseases such as Alzheimer's disease (AD), including mainly higher-level cognitive self-unawareness. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2016-05-24

    In Alzheimer's Disease, 6-Month Treatment with GLP-1 Analog Prevents Decline of Brain Glucose Metabolism: Randomized, Placebo-Controlled, Double-Blind Clinical Trial

    ✓ Peer-reviewed Drug development Frontiers in aging neuroscience

    Key finding: The PIB binding increased significantly in temporal lobe in placebo and treatment patients (both P = 0.04), and in occipital lobe in treatment patients (P = 0.04). +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2016-05-24

    Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

    ✓ Peer-reviewed Genetics Biological psychiatry

    Key finding: We demonstrate that using additional phenotype data previously collected by genetic studies to tackle phenotypic heterogeneity in MDD can successfully lead to the discovery of genetic risk factor despite reduced sample size. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2016-05-24

    Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers Neurobiology of disease

    Key finding: In wild type mice, we show that Aβ40 (fluorescently labeled Aβ40 or unlabeled Aβ40), was distributed from CSF to brain, via the peri-arterial space, and associated with neurons. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2016-05-24

    Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimer's disease brain

    ✓ Peer-reviewed Disease mechanisms Mechanisms of ageing and development

    Key finding: It has been shown that insulin resistance impairs glucose metabolism and mitochondrial function, thus increasing production of reactive oxygen species. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2016-05-23

    Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease

    ✓ Peer-reviewed Brain tissue and pathology American journal of human genetics

    Key finding: Late-onset, sporadic Alzheimer disease (AD) is a common and lethal neurodegenerative disorder and many germline inherited variants have been found to influence the risk of developing AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2016-05-22

    Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia

    ✓ Peer-reviewed Disease mechanisms Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Our findings suggest that the proposition that synaptic markers can predict cognitive decline in AD, should be extended to Lewy body diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2016-05-21

    "New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS)

    ✓ Peer-reviewed Disease mechanisms Journal of neuropathology and experimental neurology

    Key finding: After demonstrating the importance of correct disease classification for AD and primary age-related tauopathy, we emphasize the public health impact of an underappreciated AD "mimic," which has been termed "hippocampal sclerosis of aging" or "hippocampal sclerosis dementia."

    Full summary, score breakdown and related studies → Original source

  17. 2016-05-20

    Molecular Mechanisms of Vascular Dementia: What Can Be Learned from Animal Models of Chronic Cerebral Hypoperfusion?

    ✓ Peer-reviewed Inflammation and the immune system Molecular neurobiology

    Key finding: Numerous studies have demonstrated that chronic cerebral hypoperfusion (CCH) is associated with the initiation and progression of VD and Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2016-05-19

    Biomarkers for dementia and mild cognitive impairment in Parkinson's disease

    ✓ Peer-reviewed Mild cognitive impairment Movement disorders : official journal of the Movement Disorder Society

    Key finding: Because it is not currently known which type of mild cognitive impairment confers a higher risk of progression to dementia, it would be useful to define biomarkers that could identify these patients to better study disease progression and possible interventions. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2016-05-18

    Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility

    ✓ Peer-reviewed Genetics European journal of human genetics : EJHG

    Key finding: We have applied the methodology to identify and characterise loci associated with susceptibility to type 2 diabetes (T2D) using GWAS data from the Resource for Genetic Epidemiology on Adult Health and Aging, a large multi-ethnic population-based cohort, created for investigating the genetic and environmental basis of age-related diseases.

    Full summary, score breakdown and related studies → Original source

  20. 2016-05-18

    Nanoparticle-mediated brain drug delivery: Overcoming blood-brain barrier to treat neurodegenerative diseases

    ✓ Peer-reviewed Inflammation and the immune system Journal of controlled release : official journal of the Controlled Release Society

    Key finding: Failure in maintaining any of these components results in the breakdown of this specialized multicellular structure and consequently promotes neuroinflammation and neurodegeneration.

    Full summary, score breakdown and related studies → Original source

  21. 2016-05-18

    A meta-review of stress, coping and interventions in dementia and dementia caregiving

    ✓ Peer-reviewed Caregiving BMC geriatrics

    Key finding: This meta-review supports the conclusion that being a caregiver for people with dementia is associated with psychological stress and physical ill-health. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2016-05-17

    Longitudinal noninvasive magnetic resonance imaging of brain microhemorrhages in BACE inhibitor-treated APP transgenic mice

    ✓ Peer-reviewed Drug development Neurobiology of aging

    Key finding: A crucial mechanism-related safety concern is the exacerbation of microhemorrhages, which are already present in the majority of Alzheimer patients. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2016-05-17

    Genes associated with Alzheimer's disease: an overview and current status

    ✓ Peer-reviewed Caregiving Clinical interventions in aging

    Key finding: Genome-wide association studies have revolutionized genetic research and have identified over 20 genetic loci associated with late-onset AD.

    Full summary, score breakdown and related studies → Original source

  24. 2016-05-17

    ABCA7 frameshift deletion associated with Alzheimer disease in African Americans

    ✓ Peer-reviewed Genetics Neurology. Genetics

    Key finding: This common ABCA7 deletion could represent an ethnic-specific pathogenic alteration in AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2016-05-16

    Risk Factors for Malnutrition in Older Adults: A Systematic Review of the Literature Based on Longitudinal Data

    ✓ Peer-reviewed Clinical safety Advances in nutrition (Bethesda, Md.)

    Key finding: These studies reported the following significant risk factors for malnutrition: age (OR: 1.038; P = 0.045), frailty in institutionalized persons (β: 0.22; P = 0.036), excessive polypharmacy (β: -0.62; P = 0.001), general health decline including physical function (OR: 1.793; P = 0.008), Parkinson disease (OR: 2.450; P = 0.047), constipation (OR: 2.490; P = 0.015), poor (OR: 3.30; P value not given) or moderate (β: -0.27; P = 0.016) self-reported health status, cognitive decline (OR: 1.844; P = 0.001), dementia (OR: 2.139; P = 0.001), eating dependencies (OR: 2.257; P = 0.001), loss of interest in life (β: -0.58; P = 0.017), poor appetite (β: -1.52; P = 0.000), basal oral dysphagia (OR: 2.72; P = 0.010), signs of impaired efficacy of swallowing (OR: 2.73; P = 0.015), and institutionalization (β: -1.89; P < 0.001).

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →