Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 16,176–16,200 of 27,380 studies, newest first · page 648 of 1096.
April 2016 16
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2016-04-01
Metabolic Syndrome and the Risk of Mild Cognitive Impairment and Progression to Dementia: Follow-up of the Singapore Longitudinal Ageing Study Cohort
65/100 ✓ Peer-reviewed Mild cognitive impairment JAMA neurology
Key finding: The MetS was associated with an increased incidence of MCI and progression to dementia. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-04-01
Treatment of Alzheimer Disease With CT Scans: A Case Report
38/100 ✓ Peer-reviewed Digital health tools Dose-response : a publication of International Hormesis Society
Key finding: Alzheimer disease (AD) primarily affects older adults. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-04-01
Mild Cognitive Impairment
46/100 ✓ Peer-reviewed How common it is Continuum (Minneapolis, Minn.)
Key finding: As individuals age, the quality of cognitive function becomes an increasingly important topic. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-04-01
Effectiveness of Supporting Informal Caregivers of People with Dementia: A Systematic Review of Randomized and Non-Randomized Controlled Trials
58/100 ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD
Key finding: Despite methodological inconsistency, supporting caregivers appears to be an effective strategy often improving well-being of caregiver or care-recipient and resulting in additional benefits for society.
Full summary, score breakdown and related studies → Original source
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2016-04-01
The Prevalence and Incidence of Dementia with Lewy Bodies: a Systematic Review
65/100 ✓ Peer-reviewed Caregiving The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
Key finding: DLB becomes more common with increasing age and accounts for about 5% of all dementia cases in older populations.
Full summary, score breakdown and related studies → Original source
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2016-04-01
The Prevalence and Incidence of Frontotemporal Dementia: a Systematic Review
65/100 ✓ Peer-reviewed Caregiving The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
Key finding: Population-based estimates for the epidemiology of FTD varied widely in the included studies. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-04-01
The Prevalence and Incidence of Dementia Due to Alzheimer's Disease: a Systematic Review and Meta-Analysis
66/100 ✓ Peer-reviewed Caregiving The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
Key finding: The burden of AD dementia is substantial. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-04-01
2016 Alzheimer's disease facts and figures
56/100 ✓ Peer-reviewed Caregiving Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: This report describes the public health impact of Alzheimer's disease, including incidence and prevalence, mortality rates, costs of care, and the overall impact on caregivers and society.
Full summary, score breakdown and related studies → Original source
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2016-04-01
Prevalence, characteristics, and survival of frontotemporal lobar degeneration syndromes
58/100 ✓ Peer-reviewed Getting a diagnosis Neurology
Key finding: Key features of this study include the revised diagnostic criteria with improved specificity and sensitivity, an unrestricted age range, and simultaneous assessment of multiple FTLD syndromes. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-04-01
Aging and Hearing Health: The Life-course Approach
49/100 ✓ Peer-reviewed Prevention and risk The Gerontologist
Key finding: In adults, disabling hearing loss is defined by thresholds greater than 40 dBHL in the better hearing ear.
Full summary, score breakdown and related studies → Original source
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2016-04-01
Updating the Evidence for Physical Activity: Summative Reviews of the Epidemiological Evidence, Prevalence, and Interventions to Promote "Active Aging"
49/100 ✓ Peer-reviewed Prevention and risk The Gerontologist
Key finding: Purpose of the study There is a global imperative to increase awareness of the emerging evidence on physical activity (PA) among older adults.
Full summary, score breakdown and related studies → Original source
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2016-04-01
Association of Proton Pump Inhibitors With Risk of Dementia: A Pharmacoepidemiological Claims Data Analysis
70/100 ✓ Peer-reviewed Prevention and risk JAMA neurology
Key finding: The patients receiving regular PPI medication (n = 2950; mean [SD] age, 83.8 [5.4] years; 77.9% female) had a significantly increased risk of incident dementia compared with the patients not receiving PPI medication (n = 70,729; mean [SD] age, 83.0 [5.6] years; 73.6% female) (hazard ratio, 1.44 [95% CI, 1.36-1.52]; P Conclusions and relevance The avoidance of PPI medication may prevent the development of dementia. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-04-01
Feasibility of a Memory Clinic-Based Physical Activity Prescription Program
55/100 ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD
Key finding: Setup and daily use of mHealth technology appears to be feasible for a person with cognitive impairment with the help of a partner, but increasing daily step counts over 8 weeks was not achieved.
Full summary, score breakdown and related studies → Original source
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2016-04-01
Effects of Exercise on Cognition: The Finnish Alzheimer Disease Exercise Trial: A Randomized, Controlled Trial
67/100 ✓ Peer-reviewed Treatments Journal of the American Geriatrics Society
Key finding: Regular, long-term, customized HE improved the executive function of community-dwelling older people with memory disorders, but the effects were mild and were not observed in other domains of cognition. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-04-01
Cognitive Decline in a Colombian Kindred With Autosomal Dominant Alzheimer Disease: A Retrospective Cohort Study
60/100 ✓ Peer-reviewed Genetics JAMA neurology
Key finding: After the change point, carriers had a statistically significant cognitive decline with a loss of 0.24 (95% CI, -0.26 to -0.22) points per year for the word list recall test and 2.13 (95% CI, -2.29 to -1.96) points per year for total scores. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-04-01
Alzheimer Disease
43/100 ✓ Peer-reviewed Biomarkers Continuum (Minneapolis, Minn.)
Key finding: This article discusses the recent advances in the diagnosis and treatment of Alzheimer disease (AD).
Full summary, score breakdown and related studies → Original source
March 2016 9
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2016-03-31
Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration
43/100 ✓ Peer-reviewed Risk factors Nature communications
Key finding: We find that rotenone, a pesticide associated with Parkinson's disease risk, and certain fungicides, including pyraclostrobin, trifloxystrobin, famoxadone and fenamidone, produce transcriptional changes in vitro that are similar to those seen in brain samples from humans with autism, advanced age and neurodegeneration (Alzheimer's disease and Huntington's disease).
Full summary, score breakdown and related studies → Original source
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2016-03-31
Beyond Dizziness: Virtual Navigation, Spatial Anxiety and Hippocampal Volume in Bilateral Vestibulopathy
40/100 ✓ Peer-reviewed Hippocampus size on brain scans Frontiers in human neuroscience
Key finding: MRI revealed a significant decrease in the gray matter mid-hippocampal volume (Left: p = 0.006, Z = 4.58, Right: p < 0.001, Z = 3.63) and posterior parahippocampal volume (Right: p = 0.005, Z = 4.65, Left: p < 0.001, Z = 3.87) compared to those of healthy controls.
Full summary, score breakdown and related studies → Original source
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2016-03-31
No Association between Dietary Patterns and Risk for Cognitive Decline in Older Women with 9-Year Follow-Up: Data from the Women's Health Initiative Memory Study
62/100 ✓ Peer-reviewed Prevention trials Journal of the Academy of Nutrition and Dietetics
Key finding: Dietary patterns characterized by the aMED, HEI-2010, AHEI-2010, or DASH dietary score were not associated with cognitive decline in older women. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-03-31
Oligomeropathies and pathogenesis of Alzheimer and Parkinson's diseases
36/100 ✓ Peer-reviewed Disease mechanisms Movement disorders : official journal of the Movement Disorder Society
Key finding: The term oligomeropathies defines the neurodegenerative disorders associated with protein misfolding, where small soluble aggregates (oligomers 4-200 KDa) are the cause of neuronal dysfunction and are responsible for spreading the pathology. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-03-31
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss
36/100 ✓ Peer-reviewed Disease mechanisms Neuron
Key finding: In AD patients with dementia, we found enhanced tau acetylation is linked to loss of KIBRA. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-03-31
Neuropsychological Criteria for Mild Cognitive Impairment and Dementia Risk in the Framingham Heart Study
53/100 ✓ Peer-reviewed Mild cognitive impairment Journal of the International Neuropsychological Society : JINS
Key finding: The Petersen/Winblad criteria classified 34% of participants as having MCI while the Jak/Bondi criteria classified 24% as MCI. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-03-31
Amyloid Proteins and Their Role in Multiple Sclerosis. Considerations in the Use of Amyloid-PET Imaging
39/100 ✓ Peer-reviewed Biomarkers Frontiers in neurology
Key finding: These tracers bind extensively to white matter, which suggests that they may be useful in studies of multiple sclerosis (MS), and that proteins resulting from proteolytic processing of the amyloid precursor protein (APP) may contribute to MS. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-03-31
Complement and microglia mediate early synapse loss in Alzheimer mouse models
64/100 ✓ Peer-reviewed Brain tissue and pathology Science (New York, N.Y.)
Key finding: Involvement of microglia and complement in AD has been attributed to neuroinflammation, prominent late in disease. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-03-30
The Differentiation of Amnestic Type MCI from the Non-Amnestic Types by Structural MRI
42/100 ✓ Peer-reviewed Mild cognitive impairment Frontiers in aging neuroscience
Key finding: The amnestic mild cognitive impairment/non-amnestic mild cognitive impairment separation is not only theoretical but backed by structural imaging methods and neuropsychological tests. +3 more findings
Full summary, score breakdown and related studies → Original source
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