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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 14,701–14,725 of 27,380 studies, newest first · page 589 of 1096.

October 2017 16

  1. 2017-10-01

    The advance care planning experiences of people with dementia, family caregivers and professionals: a synthesis of the qualitative literature

    ✓ Peer-reviewed End-of-life care Annals of palliative medicine

    Key finding: Take up of ACP within the dementia population is low, especially when compared with other conditions. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2017-10-01

    Palliative Care in Neurology

    ✓ Peer-reviewed End-of-life care Mayo Clinic proceedings

    Key finding: Neurologic conditions tend to have high symptom burdens, variable disease courses, and poor prognoses that affect not only patients but also their families and caregivers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2017-10-01

    Barriers to palliative care for advanced dementia: a scoping review

    ✓ Peer-reviewed End-of-life care Annals of palliative medicine

    Key finding: The aims of this study were to assess the barriers associated with a lack of implementation of palliative care for people with dementia and to explore whether there is a gap in knowledge necessitating further study. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2017-10-01

    Research Gaps and Controversies in Chronic Traumatic Encephalopathy: A Review

    ✓ Peer-reviewed Disease mechanisms JAMA neurology

    Key finding: Available data, while limited and complicated by selection bias, indicate that exposure to RBT represents the greatest risk factor for CTE pathological features, although clinicopathological correlates and the nature of onset and progression of symptoms are largely unknown. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2017-10-01

    Contribution of Socioeconomic Status at 3 Life-Course Periods to Late-Life Memory Function and Decline: Early and Late Predictors of Dementia Risk

    ✓ Peer-reviewed Brain tissue and pathology American journal of epidemiology

    Key finding: Further, the relative importance of different life-course periods for rate of late-life memory decline has not been evaluated. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2017-10-01

    TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant

    ✓ Peer-reviewed TREM2 and immune genetics EMBO molecular medicine

    Key finding: In all cell types, a soluble 17 kDa N-terminal cleavage fragment was shed into the conditioned media in a constitutive process that is inhibited by G1254023X and metalloprotease inhibitors and siRNA targeting ADAM10. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2017-10-01

    An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function

    ✓ Peer-reviewed Risk genes beyond APOE EMBO molecular medicine

    Key finding: TREM2 matures within the secretory pathway, and its ectodomain is shed on the plasma membrane. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2017-10-01

    Factors underlying cognitive decline in old age and Alzheimer's disease: the role of the hippocampus

    ✓ Peer-reviewed Mild cognitive impairment Reviews in the neurosciences

    Key finding: There are many factors that strongly influence the aetiology, development, and progression of cognitive decline in old age, mild cognitive impairment (MCI), and Alzheimer's disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2017-10-01

    The prevalence and progression of mild cognitive impairment among clinic and community populations: a systematic review and meta-analysis

    ✓ Peer-reviewed Mild cognitive impairment International psychogeriatrics

    Key finding: Age and gender were observed to be associated with MCI, in which age was considered as an impact factor for DR. The strong heterogeneity may result from variations in study design and baselines. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2017-10-01

    Glymphatic MRI in idiopathic normal pressure hydrocephalus

    ✓ Peer-reviewed Risk factors Brain : a journal of neurology

    Key finding: In idiopathic normal pressure hydrocephalus, we found delayed enhancement (P < 0.05) and decreased clearance of gadobutrol (P < 0.05) at the Sylvian fissure.

    Full summary, score breakdown and related studies → Original source

  11. 2017-10-01

    Evolving Notions of Schizophrenia as a Developmental Neurocognitive Disorder

    ✓ Peer-reviewed Disparities Journal of the International Neuropsychological Society : JINS

    Key finding: The centrality of neurocognition has been recognized, especially because neurocognitive deficits are strongly related to social and role functioning in the illness, and as a result neurocognitive measures are used routinely in clinical assessment of individuals with schizophrenia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2017-10-01

    Baseline Characteristics of Participants in the ASPREE (ASPirin in Reducing Events in the Elderly) Study

    ✓ Peer-reviewed Disparities The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Recruitment ended in December 2014 with 16,703 Australian and 2,411 U.S. participants, a median age of 74 (range 65-98) years and 56% women.

    Full summary, score breakdown and related studies → Original source

  13. 2017-10-01

    Effectiveness and Safety of Dementia Care Management in Primary Care: A Randomized Clinical Trial

    ✓ Peer-reviewed Caregiving JAMA psychiatry

    Key finding: The mean age of 634 patients was 80 years. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2017-10-01

    18 F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: 18 F-flortaucipir uptake was elevated in PSP versus controls and PD patients in a pattern consistent with the expected distribution of tau pathology. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2017-10-01

    Associations Between Midlife Vascular Risk Factors and 25-Year Incident Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort

    ✓ Peer-reviewed Prevention and risk JAMA neurology

    Key finding: Midlife vascular risk factors are associated with increased risk of dementia in black and white ARIC Study participants. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2017-10-01

    Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: Contrary to long-standing views, men and women with the APOE ε3/ε4 genotype have nearly the same odds of developing AD from age 55 to 85 years, but women have an increased risk at younger ages. +4 more findings

    Full summary, score breakdown and related studies → Original source

September 2017 9

  1. 2017-09-28

    Dendritic spine pathology and thrombospondin-1 deficits in Down syndrome

    ✓ Peer-reviewed Disease mechanisms Free radical biology & medicine

    Key finding: Abnormal dendritic spine structure and function is one of the most prominent features associated with neurodevelopmental disorders including Down syndrome (DS).

    Full summary, score breakdown and related studies → Original source

  2. 2017-09-28

    The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D

    ✓ Peer-reviewed Genetics Cell metabolism

    Key finding: We show that glial and neuronal monocarboxylate transporters (MCTs), fatty acid transport proteins (FATPs), and apolipoproteins are critical for glial LD formation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2017-09-28

    Genetic, Transcriptome, Proteomic, and Epidemiological Evidence for Blood-Brain Barrier Disruption and Polymicrobial Brain Invasion as Determinant Factors in Alzheimer's Disease

    ✓ Peer-reviewed TREM2 and immune genetics Journal of Alzheimer's disease reports

    Key finding: A bioinformatics survey showed that AD genome-wide association study (GWAS) genes (localized in bone marrow, immune locations and microglia) relate to multiple host/pathogen interactomes ( Candida albicans , Cryptococcus neoformans , Bornavirus, Borrelia burgdorferri , cytomegalovirus, Ebola virus, HSV-1, HERV-W, HIV-1, Epstein-Barr, hepatitis C, influenza, Chlamydia pneumoniae , Porphyrymonas gingivalis , Helicobacter pylori, Toxoplasma gondii, Trypanosoma cruzi ). +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2017-09-28

    Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia

    ✓ Peer-reviewed Prevention and risk Clinical science (London, England : 1979)

    Key finding: Increasing evidence suggests that vascular risk factors contribute to neurodegeneration, cognitive impairment and dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2017-09-27

    The value of subtraction MRI in detection of amyloid-related imaging abnormalities with oedema or effusion in Alzheimer's patients: An interobserver study

    ✓ Peer-reviewed Treatments European radiology

    Key finding: Subtraction MRI has potential as a visual aid increasing the sensitivity of ARIA-E assessment. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2017-09-27

    Brain network connectivity differs in early-onset neurodegenerative dementia

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Disease-specific patterns of functional network topology and connectivity alterations were observed in patients with EOAD and bvFTD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2017-09-27

    Metformin vs sulfonylurea use and risk of dementia in US veterans aged ≥65 years with diabetes

    ✓ Peer-reviewed Prevention and risk Neurology

    Key finding: Mean age was 73.5 years and mean HbA1c was 6.8%. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2017-09-25

    Neurofilaments and tau proteins in cerebrospinal fluid and serum in dementias and neuroinflammation

    ✓ Peer-reviewed Tau biomarkers Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia

    Key finding: The ratio CSF p-tau/t-tau was significantly higher in the NC group than that in the AD or OD groups (P<0.0005 for each group). +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2017-09-25

    Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's Disease

    ✓ Peer-reviewed Brain scans and imaging NeuroImage. Clinical

    Key finding: Regionally, 18 F-AV1451 was largely associated with local/adjacent GMR whereas frontal 11 C-PiB correlated with GMR in posterior regions. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →