Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 27,201–27,225 of 27,380 studies, newest first · page 1089 of 1096.

May 1987 2

  1. 1987-05-01

    Senile dementia of the Alzheimer type without neocortical neurofibrillary tangles

    ✓ Peer-reviewed Disparities Journal of neuropathology and experimental neurology

    Key finding: However, in a large series of cases (60) over age 74 a significant minority (30%) lacked neocortical tangles. +3 more findings

  2. 1987-05-01

    Psychological, social, and health consequences of caring for a relative with senile dementia

    ✓ Peer-reviewed Caregiving Journal of the American Geriatrics Society

    Key finding: Caregivers reported significantly higher levels of depression and negative affect toward their relatives, and lower overall life satisfaction than controls. +2 more findings

April 1987 5

  1. 1987-04-01
  2. 1987-04-01

    A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Journal of the neurological sciences

    Key finding: Values of synapse to neurone ratio also demonstrated this greater loss of synapses, there being on average 38% fewer synapses associated with each surviving neurone in layers II-III of the temporal cortex, 30% fewer in layer V, and a deficit of 14% in layer V of the frontal cortex. +1 more finding

  3. 1987-04-01

    Rapid eye movement sleep behavior disorder. A treatable parasomnia affecting older adults

    ✓ Peer-reviewed Brain scans and imaging JAMA

    Key finding: All patients underwent standard polysomnographic studies with videotaping of behaviors and extensive neurologic and psychiatric evaluations. +4 more findings

  4. 1987-04-01
  5. 1987-04-01

    Amyloid of neurofibrillary tangles of Guamanian parkinsonism-dementia and Alzheimer disease share identical amino acid sequence

    ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Our observations indicate that the brain amyloids of these diseases have a common subunit protein, which would also indicate a common pathogenesis.

March 1987 2

  1. 1987-03-01

    Beta amyloid gene duplication in Alzheimer's disease and karyotypically normal Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Science (New York, N.Y.)

    Key finding: With the recently cloned complementary DNA probe, lambda Am4 for the chromosome 21 gene encoding brain amyloid polypeptide (beta amyloid protein) of Alzheimer's disease, leukocyte DNA from three patients with sporadic Alzheimer's disease and two patients with karyotypically normal Down syndrome was found to contain three copies of this gene. +1 more finding

  2. 1987-03-01

    Falls and fractures in patients with Alzheimer-type dementia

    ✓ Peer-reviewed Prevention and risk JAMA

    Key finding: During follow-up, 50% either fell or became unable to walk. +4 more findings

February 1987 7

  1. 1987-02-20

    Conservation of Brain Amyloid Proteins in Aged Mammals and Humans with Alzheimer's Disease

    ✓ Peer-reviewed Vascular contributions Science

    Key finding: Thus, with age, the amyloid proteins associated with progressive cortical degeneration in Alzheimer's disease are also deposited in the brains of other mammals.

  2. 1987-02-20

    Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease

    ✓ Peer-reviewed Risk genes beyond APOE Science

    Four clones were isolated from an adult human brain complementary DNA library with an oligonucleotide probe corresponding to the first 20 amino acids of the beta peptide of brain amyloid from Alzheimer's disease.

  3. 1987-02-01

    Psychotropic drug use and the risk of hip fracture

    ✓ Peer-reviewed Clinical safety The New England journal of medicine

    Key finding: To assess the risk of hip fracture associated with the use of four classes of psychotropic drugs, we performed a case-control study of 1021 patients with hip fractures and 5606 controls among elderly Medicaid enrollees. +4 more findings

  4. 1987-02-01

    The genetic defect causing familial Alzheimer's disease maps on chromosome 21

    ✓ Peer-reviewed Risk genes beyond APOE Science (New York, N.Y.)

    Key finding: Alzheimer's disease is a leading cause of morbidity and mortality among the elderly. +4 more findings

  5. 1987-02-01

    The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

    ✓ Peer-reviewed Disease mechanisms Nature

    Key finding: We have now isolated and sequenced an apparently full-length complementary DNA clone coding for the A4 polypeptide. +2 more findings

  6. 1987-02-01

    The role of astrocytes in hepatic encephalopathy

    ✓ Peer-reviewed Inflammation and the immune system Neurochemical pathology

    Key finding: Whether this change is a primary event in the pathogenesis of HE or whether it is secondary to injury of some other component(s) of the CNS has not been clarified. +3 more findings

  7. 1987-02-01

    Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus

    ✓ Peer-reviewed Down syndrome and Alzheimer's Science (New York, N.Y.)

    Key finding: A complementary DNA for the beta protein suggests that it derives from a larger protein expressed in a variety of tissues.

January 1987 8

  1. 1987-01-01

    Stress, appraisal, coping, and social support as predictors of adaptational outcome among dementia caregivers

    ✓ Peer-reviewed Risk factors Psychology and Aging

    Key finding: Appraisal, coping responses, and social support and activity were significant predictors of caregiver outcome, even when severity of caregiving stressors was statistically controlled. +1 more finding

  2. 1987-01-01

    Cognitive and neurologic findings in subjects with diffuse white matter lucencies on computed tomographic scan (leuko-araiosis)

    ✓ Peer-reviewed Digital health tools Archives of neurology

    Key finding: The nine controls with leuko-araiosis had lower scores on the ESD than the 96 controls without leuko-araiosis (mean ESD with leuko-araiosis, 227.1 +/- 14; without leuko-araiosis, 237.1 +/- 8), and the difference remains significant even after adjusting for the possible confounding effects of age, sex, education, and infarct detected on computed tomography. +2 more findings

  3. 1987-01-01

    Alzheimer's neurofibrillary tangles contain unique epitopes and epitopes in common with the heat-stable microtubule associated proteins tau and MAP2

    ✓ Peer-reviewed Drug development The American journal of pathology

    Key finding: That the proteins are indeed tau and MAP2 is demonstrated by reaction of electroblotted proteins with antibodies raised in mouse and guinea pig against bovine brain tau and MAP2. +2 more findings

  4. 1987-01-01

    Vascular risk factors and leuko-araiosis

    ✓ Peer-reviewed Vascular contributions Archives of neurology

    Key finding: Leuko-araiosis was found in 49 of 140 demented patients compared with 12 out of 110 control subjects. +2 more findings

  5. 1987 no date recorded — placed by publication year

    A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Chronic Diseases

    Key finding: A weighted index that takes into account the number and the seriousness of comorbid disease was developed in a cohort of 559 medical patients. +3 more findings

  6. 1987-01-01

    The Clinical Diagnosis of Alzheimer's Disease

    ✓ Peer-reviewed Getting a diagnosis Archives of Neurology

    Key finding: Clinical and pathologic diagnoses are compared in 65 patients who had dementia and who had been studied longitudinally during life. +3 more findings

  7. 1987-01-01

    Young onset Parkinson's disease

    ✓ Peer-reviewed Risk factors Movement disorders : official journal of the Movement Disorder Society

    Key finding: In neither group have we found any association with prematurely grey hair, hypertension, diabetes, pernicious anaemia, or thyroid disorder.

  8. 1987-01-01

    Neurofibrillary tangles in Alzheimer's disease and progressive supranuclear palsy: antigenic similarities and differences. Microtubule-associated protein tau antigenicity is prominent in all types of tangles

    ✓ Peer-reviewed Disparities Acta neuropathologica

    Key finding: Whereas pretreatment of sections with phosphatase was required for the detection of tangles with Tau-1 monoclonal antibody, digestion of sections with either phosphatase or pronase had no significant effect on the staining pattern obtained with the other antibodies.

December 1986 1

  1. 1986-12-01

    CAMDEX. A standardised instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia

    ✓ Peer-reviewed Getting a diagnosis The British journal of psychiatry : the journal of mental science

    Key finding: A new interview schedule for the diagnosis and measurement of dementia in the elderly is described. +2 more findings

Browse the library by subject, with the full score breakdown →