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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,201–17,225 of 27,380 studies, newest first · page 689 of 1096.

February 2015 25

  1. 2015-02-15

    Prion Infection of Mouse Brain Reveals Multiple New Upregulated Genes Involved in Neuroinflammation or Signal Transduction

    ✓ Peer-reviewed Inflammation and the immune system Journal of Virology

    Key finding: Comparison of inflammatory markers between mice infected with scrapie strains 22L and RML indicated that the inflammatory responses and gene expression profiles in the brains were strikingly similar, even though these scrapie strains infect different brain regions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2015-02-15

    Cholesterol metabolism and homeostasis in the brain

    ✓ Peer-reviewed Vascular contributions Protein & cell

    Key finding: Cholesterol metabolism in brain is independent from that in peripheral tissues due to blood-brain barrier. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2015-02-15

    Rapidly progressive Alzheimer's disease features distinct structures of amyloid-β

    ✓ Peer-reviewed Genetics Brain : a journal of neurology

    Key finding: Rapidly progressive Alzheimer's disease that is associated with a low frequency of APOE e4 allele demonstrates considerably expanded conformational heterogeneity of amyloid-β42, with higher levels of distinctly structured amyloid-β42 particles composed of 30-100 monomers, and fewer particles composed of < 30 monomers. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2015-02-13

    Pain management at the end of life: A comparative study of cancer, dementia, and chronic obstructive pulmonary disease patients

    ✓ Peer-reviewed End-of-life care Palliative medicine

    Key finding: Despite the fact that pain is the most common complaint at the end of life, pain management may be suboptimal for some primary diagnoses. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2015-02-13

    An evaluation of palliative care contents in national dementia strategies in reference to the European Association for Palliative Care white paper

    ✓ Peer-reviewed End-of-life care International psychogeriatrics

    Key finding: National dementia strategies cover part of the recent definition of palliative care in dementia, although they do not frequently label these references as "palliative care." +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2015-02-13

    Parkinson risk in idiopathic REM sleep behavior disorder: preparing for neuroprotective trials

    ✓ Peer-reviewed How common it is Neurology

    Key finding: Using stratification with simply assessed markers, it is now not only possible, but practical to include patients with RBD in neuroprotective trials against Parkinson disease, multiple system atrophy, and dementia with Lewy bodies. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2015-02-13

    Effectiveness of an Internet intervention for family caregivers of people with dementia: results of a randomized controlled trial

    ✓ Peer-reviewed Caregiving PloS one

    Key finding: The Internet course 'Mastery over Dementia' offers an effective treatment for family caregivers of people with dementia reducing symptoms of depression and anxiety. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2015-02-12

    Models of home care services for persons with dementia: a narrative review

    ✓ Peer-reviewed Health systems and care delivery International psychogeriatrics

    Key finding: Case management for persons with dementia may increase use of community-based services and delay nursing home admission. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2015-02-12

    Beta-amyloid imaging with florbetaben

    ✓ Peer-reviewed Treatments Clinical and translational imaging

    Key finding: Further, the favorable results of human pharmacokinetics, safety, and dosimetry evaluation of florbetaben are presented. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2015-02-11

    The JAK/STAT3 Pathway Is a Common Inducer of Astrocyte Reactivity in Alzheimer's and Huntington's Diseases

    ✓ Peer-reviewed Inflammation and the immune system The Journal of Neuroscience

    Key finding: The Janus kinase/signal transducer and activator of transcription 3 (JAK/STAT3) pathway is associated with reactive astrocytes in models of acute injury, but it is unknown whether this pathway is directly responsible for astrocyte reactivity in progressive pathological conditions such as ND. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2015-02-11

    Consensus views on advance care planning for dementia: a Delphi study

    ✓ Peer-reviewed End-of-life care Health & social care in the community

    Key finding: It is suggested that ACP should include general discussion of values as well as coverage of specific points.

    Full summary, score breakdown and related studies → Original source

  12. 2015-02-11

    MIND diet associated with reduced incidence of Alzheimer's disease

    ✓ Peer-reviewed Prevention and risk Alzheimer s & Dementia

    High adherence to all three diets may reduce AD risk.

    Full summary, score breakdown and related studies → Original source

  13. 2015-02-11

    Mild cognitive impairment in Parkinson's disease and its progression onto dementia: a 16-year outcome evaluation of the Denbighshire cohort

    ✓ Peer-reviewed Mild cognitive impairment International journal of geriatric psychiatry

    Key finding: Mild cognitive impairment in Parkinson's disease is an important predictor for the progression to PDD.

    Full summary, score breakdown and related studies → Original source

  14. 2015-02-11

    Amyloid-β deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progression

    ✓ Peer-reviewed Mild cognitive impairment Brain : a journal of neurology

    Key finding: Cross-sectional functional magnetic resonance imaging studies using a memory task in patients with mild cognitive impairment have produced discordant results, with some studies reporting increased hippocampal activity--consistent with findings in genetic at-risk populations--and other studies reporting decreased hippocampal activity, relative to normal controls. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2015-02-10

    Amyloid-related imaging abnormalities-haemosiderin (ARIA-H) in patients with Alzheimer's disease treated with bapineuzumab: a historical, prospective secondary analysis

    ✓ Peer-reviewed Treatments Journal of neurology, neurosurgery, and psychiatry

    Key finding: ARIA-H represents a spectrum of MRI findings due to haemosiderin deposition that appears to be related to impaired vascular integrity. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2015-02-09

    Multimodal analysis of functional and structural disconnection in Alzheimer's disease using multiple kernel SVM

    ✓ Peer-reviewed Digital health tools Human brain mapping

    Key finding: We ran the support vector machine (SVM) algorithm and validated the results using leave-one-out cross-validation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2015-02-09

    Effectiveness of exercise programs to reduce falls in older people with dementia living in the community: a systematic review and meta-analysis

    ✓ Peer-reviewed Clinical safety Clinical interventions in aging

    Key finding: However, further research is needed with studies using larger sample sizes, standardized measurement outcomes, and longer follow-up periods, to inform evidence-based recommendations. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2015-02-07

    Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease

    ✓ Peer-reviewed Treatments Journal of controlled release : official journal of the Controlled Release Society

    Key finding: Both GSH-PEG DMPC and GSH-PEG EYPC liposomes significantly increased the standard uptake values (SUV) of VHH-pa2H in the blood of the animals compared to free VHH-pa2H. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2015-02-07

    The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice

    ✓ Peer-reviewed Disease mechanisms Neuropharmacology

    Key finding: These results were supported by a significant reduction in the paired helical filament (PHF), β-amyloid (βA) 1-40 and βA 1-42 levels and a decrease in BACE1-mediated cleavage of APP (into CTFβ). +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2015-02-07

    Myoclonic epilepsy in Down syndrome and Alzheimer disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Neurologia (Barcelona, Spain)

    Key finding: The association of generalized epilepsy with elderly DS represents an epiphenomenon in evolution which is associated with a progressive deterioration of cognitive and motor functions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2015-02-07

    Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI

    ✓ Peer-reviewed Genetics Circulation. Cardiovascular genetics

    Key finding: We identified 4 novel genetic loci that implicate inflammatory and glial proliferative pathways in the development of WMH in addition to previously proposed ischemic mechanisms. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2015-02-06

    Long-Acting Intranasal Insulin Detemir Improves Cognition for Adults with Mild Cognitive Impairment or Early-Stage Alzheimer's Disease Dementia

    ✓ Peer-reviewed Genetics Journal of Alzheimer s Disease

    Key finding: These trials used regular insulin, which has a shorter half-life compared to long-lasting insulin analogues such as insulin detemir. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2015-02-05

    Diagnosis and treatment of depression and cognitive impairment in late life

    ✓ Peer-reviewed Risk factors Annals of the New York Academy of Sciences

    Key finding: For example, executive dysfunction often accompanies late-life depression, influences performance across cognitive domains, and is associated with poor antidepressant treatment outcomes.

    Full summary, score breakdown and related studies → Original source

  24. 2015-02-04

    Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis

    ✓ Peer-reviewed Lewy body dementia The Lancet. Neurology

    Key finding: For neuropsychology measures, we noted the earliest significant differences between mutation carriers and non-carriers 5 years before expected onset, when differences were significant for all measures except for tests of immediate recall and verbal fluency. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2015-02-03

    The Effect of Preinjury Sleep Difficulties on Neurocognitive Impairment and Symptoms After Sport-Related Concussion

    ✓ Peer-reviewed Risk factors The American Journal of Sports Medicine

    Key finding: The findings may help clinicians identify athletes who are at risk for worse impairments after a concussion due to preinjury sleep difficulties. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →