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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 15,951–15,975 of 27,380 studies, newest first · page 639 of 1096.

July 2016 22

  1. 2016-07-05

    Proteolytic processing of Neuregulin-1

    ✓ Peer-reviewed Treatments Brain research bulletin

    Key finding: The type 1 oriented stub is further cleaved by γ-secretase in the transmembrane domain with a putative role in intracellular domain (ICD) signaling, while the type II oriented stub is cleaved by signal peptidase like proteases (SPPLs). +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-07-04

    Psychosocial interventions for people with dementia: An overview and commentary on recent developments

    ✓ Peer-reviewed Prevention trials Dementia (London, England)

    Key finding: An influential review in 2010 concluded that non-pharmacological multi-component interventions have positive effects on cognitive functioning, activities of daily living, behaviour and mood of people with dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2016-07-04

    Anxiety as a Predictor for Cognitive Decline and Dementia: A Systematic Review and Meta-Analysis

    ✓ Peer-reviewed Risk factors The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Twenty studies met inclusion criteria. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2016-07-02

    Hearing and dementia

    ✓ Peer-reviewed Risk factors Journal of neurology

    Key finding: Hearing deficits associated with cognitive impairment have attracted much recent interest, motivated by emerging evidence that impaired hearing is a risk factor for cognitive decline. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2016-07-01

    P2‐003: Clinical Trial Design of Cread: A Randomized, Double‐Blind, Placebo‐Controlled, Parallel‐Group Phase 3 Study to Evaluate Crenezumab Treatment in Patients with Prodromal‐To‐Mild Alzheimer’s Disease

    ✓ Peer-reviewed Treatments Alzheimer s & Dementia

    Key finding: Although the co-primary endpoints (ADAS-Cog12 and CDR-SB) were not met, pre-planned exploratory analyses suggest that treatment with crenezumab compared with placebo leads to increasing benefit on both endpoints in progressively milder subsets of AD patients at the higher dose (15 mg/kg IV q4w). +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2016-07-01

    P1‐146: Chlamydia Pneumoniae‐Infected Astrocytes Alter Their Expression of Adam10, Bace1, and Presenilin‐1 Proteases

    ✓ Peer-reviewed Risk genes beyond APOE Alzheimer s & Dementia

    Key finding: These data indicate that infection of human astrocytes with Chlamydia pneumoniae strain AR39 promotes the processing of βAPP characteristic of Alzheimer’s Disease through enhancing BACE1 and PSEN1, but not ADAM10, protein levels.

    Full summary, score breakdown and related studies → Original source

  7. 2016-07 month only

    [Exercise and Physical Activity for Dementia Prevention]

    ✓ Peer-reviewed Prevention trials Brain and nerve = Shinkei kenkyu no shinpo

    Key finding: The effects of exercise and physical activity on cognitive function and brain health have been established by longitudinal and intervention studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2016-07-01

    Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid

    ✓ Peer-reviewed Disease mechanisms Pharmacognosy reviews

    Key finding: The previous studies showed that the ingestion of flavonoids reduces the risk of cardiovascular diseases, metabolic disorders, and certain types of cancer. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2016-07-01

    Imaging synaptic density in the living human brain

    ✓ Peer-reviewed Disease mechanisms Science translational medicine

    Key finding: Changes in the number of synapses are associated with numerous brain disorders, including Alzheimer's disease and epilepsy. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2016-07-01

    In Vivo Tau, Amyloid, and Gray Matter Profiles in the Aging Brain

    ✓ Peer-reviewed Brain scans and imaging The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: We found that Tau and amyloid-β deposits are associated with distinctive spatial patterns of brain tissue loss. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2016-07-01

    Neurofilament light chain: a biomarker for genetic frontotemporal dementia

    ✓ Peer-reviewed Biomarkers Annals of clinical and translational neurology

    Key finding: NfL in both serum and CSF has the potential to serve as a biomarker for clinical disease onset and has a prognostic value in genetic FTD.

    Full summary, score breakdown and related studies → Original source

  12. 2016-07-01

    Sphingosine-1-Phosphate (S1P) and S1P Signaling Pathway: Therapeutic Targets in Autoimmunity and Inflammation

    ✓ Peer-reviewed Inflammation and the immune system Drugs

    Key finding: S1P-S1PR signaling has been well characterized in immune trafficking and activation in innate and adaptive immune systems. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2016-07-01

    Genetic variations underlying Alzheimer's disease: evidence from genome-wide association studies and beyond

    ✓ Peer-reviewed TREM2 and immune genetics The Lancet. Neurology

    Key finding: These loci are estimated to explain about 28% of the heritability of liability, 30% of familial risk, and over 50% of sibling recurrence risk of developing Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2016-07-01

    TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia

    ✓ Peer-reviewed TREM2 and immune genetics Neuron

    Key finding: Starting from an unbiased protein microarray screen, we identified a set of lipoprotein particles (including LDL) and apolipoproteins (including CLU/APOJ and APOE) as ligands of TREM2. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2016-07-01

    Genomics of Alzheimer Disease: A Review

    ✓ Peer-reviewed Risk genes beyond APOE JAMA neurology

    Key finding: Observations Genotype-phenotype correlations of AD are presented to provide a comprehensive appreciation of the spectrum of disease causation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2016-07-01

    Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-β levels in brain

    ✓ Peer-reviewed Mild cognitive impairment Journal of neurochemistry

    Key finding: Here, we report that ROCK1 protein levels were elevated in mild cognitive impairment due to AD (MCI) and AD brains compared to controls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2016-07-01

    Subjective cognitive decline: The first clinical manifestation of Alzheimer's disease?

    ✓ Peer-reviewed Mild cognitive impairment Dementia & neuropsychologia

    Key finding: These findings support the idea that subjective cognitive complaints may be an early clinical marker that precedes mild cognitive impairment due to Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2016-07-01

    Cognitive Profiles on the Severe Impairment Battery Are Similar in Alzheimer Disease and Down Syndrome With Dementia

    ✓ Peer-reviewed Down syndrome and Alzheimer's Alzheimer disease and associated disorders

    Key finding: Previous research has revealed similarities in the neuropathology, clinical presentation, and risk factors between persons with Alzheimer disease from the general population (GP-AD) and those with Down syndrome (DS-AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2016-07-01

    Homocysteine, B Vitamins, and Cognitive Impairment

    ✓ Peer-reviewed Risk factors Annual review of nutrition

    Key finding: Prospectively, elevated tHcy is associated with cognitive decline, white matter damage, brain atrophy, neurofibrillary tangles, and dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2016-07-01

    Comparison of Feature Selection Techniques in Machine Learning for Anatomical Brain MRI in Dementia

    ✓ Peer-reviewed Digital health tools Neuroinformatics

    Key finding: NC classification, the variability in the test accuracy due to the subject sample did not vary between different methods and exceeded the variability due to different classifiers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2016-07-01

    The ARIC-PET amyloid imaging study: Brain amyloid differences by age, race, sex, and APOE

    ✓ Peer-reviewed Disparities Neurology

    Key finding: In this community-based cohort without dementia, florbetapir uptake is associated with older age and APOE genotype. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2016-07-01

    A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: A number of current issues suggest that an unbiased descriptive classification scheme for these biomarkers would be useful.

    Full summary, score breakdown and related studies → Original source

June 2016 3

  1. 2016-06-29

    Palliative and end-of-life care for people living with dementia in care homes: part 2

    ✓ Peer-reviewed End-of-life care Nursing standard (Royal College of Nursing (Great Britain) : 1987)

    Key finding: This article, the second of two, provides healthcare practitioners with an overview of best practice in palliative and end-of-life care, including nutrition, hydration, oral hygiene and pain management. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-06-29

    18F-AV-1451 tau PET imaging correlates strongly with tau neuropathology in MAPT mutation carriers

    ✓ Peer-reviewed Brain scans and imaging Brain : a journal of neurology

    Key finding: This mutation results in 3- and 4-repeat tau aggregates similar to those in Alzheimer's disease, and many of the mutation carriers initially suffer from memory impairment and temporal lobe atrophy.

    Full summary, score breakdown and related studies → Original source

  3. 2016-06-29

    Tau PET in Alzheimer disease and mild cognitive impairment

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Tau PET imaging with (18)F-AV-1451 could serve as an in vivo biomarker for the evaluation of AD-related tau pathology and monitoring disease progression. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →