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59/100

✓ Peer-reviewed alzhub usefulness score 59 out of 100. Mild cognitive impairment

Topic: Risk, prevention and care in population studies

Plain-language summary

Background It has been reported that up to 42% of the population aged over 60 are affected by mild cognitive impairment (MCI) worldwide. This study aims to investigate the prevalence and progression of MCI through a meta-analysis. Methods We searched Embase and PubMed for relevant literature. Stable disease rate (SR), reversion rate (RR), dementia rate (DR), and Alzheimer's disease rate (AR) were used to evaluate the progression of MCI. The prevalence and progression rates were both obtained by reported percentile and indirect data analysis. Additionally, we carried out sensitivity analysis of each index by excluding some studies due to influence analysis with the most publication bias. Results Effect size (ES) was used to present adjusted overall prevalence (16%) and progression rates including SR (45%), RR (15%), DR (34%), and AR (28%) of MCI. Compared with clinic-based outcomes, MCI prevalence, SR, and RR are significantly higher in community, while DR and AR are lower. Despite significant heterogeneity found among the studies, no publication bias was observed. Conclusions Age and gender were observed to be associated with MCI, in which age was considered as an impact factor for DR. The strong heterogeneity may result from variations in study design and baselines. Standardized MCI criteria were suggested to systematically evaluate MCI in the future.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Hu, C., Yu, D., Sun, X., Zhang, M., Wang, L., & Qin, H. (2017). The prevalence and progression of mild cognitive impairment among clinic and community populations: a systematic review and meta-analysis. International psychogeriatrics. https://doi.org/10.1017/s1041610217000473

Vancouver

Hu C, Yu D, Sun X, Zhang M, Wang L, Qin H. The prevalence and progression of mild cognitive impairment among clinic and community populations: a systematic review and meta-analysis. International psychogeriatrics. 2017. doi:10.1017/s1041610217000473. PMID: 28884657.

BibTeX

@article{hu2017-28884657,
  author  = {Hu, C. and Yu, D. and Sun, X. and Zhang, M. and Wang, L. and Qin, H.},
  title   = {{The prevalence and progression of mild cognitive impairment among clinic and community populations: a systematic review and meta-analysis}},
  journal = {International psychogeriatrics},
  year    = {2017},
  doi     = {10.1017/s1041610217000473},
  pmid    = {28884657},
  url     = {https://doi.org/10.1017/s1041610217000473}
}

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How to read this study

Design: this is a pooled review. It combines earlier studies, so it is only as good as the studies it pools. Check how many were included, whether they were similar enough to combine, and whether the authors report inconsistency between them.
Size: the record gives no participant count. Look for one in the original before trusting a pattern.
Effect: the record gives no effect size, so the summary above cannot say how large any difference was.

What the evidence grade means here

This page is graded high. alzhub.org assigns the grade automatically from keywords in the abstract, not from reading the paper. High means the abstract mentions a randomized design, a meta-analysis or a systematic review. It can add at most 5 of the 100 points in the study score, and it is a label about design, not a verdict on whether the findings are true.

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Key findings

Results Effect size (ES) was used to present adjusted overall prevalence (16%) and progression rates including SR (45%), RR (15%), DR (34%), and AR (28%) of MCI.
Compared with clinic-based outcomes, MCI prevalence, SR, and RR are significantly higher in community, while DR and AR are lower.
Despite significant heterogeneity found among the studies, no publication bias was observed.
Conclusions Age and gender were observed to be associated with MCI, in which age was considered as an impact factor for DR.
The strong heterogeneity may result from variations in study design and baselines.

Why it matters

This meta-analysis of PubMed and Embase studies estimated an adjusted MCI prevalence of 16%. Among people with MCI, 45% stayed stable, 15% returned to normal, 34% progressed to dementia and 28% to Alzheimer's disease. Progression to dementia and Alzheimer's was lower in community samples than in clinic samples, while stability and reversion were higher. The authors say the studies varied a lot and call for standardized MCI criteria, so these are pooled averages, not personal risks, and the study tests no treatment.

Study details

Study designmeta-analysis
Evidence strengthHigh

How this study scored 59/100

Published in a peer-reviewed journal, and it is a meta-analysis pooling many studies. Scored zero for sample size, effect reported and studied in people because the record does not state it. We have no data on institution's track record, so that was left out: it earned 57 of the 97 points we could judge it on, which is 59 out of 100.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (International psychogeriatrics)
Journal's citation record	2 / 4	International Psychogeriatrics: journal h-index 161 (OpenAlex, 2026-10-29)
Study design	12 / 12	A meta-analysis pooling many studies
Strength of evidence	5 / 5	Rated “high” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	2 / 5	2017 — within 10 year(s) of the newest study here
Sample size	0 / 4	Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	0 / 3	Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomized / blinded	0 / 2	A review of other studies — randomization is not credited here
Times cited	5 / 7	Cited 197 times (OpenAlex, 2026-10-10)
Citations per year	3 / 5	17.9 citations a year over 11 year(s) since 2017
Impact for its field and year	3 / 6	Cited 3.0× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	2 / 6	Cited by 7 other studies in this library
Still being cited	3 / 4	Cited 55 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	1 / 4	Last-listed author Hongyun Qin: h-index 11 (OpenAlex, whole career)
Institution's track record	— / 3	No institution listed in OpenAlex — left out of this score
Multicenter collaboration	0 / 3	OpenAlex lists 0 institution(s) in 0 countries — scores zero (affiliation lists can be incomplete)
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 28884657)
Free to read	0 / 2	Behind a paywall — scores zero
Points	57 / 97	Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 57 of the 97 points we could judge it on is 59 out of 100.
Total	59 / 100	—

What each of these 20 components measures, and what this score is not →

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